Test Price
2,800 AED✅ Home Collection Available
TRIOBP Gene Deafness (Autosomal Recessive Type 28) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- ✅ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-IEC 15189:2022 accredited processing, covering all coding regions and splice sites of the TRIOBP gene.
- 🚑 Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM to 11 PM).
- 🩺 Clinical Guidance: Complimentary telephonic post-test genetic counselling session (English or Arabic).
- 📑 Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 – accepted under UAE DHA/DOH mandates.
Test Overview & Methodology
This Next‑Generation Sequencing (NGS) test comprehensively screens the TRIOBP gene for pathogenic variants linked to autosomal recessive deafness type 28 (DFNB28), offering a definitive molecular diagnosis for hereditary hearing loss. The test identifies point mutations, small insertions/deletions, and copy‑number variations across all exons with 99.9% analytical sensitivity, confirmed by Sanger sequencing.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision (Diagnostic Sensitivity) | 99.9% – full‑gene NGS with CNV detection | ~85% – targeted common variant panels |
| Methodology | Illumina NGS + Sanger confirmation | Multiplex Ligation‑dependent Probe Amplification (MLPA) or single‑gene sequencing |
| Turnaround Time | 3 – 4 weeks (includes bioinformatics & clinical report) | 6 – 8 weeks (extended by reflex testing) |
| Sample Requirement | 1‑2 mL whole blood / DNA / FTA card (non‑invasive paediatric option) | Often 3‑5 mL blood with cold‑chain restrictions |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I remind each family that genetic results – whether positive or negative – must always be correlated with comprehensive clinical evaluation, including audiologic assessment and detailed family history. This test provides essential molecular data but is not a standalone diagnosis.” — Dr. Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
⚠️ Do not discontinue any prescribed medication (e.g., steroids, hearing aids, or implants) without consulting your treating physician. This genetic test does not replace urgent audiologic care.
Safety Exclusion Criteria
- Sudden‑onset unilateral or bilateral hearing loss within 72 hours – seek emergency ENT evaluation immediately.
- Presence of acute otalgia, otorrhoea, or acute vestibular crisis (vertigo with nausea/vomiting) – home collection is contraindicated; visit a hospital directly.
- Not suitable for minors without legal guardian consent as per UAE child protection laws. Minors require an accompanying parent/guardian during sample collection.
- If the patient is on anticoagulants, inform the phlebotomist; consider FTA card as an alternative sample type.
- Pre‑test genetic counselling session (including pedigree chart) is mandatory before sample collection.
Patient FAQ & Clinical Guidance
1. What exactly does the TRIOBP gene test detect, and how accurate is it?
This NGS test identifies point mutations, small insertions/deletions, and copy‑number variations across all coding regions of the TRIOBP gene with 99.9% analytical sensitivity. All reported pathogenic variants are confirmed by Sanger sequencing, ensuring result reliability above 99.99%. It is designed to diagnose autosomal recessive deafness type 28 (DFNB28) in symptomatic individuals and clarify carrier status in family members.
2. How should I prepare, and can my child give a sample?
No fasting or medication abstinence is required. Simply provide a 1‑2 mL blood sample or a painless one‑drop FTA card for paediatric patients. For children under 12 years, the FTA card method avoids venipuncture. Pre‑test genetic counselling (tele‑counselling available) is mandatory to document family history. Home collection by a paediatric phlebotomist can be arranged via WhatsApp.
3. What happens after I receive the report, and are follow‑up services available?
Every report includes a plain‑language clinical summary. You are entitled to a 20‑minute tele‑consultation with a DHA‑licensed genetic counsellor to interpret results. If a pathogenic variant is found, we provide referral pathways to paediatric audiology, cochlear implant centres, and clinical geneticists. Negative reports may still warrant advanced testing if hearing loss is progressive – your ENT specialist will guide next steps. All data handling complies with UAE PDPL; your genetic information is never shared without explicit consent.
UAE Regulatory & Data Privacy Adherence
This laboratory and its procedures strictly adhere to the Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. All genetic data is encrypted, access‑controlled, and never shared without written patient consent. Regular audits ensure compliance with UAE DHA and DOH standards.
Clinical & Logistical Metadata
| Test Name | TRIOBP Gene Deafness (Autosomal Recessive Type 28) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), DNA, or FTA card (paediatric) |
| Methodology Used | Next‑Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | H90.5, Z82.2 |
| LOINC Code | 93480-3 |
| DHA Facility License & Laboratory Address Invariants | DHA Facility License: 1143 | DNA Labs UAE – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians