Test Price
450 AED✅ Home Collection Available
IgG4 Immunohistochemistry (IHC) Test in UAE | 450 AED | DHA Licensed Lab
Executive Summary & Core Metrics
DNA Labs UAE offers the gold-standard IgG4 Immunohistochemistry (IHC) test for the precise diagnosis of IgG4-related disease. Our fully accredited pathology laboratory (ISO 9001:2015 – Cert: INT/EGQ/2509DA/3139) provides 99.9% diagnostic sensitivity through automated IHC staining protocols. We facilitate Secure Medical Courier Solid Tissue Specimen Retrieval for archival FFPE blocks and biopsy slides. All results are interpreted by DHA-licensed specialist pathologists and include post-test telephonic clinical guidance. Direct insurance billing assistance is available via WhatsApp at +971 54 548 8731.
99.9% Sensitivity
ISO accredited IHC staining
Archival Tissue Retrieval
Secure medical courier
Post-Test Clinical Guidance
DHA-licensed pathologist
Insurance Billing Verification
WhatsApp +971 54 548 8731
Test Overview & Methodology
The IgG4 Immunohistochemistry (IHC) test is a specialized tissue staining technique that identifies IgG4-positive plasma cells within biopsy specimens, enabling precise diagnosis of IgG4-related disease. This test is performed on archival tissue specimens using validated monoclonal antibodies and automated staining platforms to ensure reproducibility and diagnostic accuracy.
| Parameter | Our IgG4 IHC Test | Serum IgG4 Blood Test |
|---|---|---|
| Test Type | Tissue Immunohistochemistry | Serum Quantitative Assay |
| Diagnostic Target | IgG4+ plasma cells in biopsy | Circulating IgG4 levels |
| Sensitivity / Specificity | High specificity for tissue diagnosis | Moderate; elevated in many conditions |
| Turnaround Time | 5–7 working days | 1–2 days |
| Sample Requirement | FFPE block or 10% formalin-saline tissue + histopathology report | Venous blood sample |
Physician Insight & Safety Protocols
“As a Specialist Diagnostic Radiologist, I emphasize that IgG4 immunohistochemistry results must be correlated with the morphological pattern, clinical context, and any relevant serology. A positive stain alone is not equivalent to a definitive diagnosis of IgG4-related disease; it requires integration with histomorphological criteria and exclusion of mimics. Always discuss the report with your treating physician before making any change to your treatment.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Medication Safety Advisory
Do not discontinue or alter any prescribed medication without prior consultation with your treating physician. The interpretation of IgG4 IHC results should always be integrated with clinical and radiological findings for accurate disease management.
Safety Exclusion Criteria & Emergency Red Flags
- Absolute contraindication: severe coagulopathy or active skin infection at the intended biopsy site.
- Seek immediate medical attention if you experience persistent bleeding lasting more than 30 minutes from the biopsy site, fever exceeding 38°C, or severe pain unresponsive to simple analgesics.
- Pregnant or paediatric patients must follow institution-specific biopsy protocols under specialist supervision, in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the IgG4 immunohistochemistry test used for?
The IgG4 IHC test detects an abnormal number of IgG4-positive plasma cells in tissue to confirm IgG4-related disease. This test is performed on biopsy material (tumor or inflammatory tissue) using highly specific antibodies that bind IgG4, and the distribution of stained cells is interpreted by a DHA-licensed pathologist. A positive result, together with characteristic histomorphology, strongly supports conditions such as autoimmune pancreatitis, retroperitoneal fibrosis, or IgG4-related sclerosing cholangitis.
2. How should I prepare for the IgG4 IHC tissue test?
You must provide a copy of the original histopathology report, biopsy site details, and relevant clinical history. Fasting is not required for the biopsy itself, but you should follow your doctor’s pre-procedure instructions. The specimen must be submitted as a formalin-fixed paraffin-embedded (FFPE) block or tissue in 10% neutral buffered formalin-saline, shipped at room temperature via our secure medical courier system. The accompanying histopathology report, biopsy site details, and clinical summary are essential for accurate interpretation and must not be omitted.
3. How long do results take and what is the cost?
The IgG4 IHC test report is available within 5–7 working days depending on sample complexity. For FFPE blocks, reports are issued within 5 days; tissue biopsies require 5 days; large complex specimens take up to 7 days. The total fee is 450 AED, inclusive of technical and professional components. All processing is ISO 9001:2015 certified, and you can receive telephonic post-test clinical guidance from our DHA-licensed pathologists at no extra charge.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data, diagnostic results, and archival tissue specimens are handled under strict confidentiality protocols with encrypted storage and access control. Our laboratory operates under DHA Facility License Number 1143 and complies with all regulatory standards for diagnostic testing and clinical data governance in the Emirate of Dubai.
Clinical & Logistical Metadata
| Test Name | IgG4 Immunohistochemistry (IHC) |
| Price (AED) | 450 |
| Turnaround Time | 5–7 Working Days |
| Sample Type / Matrix | Archival Tissue Specimen (FFPE Block or Biopsy Slides) |
| Methodology Used | Automated Immunohistochemistry (IHC) Staining |
| ICD-10-CM Code | M35.0 |
| LOINC Code | 21952-8 |
| DHA Facility License & Address | License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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