Test Price
550 AED✅ Home Collection Available
MDM2 Immunohistochemistry (IHC) Test in UAE | 550 AED | DHA Licensed Reference Lab
Executive Summary & Core Metrics
✓Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
✓Specialized Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – temperature-controlled archival block collection from your hospital or clinic.
✓Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance for result interpretation.
✓Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The MDM2 Immunohistochemistry (IHC) Test detects MDM2 protein overexpression in tumor tissue, serving as a surrogate marker for gene amplification and helping distinguish dedifferentiated liposarcoma from benign mimics. This assay uses validated monoclonal antibodies on formalin-fixed paraffin-embedded (FFPE) sections with automated platform staining for reproducible diagnostic quality.
| Feature | Our MDM2 IHC Test | MDM2 FISH (Closest Alternative) |
|---|---|---|
| Methodology | Immunohistochemistry (IHC) – protein detection | Fluorescence in situ Hybridization (FISH) – gene level |
| Turnaround Time | 5–7 working days | 7–10 working days |
| Sensitivity | High for protein expression (correlates with amplification) | Gold standard for amplification detection |
| Sample | FFPE block / tumor in 10% formal-saline | FFPE block |
| Cost | 550 AED | Typically 750–1200 AED |
Physician Insight & Safety Protocols
🩺 Mr. Prabhakar Reddy Kalathoor | Specialist Diagnostic Radiology | DHA Registration ID: 61713011
“As a diagnostic radiologist, I regularly correlate MDM2 IHC results with imaging phenotypes to refine sarcoma subtyping and guide biopsy targeting. This protein-level assay provides rapid, cost-effective triage before confirmatory molecular testing. However, no single laboratory parameter should replace multidisciplinary discussion — always review findings with your treating oncologist and pathologist.”
Advisory: Medication & Pre-Procedure Guidance
⚠️ Medication Advisory
Do not discontinue any prescribed medication without consulting your physician. If a fresh biopsy is required prior to this test, inform your clinician about all medications, especially anticoagulants or antiplatelet agents. This laboratory test does not replace a comprehensive clinical assessment.
Exclusion Criteria & Emergency Red Flags
🚨 Safety Exclusion Warning & Emergency Red Flags
- Exclusion Criteria: Patients without a prior biopsy or surgical resection yielding tumor tissue cannot provide a specimen for this archival assay. The test is performed exclusively on existing FFPE blocks or formalin-saline specimens submitted by the referring facility.
- Red Flag Symptoms after biopsy (if recently performed): Seek immediate medical attention for severe pain, excessive bleeding, fever, or signs of infection at the biopsy site. This test does not triage acute conditions and is not intended for emergency use.
Patient FAQ & Clinical Guidance
1. What is the purpose of the MDM2 IHC test?
The MDM2 IHC test identifies overexpression of MDM2 protein in tumor cells, supporting the diagnosis of dedifferentiated liposarcoma and guiding targeted therapeutic decisions.
This immunohistochemical assay uses specific monoclonal antibodies to detect MDM2 protein on tissue sections. When positive and correlated with histomorphology, the result strongly suggests MDM2 gene amplification — a hallmark of certain sarcomas — and helps differentiate malignant lesions from benign adipocytic tumors.
2. How should I prepare for the MDM2 IHC test?
No special patient preparation is required; the assay is performed on previously collected tumor tissue.
The laboratory requires a formalin-fixed paraffin-embedded (FFPE) tissue block or a tumor sample in 10% formal-saline, accompanied by the histopathology report, biopsy site details, and relevant clinical history. If a fresh biopsy is needed, your physician will provide specific pre-procedure instructions regarding fasting or medication adjustments.
3. When can I expect my results and how will I receive them?
Your MDM2 IHC report will be available within 5–7 working days depending on tissue complexity, delivered through a secure channel.
Results are typically finalized within 5 days for standard biopsy specimens and up to 7 days for large or complex surgical resections. Reports are transmitted via encrypted email or through our secure patient portal, and include comprehensive histopathological interpretation. Our clinical team provides complimentary telephonic guidance upon request to help you contextualize the findings with your overall care plan.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance Framework:
- Data Protection: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – all patient health information is encrypted, access-controlled, and processed under lawful consent.
- Health Data Security: Adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring secure electronic transmission and storage of medical records.
- Clinical Safety & Consent: Operates under Federal Decree-Law No. 4 of 2016 on Medical Liability, guaranteeing informed consent protocols and professional accountability in all diagnostic procedures.
- Quality Management: ISO 9001:2015 accredited laboratory processes with rigorous internal and external quality control measures.
Clinical & Logistical Metadata
| Test Name | MDM2 Immunohistochemistry (IHC) Test |
| Price (AED) | 550 AED |
| Turnaround Time | 5–7 Working Days |
| Sample Type / Matrix | FFPE Tissue Block / Tumor in 10% Formalin-Saline (Archival Specimen – Secure Medical Courier Retrieval) |
| Methodology Used | Immunohistochemistry (IHC) – Automated Platform Protein Detection |
| ICD-10-CM Code | C49.9 (Malignant neoplasm of connective and soft tissue, unspecified) |
| LOINC Code | 94473-7 (MDM2 gene amplification [Presence] in Tissue by FISH) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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