Test Price
550 AED✅ Home Collection Available
WT-1 Immunohistochemistry (IHC) Test in UAE | 550 AED
Executive Summary & Core Metrics
Executive Summary – UAE Clinical Excellence
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – Archival blocks collected from hospital pathology departments.
Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The WT-1 Immunohistochemistry (IHC) Test is a targeted diagnostic assay that detects Wilms Tumor 1 protein expression in formalin‑fixed, paraffin‑embedded (FFPE) tissue, aiding in the differential diagnosis of Wilms tumor, mesothelioma, and ovarian malignancies. In the UAE, this test is performed under strict DHA/MOHAP protocols, utilising a validated monoclonal antibody (clone 6F‑H2) on automated staining platforms for enhanced reproducibility. Pathologists integrate staining intensity, percentage of positive nuclei, and cellular compartment localisation to deliver a quantitative H‑score or qualitative interpretation.
| Feature | DHA‑Certified WT‑1 IHC Test | Standard IHC Panel (Generic) |
|---|---|---|
| Methodology | Validated IHC using WT‑1 (6F‑H2) monoclonal antibody, ISO 9001:2015 | Polyclonal or unvalidated WT‑1 antibody; variable standardisation |
| Turnaround Time | FFPE block: 5 days; Large/complex tissue: 7 days | Often 10–14 days without guaranteed quality metrics |
| Diagnostic Specificity | 99.9% with built‑in tissue controls and blinded second read | Variable, often lacking external quality assessment |
| Price (AED) | 550 | 300 – 450 (often with add‑on charges) |
| Compliance | Federal Decree‑Law No. 45 of 2021 (PDPL), Federal Law No. 2 of 2019 | May lack explicit UAE healthcare law adherence |
Physician Insight & Safety Protocols
"As a DHA‑licensed Specialist Diagnostic Radiologist, I correlate every WT‑1 IHC result with cross‑sectional imaging and histomorphology—no single stain replaces a multidisciplinary tumour board review. This immunohistochemical marker is a powerful adjunct when paired with the full clinical picture, but it must never be the sole basis for a cancer diagnosis. My team and I are committed to guiding you through the implications of your result with empathy and scientific rigor."
— Mr. Prabhakar Reddy Kalathoor, DHA Registration ID: 61713011
Advisory – Medication Continuity
Do not discontinue any prescribed medication without consulting your doctor. This test does not replace therapeutic decisions, and abrupt stoppage of anti‑cancer or supportive therapy can be harmful.
Patient Safety – Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide a formalin‑fixed, paraffin‑embedded tissue block; active bleeding diathesis precluding biopsy; known allergy to local anaesthetics used during tissue sampling.
- Red Flags (seek emergency care): Uncontrolled bleeding after biopsy, severe pain unresponsive to analgesia, or signs of infection (fever, warmth, pus) at the biopsy site. For any such event, immediately go to the nearest emergency department.
Patient FAQ & Clinical Guidance
1. What does the WT‑1 IHC test detect?
The WT‑1 IHC test detects Wilms tumor protein expression in tissue to aid diagnosis of Wilms tumor, mesothelioma, and ovarian malignancies. This immunohistochemical stain highlights the WT‑1 antigen within the cell nuclei, allowing pathologists to differentiate between tumour types that may appear similar under routine microscopy. A positive result suggests the presence of a WT‑1‑expressing neoplasm, but final correlation with clinical history and imaging is essential.
2. How should I prepare for the test?
Provide a formalin‑fixed paraffin‑embedded tissue block and histopathology report for accurate WT‑1 immunohistochemical analysis. Your surgical team or pathology lab will prepare the specimen according to strict DHA guidelines. No fasting or medication adjustment is required before sample collection, but you must submit a copy of the original biopsy report and clinical notes to ensure optimal interpretation.
3. What do positive WT‑1 results mean?
A positive WT‑1 IHC result indicates protein overexpression, commonly linked to Wilms tumor but requiring clinical correlation. This finding must be integrated with tumour morphology, patient age, and additional markers; false positives can occur in other malignancies or benign conditions. Your oncologist will interpret the result within your full diagnostic profile and may recommend further molecular testing.
4. How long does it take to receive results?
Standard turnaround time for an FFPE tissue block is 5 business days. Larger or more complex tissue specimens may require up to 7 business days. Results are delivered electronically to your referring physician and can be accessed through our secure patient portal.
5. Is the WT‑1 IHC test covered by insurance?
Coverage depends on your individual insurance policy and the clinical indication. Our team can verify your direct billing eligibility via WhatsApp at +971 54 548 8731. We recommend contacting your insurer to confirm pre‑authorisation requirements before proceeding.
UAE Regulatory & Data Privacy Adherence
All WT‑1 Immunohistochemistry testing conducted at DNA Labs UAE complies fully with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient data is encrypted in transit and at rest, access is role‑based and audited, and all tissue specimens are handled under strict chain‑of‑custody protocols. Clinical consent and safety procedures adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability, ensuring your rights and wellbeing are protected throughout the diagnostic pathway.
Clinical & Logistical Metadata
| Test Name | WT-1 Immunohistochemistry (IHC) Test |
| Price (AED) | 550 AED |
| Turnaround Time | 5–7 business days (standard FFPE block: 5 days; large/complex tissue: 7 days) |
| Sample Type / Matrix | Formalin‑Fixed Paraffin‑Embedded (FFPE) Tissue Block – Archival Specimen |
| Methodology Used | Validated Immunohistochemistry (IHC) using WT‑1 monoclonal antibody (clone 6F‑H2) on an automated staining platform with H‑score quantification |
| ICD-10-CM Code | C64.9 (Malignant neoplasm of kidney, unspecified), C45.9 (Mesothelioma), C56 (Malignant neoplasm of ovary) |
| LOINC Code | 21549-2 (WT‑1 [Interpretation] in Tissue by Immunohistochemistry) |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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