Test Price
550 AED✅ Home Collection Available
Immunohistochemistry D2-40 (Podoplanin) Test in UAE | 550 AED | DHA Licensed Lab
Executive Summary & Core Metrics
The Immunohistochemistry D2-40 (Podoplanin) assay is a high-specificity IHC stain targeting podoplanin, a lymphatic endothelial marker used for diagnosing lymphatic tumors and evaluating lymphovascular invasion. This test delivers 99.9% diagnostic sensitivity through ISO-accredited processing and standardized antigen retrieval protocols.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval from any GCC hospital or clinic.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by our specialist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
Immunohistochemistry D2-40 utilizes a monoclonal antibody directed against podoplanin, a transmembrane glycoprotein constitutively expressed on lymphatic endothelial cells. The stain distinguishes lymphatic vessels from blood vessels in formalin-fixed, paraffin-embedded (FFPE) tissue sections, providing critical information for diagnosing lymphangiomas, Kaposi sarcoma, and assessing lymphovascular invasion in malignant neoplasms. The automated IHC platform ensures reproducible, high-contrast staining with standardized antigen retrieval, enabling confident interpretation by our pathology team.
| Feature | Our Test | Closest Alternative (Standard IHC) |
|---|---|---|
| Precision | ISO 9001:2015 validated D2-40 antibody, 99.9% sensitivity | Variable antibody clone, no ISO validation |
| Method | Automated IHC with standardized antigen retrieval protocol | Manual or generic IHC without protocol harmonization |
| Speed | FFPE Block: 5 days; Large complex: 7 days | Often 7–10 days, no prioritization |
| Clinical Integration | Telephonic guidance & multidisciplinary review | Report only, no physician consultation |
Physician Insight & Safety Protocols
“As a diagnostic radiologist, I emphasize that D2-40 positivity must always be correlated with morphological features and the full clinical picture. Patients should never interpret immunohistochemical results in isolation; a specialist review is essential to avoid diagnostic errors and ensure appropriate management.” — Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Medication Advisory
Important Medication Advisory
Do not discontinue prescribed medication without consulting your doctor. Immunohistochemical results are not standalone diagnostic tools; therapy changes should be based on comprehensive clinical evaluation and multidisciplinary input.
Safety Exclusion Criteria & ER Red Flags
- Exclusion: Inadequate tissue fixation (non-formalin-fixed specimens) may yield false negative results.
- Exclusion: Patients on anticoagulants with active bleeding at biopsy site require clearance before tissue collection.
- Red Flag: Rapid lesion growth, ulceration, or sudden pain — seek immediate oncological evaluation.
- Red Flag: If D2-40 positive in an unexpected context (e.g., non-endothelial tumor), urgent specialist referral is required.
Note: This test is not indicated for screening; it is a specialized immunohistochemical assay requiring a prior histopathology report.
Patient FAQ & Clinical Guidance
1. What is the D2-40 test used for?
D2-40 immunohistochemistry specifically stains podoplanin, a marker for lymphatic endothelial cells, to diagnose lymphangiomas, Kaposi sarcoma, and assess lymphovascular invasion in cancers. It is performed on FFPE tissue sections and must be interpreted alongside morphological features and clinical history.
2. How should I prepare for the D2-40 test?
You need to provide a tissue sample (biopsy or surgical specimen) fixed in formalin, along with a copy of your histopathology report and clinical history for accurate interpretation. No special diet or medication adjustment is required.
3. When will I receive my results?
Turnaround time is 5 days for standard FFPE blocks and 7 days for large complex tissue biopsies, ensuring thorough immunohistochemical staining and pathologist review. Results are delivered electronically with telephonic guidance available.
UAE Regulatory & Data Privacy Adherence
Compliance & Data Protection Framework
All laboratory processes strictly adhere to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. ISO 9001:2015 Certified Lab (Cert: INT/EGQ/2509DA/3139). DHA Facility License: 1143.
Clinical & Logistical Metadata
| Test Name | Immunohistochemistry D2-40 (Podoplanin) |
| Price (AED) | 550 |
| Turnaround Time | 5–7 Business Days |
| Sample Type / Matrix | FFPE Tissue Block / Biopsy Slides (Archival Specimen) |
| Methodology Used | Immunohistochemistry (IHC) with Monoclonal D2-40 Antibody, Automated Platform |
| ICD-10-CM Code | D18.1, C46.9, C49.9 |
| LOINC Code | 75174-1 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE — DNA Labs UAE |
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