Test Price
8,500 AED✅ Home Collection Available
HLA Single Antigen Bead Assay (DSA‑SAB) for Class I & II IgG Antibodies in UAE | 8500 AED | 2026 DHA Guidelines
تحليل مقايسة الخرزة وحيدة المستضد HLA للغلوبولين المناعي G من النوعين الأول والثاني (DSA-SAB) في الإمارات | 8500 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: يضمن فحص HLA DSA-SAB حساسية تشخيصية بنسبة 99.9%، وجمع عينات منزلي بمستوى مستشفى، وإرشادات سريرية هاتفية بعد الفحص، وخدمة تحقق من التغطية التأمينية عبر واتساب +971 54 548 8731.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by licensed professionals.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 (DHA Facility License: 9834453).
Clinical Overview & Test Comparisons
The HLA Single Antigen Bead Assay (DSA‑SAB) is the gold‑standard Luminex‑based test for detecting donor‑specific anti‑HLA Class I and II IgG antibodies to assess humoral alloreactivity pre‑ and post‑transplant. This highly sensitive assay quantifies mean fluorescence intensity (MFI) to guide immunosuppression and monitor antibody‑mediated rejection in kidney transplant recipients. يُعتبر تحليل DSA-SAB المعيار الذهبي لتقييم المناعة الخلطية قبل وبعد زراعة الأعضاء.
| Feature | Our Test (DSA‑SAB Luminex) | Closest Alternative (CDC Crossmatch / ELISA) |
|---|---|---|
| Methodology | Luminex X‑Map technology – fully quantitative | Complement‑dependent cytotoxicity (CDC) or semi‑quantitative ELISA |
| Specificity for DSA | High – identifies individual antigen specificities | Low to moderate; may miss low‑titre non‑cytotoxic antibodies |
| Clinical Sensitivity | >95% for detecting relevant DSA | 70–80% |
| Turnaround Time | 10–12 working days | 1–2 days (CDC) / 3–5 days (ELISA) |
Physician Insight & Safety Protocol
“As a consultant nephrologist, I emphasize that a positive DSA‑SAB result requires careful clinical correlation with graft function, biopsy findings (Banff criteria), and overall immunosuppression regimen. I understand waiting for these results can be stressful, but our team ensures your sample is handled with the highest care and you receive compassionate, expert post‑test guidance.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
🛑 Medication Warning: Do not discontinue prescribed immunosuppressive medication without consulting your doctor. Abrupt changes can trigger severe rejection episodes.
Exclusion Criteria & ER Red Flags
- Test may be postponed if: active systemic infection, recent vaccination (within 4 weeks), or recent IVIG/rituximab therapy that could interfere with bead assay.
- Emergency Red Flags – Seek immediate care if you experience: sudden drop in urine output, graft tenderness, fever, severe hypertension, or acute shortness of breath. These may indicate acute rejection or infection.
Frequently Asked Questions (FAQ) & Clinical Guidance
1. What does the HLA Single Antigen Bead Assay detect?
This test detects and measures donor‑specific anti‑HLA Class I and II IgG antibodies to predict antibody‑mediated transplant rejection. It is used pre‑transplant to assess sensitization and post‑transplant to monitor the emergence of de novo DSA, enabling timely intervention.
يكشف هذا التحليل عن الأجسام المضادة IgG الموجهة ضد مستضدات HLA الخاصة بالمتبرع ويقيسها لتقييم خطر الرفض بوساطة الأجسام المضادة ويتيح التدخل المبكر.
2. How should I prepare for the HLA DSA-SAB blood test?
Provide a brief clinical history; no fasting is required and you may continue prescribed immunosuppression unless your physician advises otherwise. The requires only 2 mL of serum, collected from one SST tube, shipped refrigerated. You will be asked to share your transplant date, donor specifics, and recent medication changes.
قدّم تاريخًا سريريًا موجزًا، ولا يشترط الصيام ويمكنك مواصلة الأدوية المثبطة للمناعة ما لم يوصِ الطبيب بخلاف ذلك. تُسحب العينة (2 مل مصل) في أنبوب فصل وتُرسل مبردة.
3. When will I receive my results and what do they mean?
Results are available within 10–12 working days; a positive DSA indicates increased risk of antibody‑mediated rejection. MFI values are reported with interpretive guidelines. Your transplant team will correlate the findings with clinical and biopsy data to decide on therapy adjustments. A negative result generally implies lower immunological risk.
تظهر النتائج خلال 10–12 يوم عمل، ويشير وجود DSA إلى ارتفاع خطر الرفض المناعي بوساطة الأجسام المضادة. تُفسر القيم بالتعاون مع الفريق الطبي المعالج.
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