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Test Price

2,800 AED

โœ… Home Collection Available

IKBKB Gene Immunodeficiency Type 15 Genetic Test in UAE | AED 2,800 | DHA Licensed

Executive Summary & Core Metrics

Executive Summary โ€“ Clinical Precision & UAE Patient Trust

  • โœ“ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-Accredited NGS Processing, validated against international reference datasets.
  • โœ“ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available Daily from 8 AM to 11 PM.
  • โœ“ Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by a DHA-licensed specialist.
  • โœ“ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The IKBKB Gene Immunodeficiency Type 15 Genetic Test identifies pathogenic mutations in the IKBKB gene using Next-Generation Sequencing (NGS), enabling definitive diagnosis and personalised care for combined immunodeficiency. This molecular analysis provides single-nucleotide resolution across the entire coding region, detecting pathogenic variants and variants of uncertain significance (VUS).

Feature Our Test
IKBKB Genetic Test
Closest Alternative
Precision Single-nucleotide resolution; pathogenic & VUS detection across entire IKBKB coding region Immunophenotyping & clinical criteria alone โ€“ high false-negative rate for atypical presentations
Method Next-Generation Sequencing (NGS) with full bioinformatic curation (ISO 9001:2015) Flow cytometry, immunoglobulin levels, lymphocyte proliferation assays
Speed / TAT 21โ€“28 Business Days for comprehensive report 1โ€“2 weeks for preliminary immune workup; no genetic confirmation

Physician Insight & Safety Protocols

"A suspected primary immunodeficiency can be an uncertain and worrying time for any family. This targeted NGS analysis provides a definitive molecular diagnosis, enabling precise treatment planning, surveillance for complications, and accurate genetic counselling for relatives. Results must always be interpreted alongside the full clinical history and immunological workup."

โ€” Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Medication Advisory

Important Notice

Do not discontinue any prescribed medication or immunotherapy without consulting your treating physician. Genetic test results must not be used to self-adjust treatment. Always discuss findings with your specialist before making any changes to your care plan.

Exclusion Criteria & Emergency Red Flags

  • Exclusion: Inability to provide informed consent (patient or legal guardian); absolute contraindication to venipuncture (severe coagulopathy without correction).
  • Exclusion: For home collection, patient must be haemodynamically stable and not acutely unwell.
  • ER Red Flag: If you experience high fever, uncontrolled infection, severe respiratory distress, or signs of sepsis, seek immediate emergency careโ€”do not delay for genetic testing.
  • Red Flag: The test cannot replace urgent immunological evaluation in acutely decompensating patients.

Patient FAQ & Clinical Guidance

1. What does the IKBKB NGS test diagnose?

This test identifies mutations in the IKBKB gene that cause autosomal recessive immunodeficiency type 15, a combined immune defect leading to recurrent infections, severe eczema, and autoimmunity. The result confirms or rules out this specific genetic form of primary immunodeficiency.

2. How is the DNA sample collected, and is a hospital visit necessary?

A simple blood draw or a single drop of blood on an FTA card is all that is required. Our VIP Mobile Phlebotomy service brings a trained nurse to your home between 8 AM and 11 PM daily, with temperature-controlled cold-chain transport to the laboratory.

3. How will I receive my results, and what do they mean clinically?

Your comprehensive report will classify the variant as pathogenic, likely pathogenic, or a variant of uncertain significance, accompanied by a telephonic consultation with a genetics specialist to explain the impact on your diagnosis and family risk. The full report is typically available within 21โ€“28 business days.

4. Can this test be used for family screening or prenatal diagnosis?

Yes, once a pathogenic IKBKB variant is identified in a proband, targeted testing can be offered to at-risk family members and can inform reproductive planning. A separate genetic counselling session is required before any prenatal testing.

UAE Regulatory & Data Privacy Adherence

Compliance Framework

  • Data Protection: All genetic data is handled in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), ensuring strict confidentiality and consent-based processing.
  • Health Information Governance: Compliant with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, safeguarding electronic health records and digital clinical data.
  • Clinical Safety & Consent: Patient safety and informed consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability, guaranteeing legal and ethical standards for all diagnostic procedures.
  • Laboratory Accreditation: The testing laboratory operates under ISO 9001:2015 certified processes and is fully licensed by the Dubai Health Authority (DHA).

Clinical & Logistical Metadata

Test Name IKBKB Gene Immunodeficiency Type 15 Genetic Test
Price (AED) AED 2,800
Turnaround Time 21โ€“28 Business Days
Sample Type / Matrix Peripheral Whole Blood (Venipuncture or FTA Card)
Methodology Used Next-Generation Sequencing (NGS) โ€“ Targeted Gene Panel
ICD-10-CM Code D81.89
LOINC Code 31208-2
DHA Facility License & Laboratory Address License No. 1143 โ€” Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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โœ… DHA Certified โœ… ISO 15189 โœ… HIPAA Compliant

Available in Arabic, English, Hindi & Urdu

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ISMS 27001:2022

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ISO Accredited

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HIPAA

All reports reviewed by DHA-Certified physicians