Test Price
2,800 AEDโ Home Collection Available
ARG1 Gene Arginase Deficiency Genetic Test in the UAE | AED 2,800 | DHA Licensed
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% Analytical Sensitivity via ISO 9001:2015 Certified NGS Workflow.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM โ 11 PM).
- Clinical Guidance: Complimentary Post-Test Teleconsultation with a DHA-Licensed Consultant Medical Geneticist.
- Insurance & Billing: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The ARG1 gene NGS test detects pathogenic variants causing arginase deficiency, a urea cycle disorder leading to hyperargininemia, neurological deterioration, and spasticity, enabling precise diagnosis and family planning. This comprehensive analysis uses Illumina-based next-generation sequencing to cover all coding exons, splice sites, and deep intronic regions with >99.9% sensitivity.
| Feature | Our NGS Panel (Precision) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | >99.9% sensitivity, full gene coverage including deep intronic variants | Limited to targeted known mutations; may miss novel variants |
| Method | Next-Generation Sequencing (Illumina platform), LC-MS/MS validated | Capillary electrophoresis; gene-wide coverage incomplete |
| Speed | 3โ4 weeks from sample receipt | 2โ3 weeks (but with lower diagnostic yield) |
Physician Insight & Safety Protocols
โUnderstanding the genetic basis of a childโs neurological symptoms can be deeply distressing for families. This test is a critical step, but it must always be correlated with biochemical findings, clinical history, and a comprehensive pedigree chart obtained during genetic counselling. A negative result does not exclude the diagnosis if clinical suspicion remains high.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication & Dietary Advisory
Never stop prescribed metabolic therapies, protein-restricted diets, or ammonia-scavenging medications without explicit guidance from your treating metabolic specialist. Sudden discontinuation may trigger acute hyperammonemia requiring emergency intervention. Always consult your physician before making any changes.
Safety Exclusion & Emergency Red Flags
- Exclusion Criteria: Age under 6 months without clear clinical indication; inability to provide informed consent; recent blood transfusion within 2 weeks that may confound DNA analysis.
- Emergency Red Flags: If the patient develops acute hyperammonemia symptoms such as lethargy, vomiting, seizures, or respiratory alkalosis, seek immediate medical attention at the nearest emergency department. This test is not a substitute for urgent metabolic crisis management.
Patient FAQ & Clinical Guidance
1. What is the purpose of the ARG1 gene test?
It identifies DNA mutations in the ARG1 gene to confirm arginase deficiency diagnosis, carrier status, or guide treatment. This NGS test detects both previously reported and novel pathogenic variants, providing a comprehensive genetic assessment for metabolic specialists.
2. How is the sample collected in the UAE?
A DHA-licensed phlebotomist collects blood via home visit; DNA can also be extracted from an FTA card. The service operates daily 8 AMโ11 PM with an ISO-certified cold-chain protocol, ensuring sample stability for NGS.
3. What is the turnaround time and cost?
Results are delivered within 3 to 4 weeks at a price of AED 2,800 inclusive of genetic counselling. The fee covers the complete workflow: sample collection, NGS sequencing, bioinformatics analysis, and a post-test teleconsultation session.
UAE Regulatory & Data Privacy Adherence
This service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is processed under ISO 9001:2015 certified workflows (Cert: INT/EGQ/2509DA/3139) and stored in encrypted archives within the UAE. For any data subject requests or privacy concerns, contact our Data Protection Officer via WhatsApp at +971 54 548 8731.
Clinical & Logistical Metadata
| Test Name | ARG1 Gene Arginase Deficiency Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 weeks from sample receipt |
| Sample Type / Matrix | Peripheral whole blood (EDTA or FTA card) |
| Methodology Used | Next-Generation Sequencing (Illumina), LC-MS/MS validation |
| ICD-10-CM Code | E72.21 |
| LOINC Code | 76527-5 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians