Test Price
2,800 AED✅ Home Collection Available
MSH2 Gene Mismatch Repair Cancer Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين MSH2 لمتلازمة السرطان المرتبطة بإصلاح عدم التطابق في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: فحص جيني دقيق عالي الحساسية بنسبة 99.9% لجين MSH2 للكشف عن متلازمة لينش، مع سحب عينات منزلي معتمد وخدمة استشارية بعد النتيجة.
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 Certified NGS processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital‑grade home collection (8 AM – 11 PM) with ISO‑certified cold‑chain transport. VIP mobile phlebotomy included.
- Clinical Guidance: Telephonic post‑test clinical guidance by a DHA‑licensed genetic counsellor to interpret your results.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Comprehensive NGS Analysis for Lynch Syndrome
The MSH2 gene mismatch repair cancer syndrome NGS test detects germline mutations in the MSH2 gene, a critical marker for Lynch syndrome (hereditary non‑polyposis colorectal cancer). This NGS‑powered analysis enables personalised cancer surveillance, risk‑reduction strategies, and informed family planning.
| Parameter | Our NGS Test (ISO‑Certified) | Standard Single‑Gene Sanger Sequencing |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) – full coding region ± deletion/duplication analysis | Sanger sequencing – point mutations only |
| Diagnostic Precision | >99.9% analytical sensitivity; detects SNVs, indels, and CNVs | ~95% sensitivity; may miss large rearrangements |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Clinical Utility | Gold‑standard Lynch syndrome diagnosis, cascade testing, and genotype‑driven surveillance | Limited; often requires reflex to MLPA for comprehensive review |
Physician Insight & Safety Protocol
“As a specialist in genomic medicine, I understand the emotional weight of hereditary cancer risk. This NGS test provides actionable clarity, but results must be interpreted in the context of your personal and family history. I strongly encourage you to consult your oncologist or genetic counsellor before making any health decisions.”
— Dr. PRABHAKAR REDDY, DHA‑Licensed Specialist (DHA: 61713011)
⚠ Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Allogeneic bone marrow transplant within the last 6 weeks (donor DNA interference invalidates germline analysis).
- Inability to provide informed consent or complete a pre‑test genetic counselling session (mandatory per UAE CDS Law 2026 for minors).
- Red Flags – Seek immediate medical attention: Unexplained rectal bleeding, sudden change in bowel habits, unintended weight loss, or acute abdominal pain.
Pre‑test Requirement: A detailed clinical history and a genetic counselling session, including a pedigree chart of family members affected by Lynch‑spectrum cancers, are required before sample collection. Our team will guide you through this process.
Frequently Asked Questions
1. Who should consider the MSH2 gene mismatch repair cancer syndrome NGS test?
Individuals with a personal or family history of colorectal, endometrial, or other Lynch‑associated cancers, particularly those diagnosed under age 50, should consider MSH2 genetic testing to define hereditary risk and guide life‑saving precision surveillance. The test is also invaluable for asymptomatic family members undergoing cascade screening after a known mutation is identified.
2. كيف يتم إجراء فحص جين MSH2 وما هي مدة ظهور النتائج؟
يتم إجراء الفحص عبر سحب عينة دم بسيطة أو بقعة دم على بطاقة FTA، ثم يُحلل الحمض النووي باستخدام تقنية التسلسل الجيني المتقدم (NGS)، وتظهر النتائج خلال 3 إلى 4 أسابيع مع تقرير طبي مفصل يشمل توصيات المتابعة والمراقبة.
3. Can the NGS test detect all possible MSH2 mutations?
Our NGS test covers the entire coding region of the MSH2 gene, including point mutations, small insertions/deletions, and copy number variations, achieving >99.9% analytical sensitivity. Rare deep intronic or promoter mutations may require additional specialised analysis, which we can coordinate if clinical suspicion remains high.
Book Your NGS Today – Home Collection Available
WhatsApp: +971 54 548 8731 | ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139)
Compliant with Federal Decree‑Law No. 41 of 2024 (Art. 87), UAE CDS Law 2026 (Minors), and UAE PDPL. All data handled with strict confidentiality.
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