Test Price
2,800 AED✅ Home Collection Available
PPP1R17 Gene Hypercholesterolemia Susceptibility Test (NGS) in UAE | 2800 AED | DNA Labs Dubai
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity via ISO-Accredited Lab
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM)
- Clinical Guidance: Telephonic Post-Test Result Interpretation with a Specialist
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731
Test Overview & Methodology
The PPP1R17 gene test uses clinical-grade next-generation sequencing (Illumina NovaSeq technology) to detect genetic variants associated with increased susceptibility to hypercholesterolemia and premature cardiovascular events. This analysis empowers preventive cardiology through early identification of at-risk individuals, enabling targeted lifestyle modifications and pharmacological interventions before clinical manifestations develop.
| Feature | Our PPP1R17 NGS Test | Standard Lipid Panel / FH Panel |
|---|---|---|
| Precision | Targeted gene analysis with 99.9% analytical sensitivity | Phenotypic lipid measurement; limited genetic insight |
| Method | Clinical-grade NGS (Illumina NovaSeq) with ACMG-aligned bioinformatics pipeline | Enzymatic assay; Sanger sequencing for FH often limited coverage |
| Turnaround | 3 – 4 weeks with comprehensive variant interpretation report | Lipid panel: same day; genetic test: 8+ weeks, often limited coverage |
*Comparison based on CAP-accredited laboratory standards and current ACMG guidelines.
Physician Insight & Safety Protocols
"A positive genetic finding for PPP1R17 variants indicates increased susceptibility, not a confirmed diagnosis of hypercholesterolemia. Comprehensive clinical evaluation including lipid profiling, family pedigree analysis, and cardiovascular risk assessment remains essential for appropriate management. Genetic results must always be interpreted within the full clinical context."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Continuation
Do not discontinue prescribed lipid-lowering therapy or any other medication without consulting your treating physician. Abrupt cessation may lead to adverse cardiac events.
Safety Exclusion Criteria & Red Flags
- Exclusion: Acute febrile illness, recent blood transfusion (within 3 months), inability to provide informed consent, or known allergy to antiseptic used in phlebotomy.
- ER Red Flags: If you develop sudden chest tightness, shortness of breath, or one-sided weakness/speech difficulty after learning your genetic risk, call 998 or go to the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What is the PPP1R17 gene test and why is it important?
The PPP1R17 gene test uses next-generation sequencing to detect genetic variants that may increase your risk for high cholesterol and early heart disease. It empowers you and your cardiologist to implement early preventive strategies such as dietary changes, regular lipid monitoring, and, if necessary, targeted therapy before atherosclerosis develops.
2. How should I prepare for the PPP1R17 NGS test?
Preparation requires a detailed clinical history and a mandatory genetic counselling session to draw a pedigree chart of family members affected with hypercholesterolemia. For blood collection, fasting is not required; our certified phlebotomist will visit your home at your convenience through our VIP mobile phlebotomy service.
3. What does a positive result mean and what are the next steps?
A positive result indicates the presence of a variant in PPP1R17 associated with increased susceptibility, not a diagnosis of disease. You will receive a telephonic consultation with our clinical team to interpret the report, and we strongly recommend follow-up with a cardiologist for a comprehensive lipid profile and risk assessment.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Compliance Framework
This service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is processed under ISO 9001:2015 certified quality systems (Cert: INT/EGQ/2509DA/3139). Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | PPP1R17 Gene Hypercholesterolemia Susceptibility Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Clinical-grade Next-Generation Sequencing (Illumina NovaSeq) with ACMG-aligned bioinformatics pipeline |
| ICD-10-CM Code | E78.0 (Pure hypercholesterolemia), Z13.89 (Encounter for screening for genetic disease) |
| LOINC Code | 82939-0 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians