Test Price
2,800 AED✅ Home Collection Available
COL4A6 Gene Deafness, X-Linked Type 6 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين COL4A6 للصمم المرتبط بالكروموسوم X من النوع السادس في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM - 11 PM).
Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance for result interpretation by DHA-licensed genetic experts.
Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Executive Summary
ملخص تنفيذي: اختبار جيني متقدم بتقنية التسلسل من الجيل التالي (NGS) لتحليل جين COL4A6 للكشف عن الطفرات المسببة للصمم المرتبط بالكروموسوم X من النوع السادس. يُجرى وفقًا لإرشادات هيئة الصحة بدبي لعام 2026، ويوفر تشخيصًا دقيقًا مع استشارة وراثية متكاملة، مع الالتزام الكامل بالمرسوم بقانون اتحادي رقم 41 لعام 2024 وقانون خصوصية البيانات الصحية.
CPT Code: 81407
LOINC: LA26332-9 (Genetic analysis for deafness)
Clinical Overview
This test utilizes Next Generation Sequencing (NGS) to analyze the coding regions and splice sites of the COL4A6 gene, identifying pathogenic variants responsible for X-linked deafness type 6. This form of non-syndromic hearing loss predominantly affects males, and carrier detection in females is critical for informed reproductive planning and early intervention.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative |
|---|---|---|
| Precision | Full gene NGS with copy number variation (CNV) analysis via robust bioinformatic pipelines. | May not include CNV analysis; limited to point mutations. |
| Methodology | NGS with Long-Range PCR for coverage of GC-rich and homologous regions. | Standard short-read NGS, potential for allelic dropout. |
| Speed | 3 to 4 Weeks (Facility License: 9834453). | 4 to 6 Weeks. |
Physician Insight & Safety Protocol
"As a clinician, I understand that pursuing a genetic diagnosis for hearing loss can be a profound step for a family. This test is a powerful tool, but it is one piece of the puzzle; results must be meticulously correlated with audiometric evaluation and family history. My commitment is to ensure every patient receives compassionate guidance, so you never navigate this path alone."
— Dr. PRABHAKAR REDDY, DHA License: 61713011
Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & ER Red Flags
- Absolute Exclusion: Inability to provide a valid DHA/MOHAP-authorized request form from an ENT Doctor, Clinical Geneticist, or relevant specialist. Self-referral for minors without parental consent violates UAE CDS Law 2026.
- Exclusion: Recent (less than 4 weeks) allogeneic blood transfusion or bone marrow transplant, as the sample would reflect donor DNA.
- Emergency Red Flag: This test is for diagnostic and prognostic purposes, not for acute management. If a patient presents with sudden sensorineural hearing loss (SSNHL), this is a medical emergency. Proceed immediately to the nearest emergency department.
Patient FAQ & Clinical Guidance
What is the diagnostic yield of the COL4A6 gene test for X-linked deafness?
This next-generation sequencing assay provides a definitive molecular diagnosis by identifying pathogenic variants in the COL4A6 gene, which, when coupled with clinical audiometry, offers exceptionally high analytical sensitivity and specificity. A positive result confirms the genetic etiology of non-syndromic X-linked hearing loss, allowing for targeted clinical management and accurate genetic counseling for at-risk family members.
هل يكتشف هذا الاختبار جميع أسباب الصمم الوراثي؟
لا، هذا الاختبار مصمم خصيصًا لتحليل جين COL4A6 المرتبط بالصمم المرتبط بالكروموسوم X من النوع السادس فقط. إذا كانت نتيجة الاختبار سلبية، فقد يوصي طبيبك بإجراء اختبار لوحة جينية أوسع للصمم لتقييم الجينات الأخرى.
What are the pre- requirements and is genetic counseling included?
A comprehensive genetic counseling session is mandatory to draw a detailed pedigree chart of family members affected with COL4A6-related deafness and to document a complete clinical history. You must not discontinue any medication without consultation, and a blood sample, extracted DNA, or one drop of blood on an FTA card can be collected via our ISO-certified home collection service between 8 AM and 11 PM.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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