Test Price
2,500 AED✅ Home Collection Available
FISH Eosinophilic Leukemia Panel (Fluorescence In-Situ Hybridization) – UAE Diagnostic Genetic Test
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Telephonic Post-Test Clinical Guidance by a DHA-Licensed Consultant Medical Geneticist.
- Direct Insurance Billing Verification via WhatsApp +971 54 548 8731.
Compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Test Overview & Methodology
The FISH Eosinophilic Leukemia Panel detects PDGFRA, PDGFRB, FGFR1, and PCM1-JAK2 rearrangements via Fluorescence In-Situ Hybridization (FISH), enabling precise classification of eosinophilic neoplasms and guiding targeted tyrosine kinase inhibitor therapy. This genetic test is critical for differentiating reactive eosinophilia from clonal eosinophilic disorders and for selecting molecularly targeted treatments.
| Feature | Our FISH Panel | Standard Karyotyping |
|---|---|---|
| Methodology | Fluorescence In-Situ Hybridization (FISH) | Conventional Chromosome Analysis |
| Diagnostic Sensitivity | 99.9% for targeted rearrangements | Approximately 60–75% (culture-dependent) |
| Turnaround Time | 4 Working Days | 5–7 Working Days |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I emphasize that the FISH Eosinophilic Leukemia Panel detects specific chromosomal rearrangements that guide targeted therapy selection. Results must be interpreted in the context of clinical symptoms, peripheral blood smear, and bone marrow morphology. This test does not replace a comprehensive diagnostic workup and should be correlated with other laboratory findings.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Clinical Advisory
Medical Attention Required
If you experience persistent fever (>38.5°C), unexplained weight loss, severe bone pain, confusion, or sudden vision changes, seek immediate medical evaluation. These may indicate disease progression or complications requiring urgent intervention.
Exclusion Criteria
Sample Requirements
- Inadequate sample volume (minimum 5 mL whole blood in sodium heparin tube or 4 mL bone marrow aspirate in two green-top tubes).
- Clotted specimen or frozen sample (cell lysis).
- Missing mandatory Chromosome & FISH Requisition Form (Form 17).
Patient FAQ & Clinical Guidance
1. What is an eosinophilic leukemia FISH panel?
The FISH eosinophilic leukemia panel is a genetic test that identifies specific chromosomal rearrangements (PDGFRA, PDGFRB, FGFR1, PCM1-JAK2) in blood or bone marrow cells to diagnose eosinophilic leukemia and guide tyrosine kinase inhibitor therapy. It is more sensitive than standard karyotyping for detecting these abnormalities.
2. How is the sample collected for this test?
A 5 mL whole blood sample in a sodium heparin tube or a 4 mL bone marrow aspirate from two green-top tubes is required. The sample must be kept at room temperature (18–22°C) and never frozen. Collection is performed exclusively in a hospital setting; home phlebotomy is not available due to the invasive nature of the procedure.
3. How long does it take to get the results?
Results are typically reported within 4 working days from the day the sample arrives at the lab before 4 PM. Turnaround time may vary if additional validation steps are required.
4. Is this test covered by insurance in the UAE?
Many UAE insurance plans cover this genetic test when ordered by a specialist. Contact our billing team via WhatsApp at +971 54 548 8731 to verify your coverage and obtain a pre‑authorization if needed.
UAE Regulatory & Data Privacy Adherence
This test is performed under the regulatory oversight of the Dubai Health Authority (DHA) Facility License Number 1143. Our practice strictly complies with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring secure handling of your health data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing electronic health records and telemedicine.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – defining patient consent and clinical safety standards.
All personnel handling your sample and results are bound by strict confidentiality agreements. Your genetic information is processed in accredited laboratories and stored securely with restricted access.
Clinical & Logistical Metadata
| Test Name | FISH Eosinophilic Leukemia Panel (PDGFRA, PDGFRB, FGFR1, PCM1-JAK2) |
| Price (AED) | 2,500 AED |
| Turnaround Time | 4 Working Days |
| Sample Type / Matrix | Peripheral whole blood (sodium heparin) or bone marrow aspirate. Hospital collection only. |
| Methodology Used | Fluorescence In-Situ Hybridization (FISH) with break-apart and fusion probes |
| ICD-10-CM Code | C94.8 (Eosinophilic leukemia) |
| LOINC Code | 60540-3 (FISH panel - Tissue) |
| DHA Facility License & Address | License No. 1143 · Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians