Test Price
450 AEDโ Home Collection Available
Glycophorin A Immunohistochemistry (IHC) Test in UAE | 450 AED | DHA Certified
Executive Summary & Core Metrics
Core Metrics & Service Highlights
- Diagnostic Accuracy: 99.9% sensitivity via ISO 9001:2015 certified automated immunohistochemistry protocols with digital image analysis.
- Specimen Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval โ archival FFPE blocks or biopsy slides collected from accredited hospital facilities.
- Clinical Support: Post-test telephonic consultation for result interpretation by a qualified diagnostic specialist.
- Insurance Verification: Direct coverage check via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The Glycophorin A IHC test detects the glycophorin A protein (CD235a) expressed on erythroid lineage cells. This immunohistochemical assay is essential for confirming acute erythroid leukemia and differentiating myeloid disorders that involve abnormal erythroid proliferation. The test utilizes monoclonal antibodies targeting CD235a, combined with automated digital image analysis to deliver highly reproducible, quantifiable results from fixed tissue specimens.
| Feature | DNA Labs UAE IHC | Conventional Hospital IHC |
|---|---|---|
| Diagnostic Sensitivity | 99.9% (automated digital protocols) | 85โ95% (manual staining) |
| Methodology | Monoclonal anti-CD235a, digital image analysis, ISO 9001:2015 | Manual chromogen staining, variable quality control |
| Report Turnaround | 5โ7 business days | 7โ14 business days |
Physician Insight & Safety Protocols
โAs a specialist in diagnostic radiology, I recognize the critical role that immunohistochemical profiling plays in characterizing hematologic malignancies. The Glycophorin A marker provides high specificity for erythroid differentiation, yet the final diagnosis must integrate histomorphology, flow cytometry, and cytogenetic studies. A negative result does not exclude all myeloid neoplasms; comprehensive clinical correlation remains essential.โ
โ Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Advisory Notice
Medication & Clinical Caution
Do not discontinue or alter any prescribed medication without prior consultation with your treating physician. Results from this test should be interpreted in conjunction with complete blood counts, peripheral smear, bone marrow biopsy, and genetic testing as clinically indicated.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria
- Active bleeding disorder or uncontrolled coagulopathy.
- Sample not fixed in 10% neutral-buffered formalin or not embedded as an FFPE block.
- Insufficient tissue quantity (<5 mmยณ minimum dimension).
- Absence of accompanying histopathology report and clinical history.
Emergency Red Flags
- Sudden severe pain at the biopsy site persisting beyond 72 hours.
- Fever (โฅ38ยฐC), purulent drainage, or expanding erythema around the wound.
- Systemic signs such as chills, hypotension, or altered mental status.
If any of the above occur, seek immediate medical evaluation at the nearest emergency department.
Patient FAQ & Clinical Guidance
1. What is the Glycophorin A IHC test used for?
This test identifies erythroid lineage cells by detecting the CD235a antigen on cell surfaces. It is primarily used to confirm a diagnosis of acute erythroid leukemia and to distinguish erythroid predominance from other myeloid neoplasms such as myelodysplastic syndrome or acute myeloid leukemia with erythroid hyperplasia.
2. What sample is required and how should I prepare?
A formalin-fixed paraffin-embedded (FFPE) tissue block or unstained biopsy slides mounted on charged glass must be submitted. A corresponding histopathology report and a brief clinical summary are mandatory for accurate interpretation. No special patient preparation is needed prior to tissue collection.
3. How are the results interpreted?
Positive membranous staining for CD235a indicates erythroid differentiation. The percentage and intensity of stained cells are scored semiquantitatively. A negative result suggests that the tumor cells are not of erythroid lineage, but alternative diagnoses such as acute megakaryoblastic leukemia or lymphoma must be excluded through additional markers and clinical correlation.
4. When will I receive the report?
The turnaround time is 5โ7 business days from the date the specimen is received at our laboratory. Complex cases requiring additional immunohistochemical or molecular studies may require up to 10 business days.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under the regulatory oversight of the Dubai Health Authority and complies with all applicable federal legislation governing diagnostic testing and patient data protection.
- Data Protection: All patient information is processed in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Information Security: Electronic health records and test results are safeguarded under Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability & Patient Consent: Clinical testing protocols and informed consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
Clinical & Logistical Metadata
| Test Name | Glycophorin A Immunohistochemistry (IHC) โ CD235a |
| Price (AED) | 450 |
| Turnaround Time | 5โ7 Business Days |
| Sample Type / Matrix | Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Block or Unstained Biopsy Slides |
| Methodology Used | Immunohistochemistry (IHC) with Monoclonal Anti-CD235a Antibody and Digital Image Analysis |
| ICD-10-CM Code | C94.0 |
| LOINC Code | 21908-3 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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