GK Gene Glycerol kinase deficiency Genetic Test
At DNA Labs UAE, we offer the GK Gene Glycerol kinase deficiency Genetic Test for individuals suspected of having Glycerol kinase deficiency (GKD), a rare X-linked genetic disorder affecting glycerol metabolism.
Test Components and Price
- Components: GK Gene Glycerol kinase deficiency Genetic Test
- Price: 4400.0 AED
Sample Condition
We accept the following sample types:
- Blood
- Extracted DNA
- One drop of blood on FTA Card
Report Delivery
Reports are typically delivered within 3 to 4 weeks.
Method
We utilize Next-generation sequencing (NGS) technology for this test.
Test Type
This test falls under the category of Metabolic Disorders.
Doctor and Test Department
This test can be ordered by a General Physician and is conducted in our Genetics department.
Pre Test Information
Prior to the test, it is recommended to provide the clinical history of the patient who is going for the GK Gene Glycerol kinase deficiency NGS Genetic DNA Test. Additionally, a Genetic Counselling session is conducted to draw a pedigree chart of family members affected with Glycerol kinase deficiency.
Test Details
Glycerol kinase deficiency (GKD) is a rare X-linked genetic disorder that affects the metabolism of glycerol. It is caused by mutations in the GK gene, which encodes the enzyme glycerol kinase. Individuals with GKD have an inability to properly convert glycerol into glycerol-3-phosphate, leading to elevated levels of glycerol in the blood and urine.
Next-generation sequencing (NGS) is a powerful genetic testing method that can identify mutations in the GK gene associated with GKD. NGS allows for the simultaneous sequencing of multiple genes, exomes, or even genomes. This technology can detect various genetic variations, including point mutations, insertions, deletions, and rearrangements.
For NGS-based genetic testing, DNA is extracted from a blood or saliva sample. The extracted DNA undergoes library preparation and sequencing. The resulting sequence data is then analyzed using specialized bioinformatics tools to identify mutations in the GK gene. This information can help confirm a diagnosis of GKD and guide appropriate management and treatment strategies.
Benefits of Genetic Testing for GKD
Genetic testing for GKD provides valuable information for affected individuals and their families. It enables:
- Early diagnosis
- Genetic counseling
- Family planning
- Identification of potential disease-causing mutations in other genes, relevant for personalized treatment approaches or participation in clinical trials
At DNA Labs UAE, we are committed to providing accurate and reliable genetic testing services. Our GK Gene Glycerol kinase deficiency Genetic Test can help individuals and their healthcare providers make informed decisions regarding diagnosis, management, and treatment of GKD.
| Test Name | GK Gene Glycerol kinase deficiency Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Metabolic Disorders |
| Doctor | General Physician |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for GK Gene Glycerol kinase deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Glycerol kinase deficiency |
| Test Details | Glycerol kinase deficiency (GKD) is a rare X-linked genetic disorder that affects the metabolism of glycerol. It is caused by mutations in the GK gene, which encodes the enzyme glycerol kinase. GKD leads to an inability to properly convert glycerol into glycerol-3-phosphate, resulting in elevated levels of glycerol in the blood and urine. Next-generation sequencing (NGS) is a powerful genetic testing method that can be used to identify mutations in the GK gene associated with GKD. NGS allows for the simultaneous sequencing of multiple genes or even the entire exome or genome. This technology can detect both small and large genetic variations, including point mutations, insertions, deletions, and rearrangements. NGS-based genetic testing for GKD involves extracting DNA from a blood or saliva sample, followed by library preparation and sequencing. The resulting sequence data is then analyzed using specialized bioinformatics tools to identify mutations in the GK gene. This information can help confirm a diagnosis of GKD and guide appropriate management and treatment strategies. Genetic testing for GKD can provide valuable information for affected individuals and their families. It can help with early diagnosis, genetic counseling, and family planning. Additionally, NGS-based testing allows for the identification of potential disease-causing mutations in other genes, which may be relevant for personalized treatment approaches or participation in clinical trials. |
