Test Price
2,800 AED✅ Home Collection Available
ASL Gene (Argininosuccinic Aciduria) Genetic Test in UAE | 2800 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity: Precision genetic analysis via ISO 9001:2015 certified next-generation sequencing (NGS) for the ASL gene.
- Premium Home Collection (8 AM – 11 PM): Certified VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available across Dubai, Abu Dhabi, and all Emirates.
- Telephonic Post-Test Clinical Guidance: Detailed result interpretation provided by a DHA-registered Consultant Medical Geneticist.
- Direct Insurance Billing Verification: Submit your policy details via WhatsApp at +971 54 548 8731 for rapid coverage confirmation.
Test Overview & Methodology
The ASL Gene (Argininosuccinic Aciduria) Genetic Test employs advanced next-generation sequencing (NGS) to detect pathogenic variants in the ASL gene. This analysis is the definitive molecular diagnostic method for Argininosuccinic Aciduria, a severe urea cycle disorder that can lead to life-threatening hyperammonemia if untreated. Our DHA-licensed laboratory (License No. 1143) ensures uncompromising accuracy and regulatory compliance throughout the testing process, from sample reception to final clinical report generation.
| Feature | Our ASL NGS Test | Traditional Sanger Sequencing |
|---|---|---|
| Precision | Full gene coverage (all exons, intron-exon boundaries) with ≥99.9% analytical sensitivity | Targeted hot-spot analysis only; lower variant detection (≈95%) |
| Method | Next-Generation Sequencing (NGS) – high-throughput, clinically validated | Conventional capillary sequencing, limited throughput |
| Turnaround Time | 3–4 weeks | 4–6 weeks |
| Cost | 2800 AED | ≈2500–3000 AED |
| Regulatory Compliance | DHA Licensed, PDPL 2021, Federal Law No. 2 of 2019 | Variable; often lacks explicit DHA alignment |
Physician Insight & Safety Protocols
“Understanding your genetic health empowers families to make informed metabolic and dietary interventions. The NGS-based analysis of the ASL gene is the most reliable laboratory tool for confirming a diagnosis of argininosuccinic aciduria. Our team ensures that each step, from pre-test counseling to the final clinical report, is conducted under the highest regulatory standards of the UAE.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠️ Important Clinical Advisory
Do not discontinue any prescribed medication or dietary management plan without consulting your treating physician. This genetic test is not a substitute for immediate emergency care.
Exclusion Criteria & Safety Notes
- Not intended for emergency diagnosis of acute hyperammonemia.
- Pre-test genetic counseling is mandatory; a detailed pedigree chart of family medical history must be reviewed.
- Testing of minors requires informed parental/guardian consent, strictly following Federal Decree-Law No. 4 of 2016 on Medical Liability.
- All personal health data is protected under the UAE PDPL (Federal Decree-Law No. 45 of 2021).
Emergency Red Flags
If you or the individual being tested experiences unexplained vomiting, lethargy, seizures, disorientation, or an ammonia-like breath odour, seek immediate emergency medical attention – these could signal a metabolic crisis unrelated to the test result.
Patient FAQ & Clinical Guidance
1. What is the ASL gene NGS test and who should consider it?
The ASL NGS test analyzes the entire ASL gene for mutations causing argininosuccinic aciduria, a rare metabolic disorder. It is recommended for individuals with clinical symptoms (e.g., hyperammonemia, vomiting), family history of the disease, or as a carrier screening tool. In the UAE, it is also used for pre-conception risk assessment under DHA guidelines.
2. How is the sample collected and what is the turnaround time?
A small blood sample – whole blood, extracted DNA, or a single drop on an FTA card – is collected by a certified phlebotomist at your home. Our 8 AM–11 PM mobile team uses hospital-grade cold-chain transport; results are ready in 3–4 weeks, with an optional expedited service upon request.
3. Is this test covered by health insurance in the UAE?
We offer direct billing verification with all major UAE insurers upon receipt of your policy details via WhatsApp. Send your insurance card to +971 54 548 8731 and our team will confirm coverage within 2 hours. Pre-authorization support is also provided.
4. What genetic changes does this test detect?
This test detects single nucleotide variants (SNVs), small insertions and deletions (indels), and splice-site mutations across the ASL gene. All identified variants are interpreted according to ACMG/AMP guidelines and correlated with clinical phenotype for accurate diagnostic reporting.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Healthcare Compliance: All genetic and personal data are processed in strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Our DHA-licensed facility (License No. 1143) ensures complete regulatory compliance for every diagnostic service delivered.
Clinical & Logistical Metadata
| Test Name | ASL Gene (Argininosuccinic Aciduria) Genetic Test (NGS) |
| Price (AED) | 2800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Dried Blood Spot. VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM. |
| Methodology Used | Next-Generation Sequencing (NGS) – Full gene coverage with ≥99.9% analytical sensitivity |
| ICD-10-CM Code | E72.53 – Argininosuccinic aciduria |
| LOINC Code | 90237-0 – ASL gene targeted mutation analysis |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | DNA Labs UAE – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians