Test Price
2,800 AEDโ Home Collection Available
RFX5 Gene (Bare Lymphocyte Syndrome Type 2) Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
The RFX5 Next-Generation Sequencing (NGS) genetic test delivers 99.9% diagnostic sensitivity for detecting pathogenic variants associated with Bare Lymphocyte Syndrome Type 2 (MHC Class II Deficiency). Performed at DNA Labs UAE (DHA License 1143), this analysis includes comprehensive exon coverage and copy number variation detection. The service features VIP mobile phlebotomy and temperature-controlled cold-chain home collection (available daily 8 AMโ11 PM), telephonic post-test guidance, and direct billing support via WhatsApp +971545488731.
Test Overview & Methodology
The RFX5 NGS test screens for pathogenic variants in the RFX5 gene that cause Bare lymphocyte syndrome type II (MHC class II deficiency) โ a severe combined immunodeficiency. This advanced sequencing analysis provides definitive genetic confirmation, essential for accurate diagnosis, family screening, and personalised treatment strategies in the UAE healthcare system.
| Feature | Our Test (NGS โ Next Generation Sequencing) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Diagnostic Precision | >99.9% sensitivity & specificity for RFX5 coding region | ~95% sensitivity; limited to known mutation hotspots |
| Turnaround Time | 3โ4 Weeks (comprehensive bioinformatics) | 2โ3 Weeks (single gene) |
| Methodology | High-throughput NGS with full exon coverage and copy number detection | Capillary electrophoresis sequencing of PCR amplicons |
Physician Insight & Safety Protocols
โAs a consultant medical geneticist, I emphasize that a positive RFX5 variant must be correlated with clinical immunophenotyping and flow cytometry. This test provides definitive molecular confirmation but does not replace comprehensive immunological assessment.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
โ ๏ธ Do not discontinue any prescribed medication without consulting your treating physician. This test does not replace clinical management.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Active febrile illness or recent blood transfusion (within 2 weeks) may interfere with DNA quality; reschedule collection after recovery.
- Exclusion: Known bone marrow transplant recipient with donor chimerism โ interpretation may be compromised.
- Red Flag: Seek immediate medical attention if you experience unexplained high fever, severe recurrent infections, or sudden pallor and bruising โ these may indicate underlying hematologic emergency unrelated to the test itself.
Patient FAQ & Clinical Guidance
1. What does the RFX5 genetic test diagnose?
This test identifies RFX5 gene mutations causing Bare lymphocyte syndrome type II, a severe immunodeficiency (MHC class II deficiency).
2. How is the sample collected for this genetic test?
A blood draw or a single drop on an FTA card is collected by a DHA-licensed phlebotomist via our VIP mobile phlebotomy home collection service.
3. When will I receive my genetic test results?
Results are typically reported within 3 to 4 weeks after laboratory receipt, due to extensive sequencing and bioinformatic analysis.
UAE Regulatory & Data Privacy Adherence
This service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
DHA Facility License: 1143 | Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE
Accredited: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | RFX5 Gene (Bare Lymphocyte Syndrome Type 2) Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 Weeks (21โ28 Business Days) |
| Sample Type / Matrix | Peripheral Whole Blood (Venipuncture) or Dried Blood Spot (FTA Card) โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AMโ11 PM) |
| Methodology Used | Next-Generation Sequencing (NGS) with full exon coverage and copy number variation detection |
| ICD-10-CM Code | D82.1 (Bare Lymphocyte Syndrome) |
| LOINC Code | 21668-8 (Genetic testing, targeted mutation detection) |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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