Also known as: HLA-B*57:01 Genotyping, Abacavir Hypersensitivity Screening
Test Price
1,200 AEDโ Home Collection Available
๐ Results in 10โ12 business days from sample receipt
HLA Hypersensitivity to Abacavir (B*57:01) Test in UAE | 1200 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AMโ11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance by DHA-licensed physicians.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The HLA-B*57:01 test is a mandatory pharmacogenetic screen that identifies genetic susceptibility to abacavir hypersensitivity โ a potentially fatal reaction affecting 5โ8% of HIV patients. Per current DHA clinical guidelines, this test must be performed prior to initiating any abacavir-containing antiretroviral regimen.
Comparative Test Accuracy
| Feature | Our Test (DNA Labs UAE) | Closest Alternative |
|---|---|---|
| Precision | 99.9% Sensitivity/Specificity (PCR + Sanger Sequencing) | Standard PCR only (risk of false negatives) |
| Methodology | PCR with sequence-based typing (SBT) & double-read confirmation | SSPโPCR without confirmatory sequencing |
| Speed | Rapid 10โ12 days from sample receipt | 14โ21 days typical |
Physician Insight & Safety Protocols
โA positive HLA-B*57:01 result is a strong predictor of abacavir hypersensitivity; however, clinical correlation with patient history and symptoms is essential. Never rely solely on genetic testing. Always integrate with a comprehensive evaluation by a qualified HIV specialist.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed medication without consulting your doctor. Abacavir dosing adjustments must be managed by a specialist. If you develop rash, fever, dyspnea, or hypotension after starting abacavir, seek immediate medical attention โ this may indicate a hypersensitivity reaction.
Exclusion Criteria & Emergency Red Flags
- Active severe systemic infection that may compromise specimen integrity.
- Inadequate sample (hemolyzed, clotted, or insufficient volume) requires recollection.
- Emergency: immediate medical attention for symptoms of hypersensitivity.
Patient FAQ & Clinical Guidance
1. Why must I take this test before starting abacavir?
A genetic screen for HLA-B*57:01 prevents life-threatening hypersensitivity reactions, which occur in 5โ8% of patients without testing. UAE guidelines mandate this to ensure antiretroviral safety.
2. Is home collection available throughout the UAE?
Yes, our VIP Mobile Phlebotomy service covers Dubai, Abu Dhabi, Sharjah, and all Emirates, operating 8 AM to 11 PM daily. Contact WhatsApp to schedule.
3. How is the sample collected and what is the turnaround time?
A blood sample (4 mL) or buccal swab is collected by our mobile nursing team in your home, shipped under cold chain. Results are available within 10โ12 days from sample receipt.
UAE Regulatory & Data Privacy Adherence
Compliance: This service strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Laboratory processing is performed under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) accredited facilities. Parental consent is required for individuals under 18.
Clinical & Logistical Metadata
| Test Name | HLA-B*57:01 (Abacavir Hypersensitivity) Genotyping |
| Price (AED) | 1,200 |
| Turnaround Time | 10โ12 business days from sample receipt |
| Sample Type / Matrix | Whole blood (EDTA) or buccal swab |
| Methodology Used | PCR with Sequence-Based Typing (SBT) and confirmatory sequencing |
| ICD-10-CM Code | Z01.818 (Encounter for other specified special examinations) |
| LOINC Code | 52091-3 (HLA-B*57:01 gene [Presence] in Blood or Tissue by Molecular genetics) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
Preparation Required
["No fasting required", "No specific medication or diet restrictions"]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians