Test Price
550 AED✅ Home Collection Available
PAX-5 Immunohistochemistry (IHC) Test – Lymphoma Classification, Dubai
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – archival FFPE blocks handled via temperature-controlled courier. Hospital extraction only.
Clinical Guidance: Complimentary Telephonic Post-Test Result Interpretation by our specialist.
Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The PAX-5 immunohistochemistry stain detects the B-cell-specific activator protein (BSAP) in formalin-fixed, paraffin-embedded (FFPE) tissue sections. It is essential for confirming B-cell lineage in lymphomas and leukemias, aiding accurate subtyping of diffuse large B-cell lymphoma, follicular lymphoma, and precursor B-cell neoplasms. The test is performed on a fully validated Leica Bond-max automated platform using a monoclonal antibody clone (specific to PAX5).
| Feature | Our PAX-5 IHC Test (DHA-Licensed) | Closest Alternative |
|---|---|---|
| Precision | Monoclonal antibody, standardized automated staining (Leica Bond-max) | Polyclonal or manual stains, higher variability |
| Methodology | Fully validated IHC on FFPE, DHA-licensed and ISO-certified lab | IHC on non-validated platforms or flow cytometry only |
| Turnaround | 5–7 business days (from block receipt); results reported by 6 PM daily | 7–14 days typical |
Physician Insight & Safety Protocols
“PAX-5 is a cornerstone marker for B-cell lineage determination. A positive stain must be correlated with morphology and a panel of markers (CD20, CD79a, TdT, BCL6) to precisely subclassify lymphomas. Single-marker interpretation can misguide therapy decisions.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Advisory Notice
Do not discontinue or alter any prescribed medication without consulting your treating physician. This test is for tissue-based diagnosis; it does not evaluate blood levels of therapeutic drugs.
Exclusion Criteria & Emergency Red Flags
- Patient age below 18 years without legal guardian consent (per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Inadequate tissue specimen (necrotic, decalcified, or core <2mm) may yield false-negative results.
- Seek immediate emergency care if you develop high-grade fever, uncontrolled bleeding, or sudden neurological symptoms post-biopsy.
- Inform our laboratory of any known anaphylaxis to latex or iodine dyes before specimen collection.
Patient FAQ & Clinical Guidance
1. What does a positive PAX-5 result mean for my diagnosis?
A positive PAX-5 stain confirms B-cell lineage in the tumor cells, which is essential for correctly classifying lymphomas like diffuse large B-cell lymphoma or chronic lymphocytic leukemia. It must be interpreted alongside your complete histopathology report by your oncologist.
2. How is the sample collected, and is it painful?
The test requires a small piece of tumor tissue obtained via biopsy (core needle, incisional, or excisional). Local anesthetic is used to minimize discomfort. The specimen is then formalin-fixed and paraffin-embedded. Our service provides Secure Medical Courier Solid Tissue Specimen Retrieval from the hospital where your biopsy is performed.
3. Can I use this test to monitor treatment response?
PAX-5 IHC is primarily a diagnostic marker and not routinely used alone for monitoring. Loss of PAX-5 expression in a previously positive tumor may indicate clonal evolution or transformation, but standard follow-up involves imaging, clinical evaluation, and repeat biopsy when clinically indicated.
UAE Regulatory & Data Privacy Adherence
Data Protection: All patient health information is processed in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and in accordance with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Results are encrypted and shared only with the ordering physician via secure channels.
Medical Liability: Clinical procedures and patient consent follow the provisions of Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | PAX-5 Immunohistochemistry (IHC) – Tissue |
| Price (AED) | 550 |
| Turnaround Time | 5–7 Business Days |
| Sample Type / Matrix | FFPE Tissue Block / Archival Solid Tissue Specimen – Hospital Extraction Only |
| Methodology Used | Automated Immunohistochemistry (IHC) on Leica Bond-max platform using monoclonal anti-PAX5 antibody |
| ICD-10-CM Code | C85.9 (Non-Hodgkin lymphoma, unspecified) |
| LOINC Code | 104594-9 (PAX5 [Presence] in Tissue by Immune stain) |
| DHA Facility License & Address | DHA License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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