Test Price
2,800 AED✅ Home Collection Available
MAP1A Gene Hearing Loss Genetic Test in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – Available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced Next-Generation Sequencing (NGS) test analyses the entire coding region of the MAP1A gene to detect pathogenic variants linked to hereditary hearing loss. The test employs targeted NGS with >200× depth, full gene coverage, achieving 99.9% analytical sensitivity and specificity for single-nucleotide variants, small insertions/deletions, and copy-number variants. Results are interpreted within a clinical context of progressive sensorineural hearing loss and autosomal dominant inheritance (DFNA49).
Why Our Test Outperforms
| Feature | Our Test – MAP1A NGS | Closest Alternative (WES) |
|---|---|---|
| Methodology | Targeted NGS with >200× depth, full gene coverage | Whole Exome Sequencing (WES) |
| Precision | 99.9% analytical sensitivity/specificity | 95–98% for SNVs; incidental findings risk |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Clinical Focus | Hearing loss – MAP1A only; no incidental burden | Broad; may reveal unrelated conditions |
| Cost (AED) | 2800 | Typically >5000 |
Physician Insight & Safety Protocols
“Genetic testing for MAP1A provides critical diagnostic clarity for hereditary hearing loss, but interpretation must always be integrated with a complete audiological evaluation and family pedigree. A pathogenic variant confirms DFNA49; however, the absence of a variant does not exclude other genetic or environmental causes. Customised counselling and clinical follow-up are essential for every patient.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
⚠ Medication Advisory
Do not discontinue or alter any prescribed medication without consulting your treating physician. Some medications may influence symptom presentation or test interpretation.
Safety Exclusions & Emergency Red Flags
Exclusion Criteria (Do Not Proceed If):
- Inability to provide informed consent or severe cognitive impairment
- Active high‑fever infection or acute systemic illness at time of blood draw
- Recent major surgery or blood transfusion within 2 weeks
- Uncontrolled bleeding disorder
Red Flags – Urgent ER Evaluation Needed:
- Sudden, complete hearing loss in one or both ears
- Acute vertigo with nausea/vomiting and unsteadiness
- Asymmetric facial weakness or numbness
- Severe tinnitus with new neurological symptoms
Patient FAQ & Clinical Guidance
1. What is the MAP1A gene and why is it tested for hearing loss?
Snippet: The MAP1A gene provides instructions for a protein essential for inner ear hair cell stability and sound transduction; pathogenic variants cause DFNA49 autosomal dominant hearing loss.
This test sequences all coding exons of MAP1A to identify single‑nucleotide variants, small deletions/insertions, or copy‑number changes that disrupt microtubule‑associated protein function in the cochlea. Early genetic diagnosis can guide audiological rehabilitation, cochlear implant candidacy, and family risk assessment.
2. Who should consider this genetic test?
Snippet: Individuals with post‑lingual progressive sensorineural hearing loss, a positive family history of deafness, or known DFNA49 phenotype should undergo MAP1A NGS testing after genetic counselling.
Candidates include adults and children (with guardian consent) who have unexplained bilateral hearing loss, especially if suggestive of autosomal dominant inheritance. Pre‑genetic counselling with a pedigree analysis is mandatory to interpret the result accurately.
3. How is the sample collected and what preparation is needed?
Snippet: A simple blood draw (1–2 mL whole blood), a dried blood spot on FTA card, or previously extracted DNA can be used; no fasting required.
We offer painless VIP home phlebotomy by certified nurses. Sample integrity is preserved via ISO‑certified cold‑chain transport. Please sign the informed consent and provide a three‑generation pedigree before collection. The DNA FTA card option is ideal for infants or remote locations.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection
Your genetic data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical testing, patient consent, and safety protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Results are securely transmitted and stored with encryption, and no data is shared with third parties without your explicit written consent.
Clinical & Logistical Metadata
| Test Name | MAP1A Gene Sequencing (Hereditary Hearing Loss) |
| Price (AED) | 2800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Dried Blood Spot (FTA Card), or Extracted DNA |
| Methodology Used | Targeted Next-Generation Sequencing (NGS) with >200× average depth, full coding region coverage |
| ICD-10-CM Code | H90.3, H91.9 |
| LOINC Code | 100006-1 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Laboratory: DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians