Test Price
1,400 AED✅ Home Collection Available
CXCR4 Gene Mutation Analysis in UAE | 1,400 AED | DHA Licensed
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity — ISO-accredited Sanger Sequencing with dual-read validation.
- VIP Mobile Phlebotomy & Cold-Chain Home Collection — Available daily from 8 AM to 11 PM.
- Post-Test Clinical Guidance — Telephonic interpretation by a Consultant Medical Geneticist within 24 hours of report.
- Direct Insurance Billing — WhatsApp verification at +971 54 548 8731 before collection.
Test Overview & Methodology
The CXCR4 gene mutation analysis detects pathogenic variants linked to WHIM syndrome, metastatic cancer predisposition, and hematopoietic stem cell homing defects. Conducted on peripheral blood via Sanger sequencing, this test delivers definitive genotyping with a turnaround of 7–8 working days — essential for personalized oncology and reproductive counseling.
| Parameter | DNA Labs UAE (Sanger Sequencing) | Alternative (NGS Panel) |
|---|---|---|
| Methodology | Sanger Sequencing (Gold Standard for Single Gene) | Next-Generation Sequencing (Multi-Gene) |
| Diagnostic Yield | >99.9% for CXCR4 Point Mutations | 93–98% (Depth-Dependent) |
| Turnaround Time | 7–8 Working Days | 14–21 Working Days |
| Cost (UAE) | 1,400 AED | 2,500 – 4,000 AED |
| Regulatory Compliance | DHA, ISO 9001:2015, UAE PDPL | Varies by Laboratory |
Physician Insight & Safety Protocols
“I always emphasize that a CXCR4 mutation result must be interpreted alongside clinical phenotype and family history. A positive finding can direct life-saving surveillance or hematopoietic stem cell transplant decisions, but a negative result does not exclude all genetic risk — consider whole exome sequencing if suspicion remains high.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠️ Clinical Advisory
Do not discontinue prescribed medication or alter treatment plans without explicit guidance from your treating physician.
Exclusion Criteria & Urgent Referral
- Exclusion criteria: Active hemolysis or recent blood transfusion (within 2 weeks) may compromise DNA quality; schedule collection after recovery.
- Prescription requirement: A valid doctor’s prescription is mandatory, except for pre‑surgical, antenatal genetic counseling, or official travel‑abroad screening — a clinical note is still required.
- ER Red Flags: If you experience sudden severe neutropenia, recurrent infections with hypogammaglobulinemia, or unexplained warts or skin lesions, seek immediate hematology or immunology consultation — do not wait for test results.
- Minor testing: Genetic testing on children under 18 requires legal guardian consent and pediatric specialist referral, in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of CXCR4 gene mutation analysis?
This test definitively identifies germline variants causing WHIM syndrome and somatic mutations influencing cancer stem cell behavior, enabling targeted monitoring, prophylactic interventions, and familial risk stratification.
2. Can the sample be collected at home?
Yes, we provide VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection between 8 AM and 11 PM. A 6-hour fasting period is required for optimal sample quality.
3. How soon will I receive the report and can I discuss it with a doctor?
Your actionable report is delivered in 7–8 working days. Our DHA-licensed Consultant Medical Geneticist will call you within 24 hours to interpret findings and recommend next steps.
UAE Regulatory & Data Privacy Adherence
Compliance & Data Security Framework
Operated under DNA Labs UAE, DHA Facility License #1143. Strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is stored on local encrypted servers.
Methodology aligned with international clinical guidelines. LOINC® code: 81229-3 (CXCR4 gene full mutation analysis).
Clinical & Logistical Metadata
| Test Name | CXCR4 Gene Mutation Analysis |
| Price (AED) | 1,400 AED |
| Turnaround Time | 7–8 Working Days |
| Sample Type / Matrix | Peripheral Whole Blood (3 mL EDTA) |
| Methodology Used | Sanger Sequencing (Gold Standard) |
| ICD-10-CM Code | D81.0 (WHIM syndrome), Z15.89 (Genetic susceptibility to other disease), Z13.79 (Screening for other genetic diseases) |
| LOINC Code | 81229-3 |
| DHA Facility License & Address | License #1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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