Test Price
600 AED✅ Home Collection Available
HHV-8 (LNA-1) Immunohistochemistry (IHC) Test in UAE | 600 AED | DHA Licensed | DNA Labs UAE
Executive Summary & Core Metrics
- Diagnostic Sensitivity: Up to 99.9% accuracy using ISO-certified immunohistochemistry protocols.
- Specimen Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – FFPE blocks or slides are collected by certified medical courier; home phlebotomy is not applicable for this tissue-based assay.
- Post-Test Support: Telephonic clinical guidance to help interpret results.
- Insurance: Direct coverage verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The HHV-8 IHC test is a gold-standard immunohistochemical assay that detects the latent nuclear antigen-1 (LNA-1) of Human Herpesvirus 8 (HHV-8) in formalin-fixed, paraffin-embedded (FFPE) tumor tissue. It is essential for the definitive diagnosis of HHV-8-associated malignancies, including Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman disease.
| Feature | Our Test (HHV-8 IHC) | Closest Alternative (HHV-8 PCR) |
|---|---|---|
| Precision / Specificity | 99.9% specificity for LNA-1; directly visualizes infected cells in tissue context | High sensitivity for viral DNA but lacks spatial localization; may detect latent non-pathogenic virus |
| Methodology | Immunohistochemistry with monoclonal antibody (LN53) on FFPE sections | Real-time PCR or nested PCR detecting HHV-8 DNA |
| Turnaround Time | 5–7 working days | 3–5 working days |
Physician Insight & Safety Protocols
Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology (DHA License: 61713011) emphasizes: “A positive HHV-8 immunohistochemical stain must always be correlated with the patient’s clinical presentation, imaging findings, and histopathological morphology to confirm an HHV‑8‑driven malignancy. This test is a powerful adjunct, not a standalone screening tool, and its interpretation requires integration into the full diagnostic work‑up. Please discuss all results with your treating oncologist before considering any change in management.”
Advisory Notice
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & ER Red Flags
- Exclusion Criteria: Patients with uncorrected bleeding diathesis, active infection at the biopsy site, known allergy to local anesthetics, or inability to provide informed consent (minors require guardian consent as per Federal Decree-Law No. 4 of 2016 on Medical Liability). Pregnancy is a relative contraindication – consult your physician.
- Emergency Red Flags (seek immediate medical attention): Rapidly enlarging or painful mass at any site, sudden severe pain or bleeding from the biopsy site, signs of systemic infection (fever >38.5°C, chills), or any unexpected neurological symptoms following the procedure.
Patient FAQ & Clinical Guidance
1. What is the HHV-8 IHC test used for?
The HHV-8 immunohistochemistry identifies the LNA-1 protein in tumor cells to diagnose Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman disease.
2. How is the sample collected?
A tumor tissue sample is obtained via biopsy or surgery, fixed in formalin, and embedded in paraffin for immunohistochemical staining. The FFPE block or slides are then securely couriered to our laboratory.
3. How long does it take to get results?
Results are typically available within 5 to 7 working days after the specimen reaches our ISO-certified laboratory.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is handled confidentially and in full compliance with Dubai Health Authority (DHA) regulations. Our DHA facility license number is 1143, and our laboratory premises are located at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | HHV-8 (LNA-1) Immunohistochemistry (IHC) |
| Price (AED) | 600 AED |
| Turnaround Time | 5–7 working days |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block or Slides (Archival Specimen) |
| Methodology Used | Immunohistochemistry with monoclonal antibody (LN53) on FFPE sections |
| ICD-10-CM Code | C46.9 (Kaposi sarcoma, unspecified site) |
| LOINC Code | 74917-0 (Human herpesvirus 8 LNA-1 [Presence] in Tissue by Immune stain) |
| DHA Facility License & Laboratory Address | DNA Labs UAE | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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