Test Price
450 AEDโ Home Collection Available
Langerin (CD207) Immunohistochemistry Test in UAE
Executive Summary & Core Metrics
- Diagnostic Yield: 99.9% specificity for Langerhans cell histiocytosis via CD207 monoclonal antibody targeting.
- Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval โ strictly archival tissue transport; mobile phlebotomy is disabled for this assay.
- Clinical Guidance: Structured telephonic post-test consultation included for result interpretation and multidisciplinary care coordination.
- Insurance: Direct billing verification and pre-authorization support via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Langerin (CD207) immunohistochemistry test is a gold-standard tissue-based assay utilized for the precise identification of Langerhans cell histiocytosis (LCH) and other dendritic cell neoplasms. This automated IHC protocol employs a highly specific CD207 monoclonal antibody, enabling definitive subtyping of histiocytic disorders and guiding targeted oncological interventions. All processing is conducted within an ISO 9001:2015 accredited laboratory environment.
Comparative Clinical Advantage
| Feature | DNA Labs UAE (ISO 9001:2015) | Closest Alternative (Routine IHC Panel) |
|---|---|---|
| Target Specificity | Single-specificity CD207 monoclonal antibody with automated stainer | Broad panel (S100, CD1a) may lack CD207, yielding ambiguous results |
| Methodology | Fully automated IHC with ISO-certified multi-level quality control | Manual or semi-automated IHC with variable inter-observer reproducibility |
| Turnaround Speed | Tissue Biopsy: 5 days; Large Complex: 7 days | Often 7โ10 business days due to send-out testing |
| Reporting | Integrated digital report with concurrent histopathology and clinical history | Separate reports with delayed interdisciplinary integration |
Physician Insight & Safety Protocols
โAs a specialist overseeing oncologic diagnostics, I mandate that every Langerin IHC result is evaluated within the full clinical context, including histopathology architecture and correlative imaging. Isolated CD207 positivity demonstrates high sensitivity for LCH; however, definitive interpretation requires integration with the anatomical biopsy site and patient demographic data to avoid diagnostic misclassification. Initiation or modification of therapy must never occur based solely on this report without a structured interdisciplinary consultation.โ
โ Mr. PRABHAKAR REDDY KALATHOOR, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Medication & Clinical Advisory
Critical Clinical Advisory
Do not discontinue or alter any prescribed oncologic therapy without consulting your managing physician. This test provides complementary diagnostic data and must be interpreted alongside full clinical and radiographic findings. Always share the complete pathology report with your primary oncologist.
Exclusion Criteria & Emergency Red Flags
- Inability to provide sufficient FFPE tumor tissue (minimum 10% viable tumor content required).
- Patients with active bleeding diathesis who cannot safely undergo tissue biopsy.
- Red Flags: Seek immediate emergency care if you develop fever, uncontrolled pain, or signs of infection at the biopsy site.
- Not a screening test; must be ordered exclusively by a board-certified oncologist or surgical pathologist.
Patient FAQ & Clinical Guidance
1. What is the Langerin immunohistochemistry test used for?
Direct Answer Snippet: The Langerin IHC test detects CD207 protein expression to provide a definitive tissue diagnosis of Langerhans cell histiocytosis and related dendritic cell malignancies.
It is primarily applied to archival tumor tissue derived from bone, skin, or lymph nodes. A positive result indicates the presence of Langerin-positive cells, strongly supporting an LCH diagnosis and informing targeted oncologic management.
2. How long does it take to receive the test results in the UAE?
Direct Answer Snippet: Results for routine biopsies are reported within 5 days, while large or complex specimens require up to 7 days for complete histopathological correlation.
Our UAE-based ISO-certified laboratory processes all solid tissue specimens daily. Once the IHC staining and pathology review are finalized, you will receive a secure digital report and an optional telephonic consultation with our clinical team.
3. Does health insurance cover the Langerin test in Dubai and Abu Dhabi?
Direct Answer Snippet: Direct billing is accepted from all major insurers following a structured verification process via WhatsApp at +971 54 548 8731 to confirm coverage.
Coverage depends on your specific policyโs oncology and pathology benefits. Our patient support team facilitates pre-authorization, and the standard 450 AED fee is frequently reimbursed for DHA-regulated health plans.
UAE Regulatory & Data Privacy Adherence
Your data and clinical safety are protected under the highest UAE federal standards.
- Data Privacy: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Information Security: Adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical Safety & Consent: Governed by Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring informed consent and procedural safety.
Clinical & Logistical Metadata
| Test Name | Langerin (CD207) Immunohistochemistry |
| Price (AED) | 450 |
| Turnaround Time | 5 โ 7 Business Days |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block / Archival Surgical Slides |
| Methodology Used | Automated Immunohistochemistry (IHC) with CD207 Monoclonal Antibody |
| ICD-10-CM Code | C96.0 |
| LOINC Code | 72502-6 |
| DHA License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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