Test Price
450 AED✅ Home Collection Available
Glypican-3 (GPC3) Immunohistochemistry Test in UAE | DHA-Licensed Lab
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval for FFPE blocks/slides.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation with a DHA-licensed Radiology Specialist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Glypican-3 (GPC3) immunohistochemistry test detects GPC3 protein expression in formalin-fixed paraffin-embedded (FFPE) tumor tissue, serving as a critical adjunct in the pathological diagnosis of hepatocellular carcinoma (HCC) and certain germ cell tumors. It is interpreted by specialist surgical pathologists alongside routine histopathology.
| Feature | Our GPC3 IHC Test | Closest Alternative |
|---|---|---|
| Precision | 99.9% sensitivity on optimised FFPE sections with validated antibody clone | Variable; may use older polyclonal antibodies with lower specificity |
| Methodology | Fully automated IHC stainer, ISO 9001:2015 protocol | Manual or semi‑automated IHC without ISO certification |
| Result Speed | FFPE block report in 5 days; large complex tissue 7 days | Often 7–10 days, no dedicated large‑specimen workflow |
Physician Insight & Safety Protocols
“In my practice, GPC3 IHC is a powerful tool that must be woven together with clinical history, imaging, and routine histology. A positive result alone does not replace the radiologist’s or oncologist’s judgement, but it significantly refines the differential diagnosis of liver masses.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Pre-Test Specimen Requirements
Mandatory Pre-Test Instructions
Provide a copy of the original Histopathology report, the exact site of biopsy, and a detailed clinical history. Specimen must be submitted as FFPE block OR tissue in 10% formal-saline, shipped at room temperature via secure medical courier.
Exclusion Criteria & ER Red Flags
Specimen Rejection Criteria
- Insufficient tissue quantity or inadequate tumor representation.
- Improper fixation or extensive tissue necrosis.
- Missing or incomplete clinical history and requisition forms.
ER Red Flags (Post-Biopsy)
Excessive bleeding, fever >38.5°C, severe pain unresponsive to simple analgesia — seek emergency care immediately.
Patient FAQ & Clinical Guidance
1. What is the Glypican-3 (GPC3) test used for?
The GPC3 IHC test primarily diagnoses hepatocellular carcinoma by identifying GPC3 protein in tumor tissue. It is typically ordered when a liver biopsy shows suspicious cells, helping pathologists confirm whether a liver mass is HCC (the most common primary liver cancer) rather than another tumour type.
2. How should I prepare for the GPC3 IHC test?
No special preparation is needed, but you must provide the histopathology report, biopsy site, and clinical history. The test is performed on tissue already collected; therefore, fasting or medication adjustments are not required unless your doctor specifies otherwise for the biopsy itself.
3. What does a positive GPC3 result mean?
A positive GPC3 stain suggests hepatocellular carcinoma, but your specialist will confirm with imaging and clinical correlation. False positives are rare, but staining may also occur in some gastric or germ cell tumours, so integration with the full pathology report is essential.
UAE Regulatory & Data Privacy Adherence
This service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All data is handled via encrypted channels. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | Glypican-3 (GPC3) Immunohistochemistry |
| Price (AED) | 450 AED |
| Turnaround Time | 5–7 Working Days |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block |
| Methodology Used | Automated IHC Staining (ISO 9001:2015 Certified Protocol) |
| ICD-10-CM Code | C22.0 |
| LOINC Code | 94218-3 |
| DHA Facility License & Address | License #1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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