Test Price
1,200 AED✅ Home Collection Available
HLA Panel Reactive IgG Antibodies (PRA) Screen in UAE | 1200 AED | 2026 DHA Guidelines
تحليل الأجسام المضادة البانلتة المناعية IgG لمستضدات الكريات البيضاء (اختبار PRA) في الإمارات | 1200 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: يقدم تحليل PRA فحصًا دقيقًا لقياس نسبة الأجسام المضادة المتفاعلة مع مستضدات الكريات البيضاء لتقييم مخاطر رفض زراعة الأعضاء، بدقة تشخيصية تبلغ 99.9% عبر مختبر معتمد من هيئة الصحة بدبي. الامتثال الكامل للقانون الاتحادي رقم 41 لسنة 2024 (المادة 87)، وقانون حماية القصر CDS 2026، وقانون حماية البيانات الشخصية PDPL الإماراتي.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing (ISO 9001:2015, Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by our specialist medical team.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Comprehensive Pre-Transplant Immunological Assessment
The HLA Panel Reactive IgG Antibody (PRA) Screen quantifies the percentage of pre-formed IgG antibodies against a panel of human leukocyte antigens, providing a critical risk stratification tool for solid organ and hematopoietic stem cell transplantation. Our ISO-certified Luminex X-MAP bead-based assay delivers superior sensitivity and specificity compared to conventional complement-dependent cytotoxicity methods, enabling precise donor-recipient immunological matching.
| Feature | Our HLA PRA IgG Screen (Luminex X-MAP) | Standard Complement-Dependent Cytotoxicity (CDC) |
|---|---|---|
| Methodology | Luminex X-MAP bead-based multiplex flow cytometry | Complement-dependent cytotoxicity assay |
| Antibody Detection | All IgG HLA antibodies, including non-complement-fixing | Only complement-fixing antibodies (misses non-complement-activating) |
| Sensitivity | >99% for clinically relevant HLA antibodies | ~80% (low sensitivity for non‑cytotoxic antibodies) |
| Specificity | High specificity with single antigen bead discrimination | Lower specificity, can show cross-reactive results |
| Turnaround Time | 10–12 days | 5–7 days (less informative) |
| Clinical Interpretation | Quantitative %PRA and antibody specificity for precise donor allocation | Qualitative positive/negative; often requires follow-up testing |
Physician Insight & Safety Protocol
As a clinician, I understand that awaiting transplant workup can be emotionally challenging. This test provides vital immunological data, but results must be interpreted within the full clinical context, including your medical history and physical examination. Please remember that a positive PRA screen indicates sensitization but does not alone determine transplant outcome; your multidisciplinary team will guide you through the next steps.
— Dr. PRABHAKAR REDDY (DHA Licence: 61713011), Consultant Transplant Immunologist
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Not suitable if you have received IV immunoglobulin (IVIG) or rituximab within the last 3 months (can interfere with antibody detection).
- Avoid testing during active systemic infection or if you have an untreated bleeding disorder; consult your physician first.
- Seek immediate medical attention (Emergency Room) if you experience any of the following signs of acute transplant rejection:
- Sudden pain, tenderness, or swelling over the transplant site
- Fever >38°C with no clear infection source
- Significant decrease in urine output (kidney transplant) or new jaundice (liver transplant)
- Unexplained shortness of breath or cough (lung transplant)
Patient FAQ & Clinical Guidance
Q1: What does a positive PRA screen mean for my transplant eligibility?
A: A positive PRA screen indicates the presence of IgG HLA antibodies, potentially increasing transplant rejection. The specific antibody profile and calculated panel reactive antibody percentage help your transplant team identify compatible donors or desensitization protocols. Our telephonic clinical guidance can explain your personal risk.
س1: ماذا تعني نتيجة PRA الإيجابية لعملية الزراعة؟
نتيجة PRA الإيجابية تشير إلى وجود أجسام مضادة ضد HLA، ما يزيد احتمال رفض العضو. يحدد فريق زراعة الأعضاء المتبرعين المتوافقين أو بروتوكولات إزالة التحسس بناءً على نوع الأجسام المضادة المحددة.
Q2: How should I prepare for the PRA blood test?
A: For accurate results, draw blood 48 hours after dialysis and provide your full medical history. Avoid sample collection immediately after blood transfusion or IVIG therapy; our phlebotomist will verify eligibility at the time of home collection.
س2: كيف أستعد لفحص الدم PRA؟
لنتائج دقيقة، اسحب عينة الدم بعد 48 ساعة من غسيل الكلى وقدّم تاريخك الطبي الكامل. يجب تجنب سحب العينة بعد نقل الدم أو علاج بالغلوبيولين المناعي الوريدي مباشرة.
Q3: How quickly will I receive my PRA results, and what do they show?
A: Your Luminex PRA report delivers within 10-12 days, showing percent panel reactivity and antibody identification. The report includes a detailed list of donor-specific anti-HLA antibodies, allowing precise immunological risk assessment. You will receive a notification via WhatsApp when the report is ready, with the option of a post- clinical discussion.
س3: متى سأحصل على نتائج PRA وماذا تظهر؟
تقرير فحص PRA يصلك خلال 10-12 يومًا، موضحًا نسبة التفاعل البانلي وتفاصيل الأجسام المضادة المحددة. يتضمن التقرير قائمة بالأجسام المضادة الخاصة بالمتبرع لتقييم المخاطر المناعية بدقة.
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