Test Price
2,800 AEDโ Home Collection Available
F5 Gene Budd-Chiari Syndrome NGS Genetic Test in UAE โ 2,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
Clinical Guidance: Telephonic Post-Test Genetic Counselling by a DHA-Licensed Consultant Medical Geneticist.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced next-generation sequencing (NGS) test screens the entire coding region of the F5 gene for pathogenic mutations linked to Budd-Chiari syndrome and inherited thrombophilia. The test provides definitive molecular diagnosis for patients with unexplained hepatic vein thrombosis.
| Feature | DNA Labs UAE NGS Test | Closest Alternative (Single-Gene PCR) |
|---|---|---|
| Precision | Full gene analysis โ detects known and novel variants | Limited to specific hotspot mutations only |
| Methodology | NGS with bioinformatics validation (โฅ800x depth) | Allele-specific PCR/gel electrophoresis |
| Turnaround Time | 3โ4 Weeks (comprehensive report) | 5โ7 Days (incomplete risk profile) |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics (DHA Registration ID: 9294403): โWhen a patient presents with Budd-Chiari syndrome, a negative traditional thrombophilia panel should not be the endpoint โ NGS of F5 can unmask rare gain-of-function mutations that drive hepatic vein thrombosis. This test is a clinical decision-support tool; its results must be correlated with liver imaging, coagulation studies, and family history to avoid both over- and under-treatment.โ
โ ๏ธ Important Advisory
Do not discontinue prescribed anticoagulation or any medication without consulting your doctor. Stopping blood thinners abruptly may trigger life-threatening clotting events.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Minors (<18 years) require mandatory genetic counselling and legal guardian consent per Federal Decree-Law No. 4 of 2016 on Medical Liability and Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Exclusion: Active hemophilia or severe bleeding disorder โ sample collection must be coordinated with the attending hematologist.
- Exclusion: Acute liver failure with INR >2.5 not on anticoagulation โ venous sampling may be deferred.
๐จ Seek Emergency Care Immediately If You Develop:
- Sudden, severe upper abdominal pain with swelling
- New-onset ascites (fluid in the belly) or rapid weight gain
- Yellowing of eyes/skin (jaundice) and confusion
Patient FAQ & Clinical Guidance
1. What is the F5 Gene Budd-Chiari Syndrome NGS Test and who should consider it?
Answer: The test sequences the entire Factor V gene to detect mutations that predispose individuals to hepatic vein thrombosis and Budd-Chiari syndrome, providing a definitive molecular diagnosis for patients with unexplained liver clotting events.
2. How accurate is this genetic test and what sample is required?
Answer: With 99.9% analytical sensitivity and a validated NGS pipeline, the test yields highly reliable results from a simple sample โ whole blood, extracted DNA, or a single drop on an FTA card.
3. Do I need to prepare for the test, and how long until I receive the results?
Answer: No fasting or medication changes are required before sample collection; a genetic counselling session to draw a pedigree chart ensures accurate family risk assessment, and results are delivered in 3 to 4 weeks.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-controlled, and processed under DHA oversight. Clinical safety and patient consent comply with Federal Decree-Law No. 4 of 2016 on Medical Liability.
DHA Facility License Number: 1143 | Physical Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | F5 Gene NGS Test for Budd-Chiari Syndrome |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood, Extracted DNA, or FTA Card (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available) |
| Methodology Used | Next-Generation Sequencing (NGS) โ full gene coding region, โฅ800x depth |
| ICD-10-CM Code | Z13.89 (Encounter for screening for other genetic and chromosomal anomalies) |
| LOINC Code | 21616-1 (Factor V Leiden mutation analysis) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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