Test Price
4,600 AED✅ Home Collection Available
Chronic Myeloid Leukemia (CML) NGS Panel in UAE | 4600 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Chronic Myeloid Leukemia NGS Panel is a comprehensive next‑generation sequencing test that screens for BCR‑ABL1 kinase domain mutations and additional gene alterations driving CML progression, informing precise tyrosine kinase inhibitor selection. In the UAE, this ISO‑certified molecular profiling enables hematologists and oncologists to tailor therapy with DHA‑mandated accuracy.
| Feature | Our CML NGS Panel | Standard BCR‑ABL qPCR Test |
|---|---|---|
| Precision | Detects 30+ gene mutations including ABL1, ASXL1, RUNX1; identifies emerging resistance variants | Quantifies only BCR‑ABL1 transcript levels; misses non‑ABL1 resistance mechanisms |
| Methodology | NGS (Illumina® platform) with bioinformatics validated per DHA/MOHAP standards | Real‑time quantitative PCR (RQ‑PCR) |
| Speed | Samples accepted on scheduled cycles; report delivered within 15 business days (maximum) | Typically 3–5 working days |
Physician Insight & Safety Protocols
“As a consultant in medical genetics, I stress that CML NGS results must be integrated with complete blood counts, bone marrow morphology, and medication history. This panel reveals resistance mutations that guide targeted therapy, but treatment adjustments require a multidisciplinary approach. Never modify tyrosine kinase inhibitor doses without formal hematology review – abrupt changes may trigger disease acceleration.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)⚠️ Medication Advisory
Do not discontinue prescribed tyrosine kinase inhibitors or any chemotherapy agent without consulting your hematologist. Abrupt cessation can lead to accelerated phase transformation or blast crisis. Always discuss any planned changes with your treating physician.
Exclusion Criteria & Emergency Signs
- Exclusion Criteria: Platelet count < 50,000/µL, INR > 1.5, active infection at collection site, uncontrolled bleeding diathesis, pregnancy (for bone marrow aspirate), and inability to provide mandatory NGS Test Requisition Form.
- ER Red Flags: Fever > 38.5°C, sudden severe bone pain, mental status changes, uncontrolled bleeding from puncture site, or signs of anaphylaxis — seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What exactly does the CML NGS panel detect and why is it important?
The CML NGS panel identifies BCR‑ABL1 kinase domain mutations and other genetic alterations that drive resistance to tyrosine kinase inhibitors, enabling personalized therapy adjustments.
2. How is the sample collected and what preparation is required?
A trained phlebotomist draws 3 mL whole blood or performs a bone marrow aspirate in an EDTA tube under hospital supervision; you must fast for 8 hours and complete the NGS Requisition Form beforehand. Collection occurs only at an accredited hospital facility.
3. Will my health insurance in the UAE cover this test?
Most UAE insurers reimburse the CML NGS panel when supported by a hematologist’s referral; we verify your coverage directly via WhatsApp at +971 54 548 8731 before scheduling.
UAE Regulatory & Data Privacy Adherence
This service strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Our facility operates under DHA License 1143, ISO 9001:2015 certification (INT/EGQ/2509DA/3139), and employs only DHA‑licensed healthcare professionals.
Clinical & Logistical Metadata
| Test Name | Chronic Myeloid Leukemia (CML) NGS Panel |
| Price (AED) | 4600 |
| Turnaround Time | 15 business days (maximum) |
| Sample Type / Matrix | Bone Marrow Aspirate or Peripheral Blood (Hospital Collection Only) |
| Methodology Used | Next-Generation Sequencing (Illumina® platform) |
| ICD-10-CM Code | C92.10, C92.11, C92.12 |
| LOINC Code | 92928-0 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians