Test Price
1,600 AED✅ Home Collection Available
Hemochromatosis Common Mutation Analysis in HFE Gene (H63D, S61C & C282Y) in UAE | 1600 AED | DHA Guidelines
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited Sanger sequencing processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Complimentary telephonic post-test clinical guidance for result interpretation by our expert team.
Insurance: Direct billing verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
This test employs Sanger sequencing to precisely detect three common HFE gene mutations (H63D, S61C, C282Y) causing hereditary hemochromatosis—a silent iron overload disorder. Unlike non-genetic iron tests, it provides definitive molecular confirmation and guides family screening.
| Feature | Our HFE Gene Test | Closest Alternative: Iron Studies |
|---|---|---|
| Method | Sanger Sequencing (Gold Standard) | Biochemical Assays (Ferritin, TSAT) |
| Diagnostic Precision | 99.9% sensitivity for common mutations | Indirect; may miss early-stage iron loading |
| Turnaround Time | 7–10 days | Same day (but less informative) |
| Clinical Utility | Confirms hereditary hemochromatosis; guides family screening | Initial suspicion; requires genetic test for confirmation |
| DHA Compliance | Full DHA/MOHAP standards | Standard laboratory compliance |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I emphasize that a positive HFE mutation result must be correlated with iron studies and family history; it does not automatically mean clinical disease. Your treatment should always be guided by a specialist.”
— Lina Osama Zaki Quteineh, DHA No. 9294403
🚨 Critical Advisory
- Do not discontinue prescribed medications or defer phlebotomy based solely on this test result.
- If you experience new severe fatigue, joint pain, abdominal pain, or bronze skin discoloration, seek immediate medical care at the nearest emergency department.
- This test is contraindicated in patients who have received a recent blood transfusion (within 4 weeks) or are pregnant without medical necessity; always consult your doctor.
🚫 Exclusion Criteria
- Active hemolysis, acute hepatic injury, or known confounding genetic disorder that may affect result interpretation.
Patient FAQ & Clinical Guidance
1. How accurate is this HFE gene test, and can it miss some mutations?
This Sanger sequencing test achieves over 99.9% sensitivity for the three most common mutations; however, rare HFE variants beyond these are not covered by this targeted analysis.
2. Do I need a doctor’s prescription for this in the UAE?
A physician’s prescription is required for all HFE genetic testing; however, it is not mandatory for pregnancy or pre-travel health check-ups when asymptomatic.
3. How is the sample collected, and will my insurance cover the cost?
A simple peripheral blood sample is collected at your home by our DHA-licensed phlebotomist; most UAE insurers cover genetic testing for hereditary hemochromatosis, and we verify your coverage instantly via WhatsApp.
UAE Regulatory & Data Privacy Adherence
Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields govern the handling of your genetic data. DNA Labs UAE maintains full compliance with these regulations, safeguarding your privacy and health information. DHA Facility License No. 1143 ensures rigorous oversight.
Clinical & Logistical Metadata
| Test Name | Hemochromatosis Common Mutation Analysis in HFE Gene (H63D, S61C & C282Y) |
| Price (AED) | 1,600 |
| Turnaround Time | 7–10 business days |
| Sample Type / Matrix | Peripheral Whole Blood |
| Methodology Used | Sanger Sequencing |
| ICD-10-CM Code | E83.1 |
| LOINC Code | 23877-0 |
| DHA Facility License & Lab Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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