Test Price
2,800 AED✅ Home Collection Available
IL7R Gene Severe Combined Immunodeficiency, T-Cell Negative, B-Cell/NK-Cell Positive Type Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين IL7R لنقص المناعة المشترك الشديد السلبي للخلايا التائية والإيجابي للخلايا البائية والقاتلة الطبيعية في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary / ملخص تنفيذي
Accuracy Guarantee: 99.9% diagnostic sensitivity with next-generation sequencing (NGS) processed in our ISO 9001:2015‑certified genetic laboratory.
Premium Logistics: Paid hospital‑grade home collection via ISO‑certified cold‑chain transport (8 AM‑11 PM daily) and VIP mobile phlebotomy. Samples preserved on DNA FTA cards, extracted DNA, or whole blood.
Clinical Guidance: Telephonic post‑test clinical interpretation by a genetic counsellor and access to a board‑certified immunologist.
Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
اختبار الحمض النووي لتحديد طفرات جين IL7R المؤدية لنقص المناعة المشترك الشديد السلبي للخلايا التائية والإيجابي للخلايا البائية والخلايا القاتلة الطبيعية، بدقة تشخيصية تصل إلى 99.9% تحت إرشادات هيئة الصحة بدبي لعام 2026. تشمل الخدمة سحب العينات المنزلية المعتمد والنقل المبرد وفق معايير الآيزو، مع استشارة وراثية بعد الفحص.
Test Overview
This advanced genetic test analyses the entire coding region of the IL7R gene using next‑generation sequencing (NGS) to identify pathogenic variants causing severe combined immunodeficiency (SCID), T‑cell negative, B‑cell/natural killer cell‑positive phenotype. (تحليل شامل لجين IL7R لكشف طفرات نقص المناعة المشترك الشديد بدقة عالية.) Turnaround time is 3‑4 weeks.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Diagnostic Precision | 99.9% sensitivity; detects single‑nucleotide variants, indels, and copy‑number changes across entire coding region | Focused hotspots only; may miss deep intronic or large deletions |
| Methodology | Illumina NGS platform with bioinformatic alignment, validated by Sanger confirmation | Capillary electrophoresis; limited scalability |
| Turnaround Speed | 3–4 weeks (expedited reporting available) | 6–8 weeks typical |
Physician Insight & Safety Protocol
“Genetic testing for IL7R‑related SCID is a life‑saving investigation. Results must be correlated with lymphocyte subsets and clinical history. A negative test does not exclude other forms of SCID; similarly, a variant of uncertain significance warrants familial segregation studies. Always consult a clinical immunologist before making therapeutic decisions.” – Dr. PRABHAKAR REDDY (DHA License 61713011)
Medication Warning
Do not discontinue any prescribed immunosuppressive or antimicrobial medication without explicit instruction from your treating physician. Genetic test results do not replace ongoing clinical management.
Exclusion Criteria & Emergency Red Flags
- The test cannot be performed on haemolysed or severely lipaemic blood samples.
- Patients who have received allogeneic haematopoietic stem cell transplant within the last 90 days may have donor DNA interference.
- If the patient develops acute respiratory distress, persistent fever >38.5°C, or signs of severe infection while awaiting results, seek emergency care immediately and inform the laboratory.
- Individuals with known maternal cell contamination in previous genetic tests require a buccal swab or purified DNA from a hair root.
Patient FAQ & Clinical Guidance
1. What does this IL7R gene test detect?
This test identifies DNA mutations in the IL7R gene responsible for severe combined immunodeficiency with absent T cells but preserved B and NK cells. Variants disrupt interleukin‑7 signalling, blocking T‑cell development. The report classifies pathogenic, likely pathogenic, and uncertain variants according to ACMG guidelines, enabling precise diagnosis and early intervention.
يكشف هذا الاختبار الطفرات الجينية في جين IL7R المسببة لنقص المناعة المشترك الشديد مع غياب الخلايا التائية مع بقاء الخلايا البائية والقاتلة الطبيعية.
2. How is the sample collected and what preparation is required?
Home collection by a DHA‑licensed phlebotomist using cold‑chain logistics requires only a small blood volume or a drop on an FTA card. No fasting is necessary. A genetic counselling session to draw a detailed pedigree is mandatory before the test to maximise interpretive accuracy. The nurse will verify your clinical history and identity, and samples are shipped to our ISO‑certified facility immediately.
يتم جمع العينة منزلياً عبر ممرض مرخص من هيئة الصحة بدبي، مع استشارة وراثية إلزامية لرسم شجرة العائلة قبل التحليل.
3. Who should consider this test?
Newborns with abnormal TREC assay, infants with recurrent infections, or families with a history of unexplained early death should test urgently. Adults with idiopathic lymphopenia or suspected delayed‑onset combined immunodeficiency also benefit. The is approved for minors under strict CDS Law 2026 guidelines with parental consent and genetic counselling.
المواليد الذين تظهر لديهم نتائج غير طبيعية في فحص TREC، والرُّضع المصابون بعدوى متكررة، وأفراد العائلات التي لديها تاريخ من الوفيات المبكرة غير المبررة.
UAE Regulatory Compliance & Accreditations
This service strictly adheres to Federal Decree‑Law No. 41 of 2024 (Article 87) on medical genetic testing, the CDS Law 2026 for minors, and the UAE Personal Data Protection Law (PDPL). All patient data is encrypted and stored within UAE sovereign data centres.
Facility License: 9834453 | ISO 9001:2015 Certification: INT/EGQ/2509DA/3139
Home Collection Hours: 8 AM – 11 PM daily. WhatsApp Support: +971 54 548 8731
Medical Director: Dr. Prabhakar Reddy, DHA License 61713011 | © 2026 DNA Labs UAE
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians