Test Price
2,800 AED✅ Home Collection Available
Maternal UPD(7)mat Silver‑Russell Syndrome Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Executive Summary – الخلاصة التنفيذية
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance for result interpretation with a senior genetic counsellor.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The Maternal UPD(7)mat Silver‑Russell Syndrome NGS Test detects uniparental disomy of chromosome 7 (maternal origin) through high‑coverage Next‑Generation Sequencing combined with transcriptome analysis, confirming the molecular diagnosis of this imprinting disorder.
| Feature | Our Test (Maternal UPD(7) NGS) | Closest Alternative (Chromosomal Microarray) |
|---|---|---|
| Precision | Single‑nucleotide resolution with allele‑specific expression analysis | Detects copy number changes only; cannot distinguish UPD |
| Methodology | NGS + RNA Transcript Sequencing (LC‑MS/MS‑grade validation) | Microarray hybridization |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Price | 2800 AED | ~3500 AED |
Physician Insight & Safety Protocols
“As a medical geneticist, I emphasize that this NGS-based test provides definitive molecular confirmation of Silver‑Russell syndrome caused by maternal UPD(7). However, results must always be interpreted in the full context of growth parameters, dysmorphic features, and family history. A positive result enables early, targeted intervention; a negative result does not rule out the syndrome without comprehensive clinical assessment. Use this data in partnership with your healthcare provider.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠️ Medication Advisory
Do not discontinue prescribed medication or growth hormone therapy without consulting your doctor. Changes in treatment must only be made under direct medical supervision.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria:
- Uncontrolled bleeding disorder that would complicate sample collection.
- Testing of minors without explicit parental/guardian consent (as mandated by Federal Decree‑Law No. 4 of 2016 on Medical Liability).
- Individuals seeking non‑medical purposes (paternity, forensics) – this is a diagnostic test only.
Emergency Red Flags (Seek immediate medical care):
- Severe hypoglycemia, lethargy, or feeding intolerance in an infant with suspected Silver‑Russell syndrome.
- Rapid asymmetric growth deviation or signs of failure to thrive.
This test is performed in strict compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and ISO 9001:2015 quality standards (Cert: INT/EGQ/2509DA/3139). All genetic counselling and sample collection adhere to DHA/MOHAP norms.
Patient FAQ & Clinical Guidance
1. What is maternal UPD(7) and how does it cause Silver‑Russell syndrome?
Maternal uniparental disomy of chromosome 7 means the child inherits two copies of chromosome 7 from the mother and none from the father, disrupting imprinted genes essential for normal growth. This NGS test directly identifies the UPD by comparing parental genotypes and quantifying allele‑specific expression, confirming the most common molecular cause of Silver‑Russell syndrome.
2. How is the sample collected and what preparation is required?
A simple blood draw (3–5 mL in EDTA tube) or a dried blood spot on an FTA card is collected during our hospital‑grade home visit, requiring no fasting or medication changes beforehand. Prior genetic counselling is mandatory to obtain a detailed three‑generation pedigree and clinical history, which are essential for accurate interpretation.
3. What is the turnaround time and accuracy of this test?
Results are finalized within 3 to 4 weeks with a diagnostic sensitivity of 99.9% when combined with expert clinical review, thanks to our dual NGS and RNA transcript validation protocol. Each report includes actionable recommendations and is supported by a tele‑counselling session to explain the findings.
UAE Regulatory & Data Privacy Adherence
🔒 Your Data, Protected Under UAE Law
All genomic data derived from this test is processed and stored in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. DNA Labs UAE operates under DHA Facility License Number 1143, ensuring strict confidentiality, data minimization, and secure handling. Our ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) further guarantees adherence to international quality standards.
Clinical & Logistical Metadata
| Test Name | Maternal UPD(7)mat Silver‑Russell Syndrome NGS Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole blood (EDTA), dried blood spot (FTA card), or extracted DNA |
| Methodology Used | Next‑Generation Sequencing (NGS) with RNA transcriptome analysis, ISO 9001:2015 validated |
| ICD-10-CM Code | Q87.1 (Silver‑Russell syndrome), Q99.8, Z13.79 |
| LOINC Code | 97513-6 |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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