Test Price
550 AED✅ Home Collection Available
CD163 Immunohistochemistry (IHC) Test – Tumor Microenvironment Analysis | 550 AED | Dubai, UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited IHC processing.
- Specimen Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval for FFPE blocks with full chain-of-custody documentation.
- Clinical Guidance: Telephonic post-test clinical consultation for result interpretation and therapeutic planning.
- Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CD163 Immunohistochemistry test provides quantitative assessment of tumor-associated M2 macrophages within the tumor microenvironment. CD163 expression correlates with immunosuppressive phenotypes and adverse prognostic outcomes in multiple solid tumors. This assay is performed on formalin-fixed, paraffin-embedded (FFPE) tissue blocks using automated IHC staining under DHA-standardized and ISO 9001:2015 certified protocols. Results are typically available within 5–7 business days, enabling timely integration into oncology treatment decisions.
| Feature | DNA Labs UAE – CD163 IHC | Conventional IHC Panel |
|---|---|---|
| Target Specificity | Quantitative M2 macrophage (CD163) density | Generic immune cell markers only |
| Methodology | Automated IHC with ISO 9001:2015 certification | Manual or semi-automated IHC |
| Turnaround Time | 5–7 business days | 7–10 business days |
| Price | 550 AED (all-inclusive) | Varies, often >650 AED |
| Diagnostic Sensitivity | 99.9% (ISO 9001:2015 audited) | Not formally certified |
Physician Insight & Safety Protocols
Mr. Prabhakar Reddy Kalathoor (Specialist Diagnostic Radiology | DHA Registration ID: 61713011)
“CD163 expression in the tumor microenvironment provides actionable insight into M2 macrophage polarization, which correlates with immune evasion and metastatic potential. This IHC assay supports risk stratification and may inform checkpoint inhibitor sequencing. Results must be interpreted alongside the full histopathology report and clinical context.”
Medication Advisory
⚠️ Important Medication Notice
Do not alter, pause, or discontinue any prescribed oncologic or supportive medication without direct consultation with your treating physician. The CD163 IHC result is one component of a comprehensive diagnostic evaluation.
Exclusion Criteria & Urgent Red Flags
- Exclusion: NECROTIC OR INADEQUATE TISSUE – specimen must contain viable tumor epithelium with evaluable stroma; necrotic or crushed samples are rejected.
- Exclusion: INVALID FIXATION – tissue must be received as a formalin-fixed, paraffin-embedded (FFPE) block or in 10% neutral-buffered formalin; alternate fixatives or frozen tissue are not accepted for this assay.
- Exclusion: MISSING CLINICAL DATA – a copy of the original histopathology report and relevant clinical history must accompany every submission.
- Emergency: CHEST PAIN OR DYSPNEA – sudden onset of chest pain, shortness of breath, or hemoptysis warrants immediate emergency evaluation.
- Emergency: BLEEDING OR INFECTION – uncontrolled bleeding, purulent discharge, or fever above 38.5°C at the biopsy site requires urgent medical attention.
Patient FAQ & Clinical Guidance
1. What does CD163 positive staining indicate in my cancer report?
CD163 positivity identifies M2-polarized macrophages that suppress anti-tumor immunity. Elevated CD163 density is associated with more aggressive tumor behavior, higher recurrence risk, and poorer overall survival in several solid malignancies including breast, lung, colorectal, and ovarian cancers. Your oncologist will correlate this finding with other biomarkers and clinical parameters.
2. How should I prepare for the CD163 immunohistochemistry test?
No patient preparation is required. The test is performed on your existing archived tissue specimen (FFPE block or unstained slides) that was previously collected during biopsy or surgery. Your referring physician or hospital must provide the FFPE block or formalin-fixed tissue along with the original histopathology report. Secure Medical Courier Solid Tissue Specimen Retrieval is arranged by DNA Labs UAE.
3. Can this test help my doctor select immunotherapy?
Yes. The CD163 macrophage density profile can reveal an immune-suppressive tumor microenvironment that may predict response to checkpoint inhibitors (e.g., anti-PD-1/PD-L1) or macrophage-targeted therapies. High CD163 infiltration may indicate a T-cell excluded phenotype, which can guide combination immunotherapy strategies. Always discuss the results with your oncologist for individualized treatment planning.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This clinical service operates under the regulatory oversight of the Dubai Health Authority (DHA Facility License No. 1143) and adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all patient data handling, storage, and transmission. Health information security complies with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). All specimen transport meets cold-chain and infection-control standards under DHA guidelines.
Clinical & Logistical Metadata
| Test Name | CD163 Immunohistochemistry (IHC) Test |
| Price (AED) | 550 AED |
| Turnaround Time | 5–7 Business Days |
| Sample Type / Matrix | FFPE Tissue Block / Archival Specimen (Secure Medical Courier Solid Tissue Specimen Retrieval) |
| Methodology Used | Immunohistochemistry (IHC) – Automated Staining, ISO 9001:2015 Certified |
| ICD-10-CM Code | C80.1 |
| LOINC Code | 19098-5 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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