Test Price
550 AED✅ Home Collection Available
Immunohistochemistry (Smooth Muscle Actin – SMA) Tumor Marker Test in UAE | 550 AED
Executive Summary & Core Metrics
Executive Summary
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015–accredited protocols, fully compliant with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 on the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Specimen Type: Archival Tissue (formalin‑fixed paraffin‑embedded block or slides). Collection: Secure Medical Courier Solid Tissue Specimen Retrieval. Reporting: Dual‑consultant histopathology review (Oncologist + Surgical Pathologist) with free telephonic result interpretation. Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
Smooth Muscle Actin (SMA) immunohistochemistry is a critical differential stain used to identify smooth‑muscle differentiation in mesenchymal tumors (e.g., leiomyosarcoma) and to confirm myoepithelial origin in breast/salivary gland pathology. The test employs validated DHA‑compliant IHC on formalin‑fixed paraffin‑embedded tissue blocks, providing unambiguous cytoplasmic staining.
| Feature | Our SMA IHC Test (DNA Labs UAE) | Standard External Lab |
|---|---|---|
| Methodology | ISO 9001‑validated IHC with double‑antibody detection & automated stainer | Generic IHC, manual or semi‑automated, no external quality assurance |
| Turnaround Time | 5–7 days for large complex biopsies | 7–14 days |
| Accreditation | DHA/MOHAP, ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139), ISO 15189:2022 | None or unverified |
| Reporting | Dual‑consultant review (Oncologist + Surgical Pathologist) | Single technician/single pathologist |
| Price | 550 AED inclusive of courier retrieval & telephonic guidance | 600–900 AED (lab only, without courier) |
Physician Insight & Safety Protocols
Mr. Prabhakar Reddy Kalathoor (DHA Registration ID: 61713011), Specialist Diagnostic Radiology:
“Smooth Muscle Actin IHC is a cornerstone in oncologic pathology, but no single stain provides a diagnosis. It must be correlated with full clinical history, radiology, and a panel of other immunohistochemical markers (e.g., Desmin, Caldesmon) to avoid misinterpretation. Patients should always share the original histopathology report and exact biopsy site with our laboratory.”
Clinical Medication Advisory
⚠ Clinical Medication Warning
Do not discontinue any prescribed medication, chemotherapy, or immunotherapy without first consulting your treating physician.
- Red Flags – seek emergency care if after tissue biopsy you experience: bleeding that soaks the dressing, severe pain unrelieved by paracetamol, fever >38.5 °C, or signs of wound infection (redness, pus).
- This test is a complementary diagnostic tool; it is not a standalone cancer screening method.
Exclusion Criteria
- Exclusion criteria: specimen must be formalin‑fixed paraffin‑embedded tissue; fresh tissue, cytology smears, and decalcified bone biopsies may yield false‑negative or non‑specific results.
- Patients with known allergy to mouse monoclonal antibodies (rare) should notify the laboratory prior to testing.
Patient FAQ & Clinical Guidance
1. What conditions does the SMA IHC test help diagnose?
Smooth Muscle Actin IHC is a primary immunohistochemical stain used to identify smooth muscle differentiation in sarcomas and myoepithelial lesions. It is essential for classifying leiomyosarcomas, distinguishing them from other spindle cell tumors like gastrointestinal stromal tumors or fibrosarcomas, and for confirming myoepithelial cell involvement in breast and salivary gland carcinomas. The stain also plays a role in evaluating uterine smooth muscle tumors of uncertain malignant potential (STUMP).
2. Is the 550 AED price all-inclusive for this test, including courier retrieval?
The 550 AED fee covers all laboratory processing and DHA-licensed histopathology reporting, including VAT and complimentary secure courier retrieval of your archival tissue specimen. Patients receive a single comprehensive invoice with no hidden charges. For insurance direct billing, our team verifies coverage before the visit via WhatsApp +971 54 548 8731; if your policy is accepted, you may only pay the co‑payment.
3. How should I prepare for the SMA IHC?
No fasting or dietary restrictions are required; simply provide the original histopathology report, exact biopsy site, and complete clinical history. The laboratory must receive formalin‑fixed tissue (10% neutral buffered formalin) or a paraffin block shipped at room temperature. Our courier will collect the specimen under ambient conditions, and you can continue all regular medications unless instructed otherwise by your physician.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Health Information Protection
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, stored securely, and never shared without explicit consent. Clinical testing and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory is licensed by the Dubai Health Authority (DHA Facility License Number: 1143) and operates under the highest ethical and regulatory standards.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry (Smooth Muscle Actin – SMA) Tumor Marker |
| Price (AED) | 550 |
| Turnaround Time | 5–7 business days |
| Sample Type / Matrix | Formalin‑fixed paraffin‑embedded (FFPE) tissue block or slides |
| Methodology Used | Immunohistochemistry (IHC) with automated stainer, double‑antibody detection |
| ICD-10-CM Code | C49.9 |
| LOINC Code | 34758-7 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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