Test Price
2,800 AEDโ Home Collection Available
AIP Genetic Test for Pituitary Adenoma (Prolactin-Secreting) in UAE โ 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015-accredited NGS sequencing with full gene coverage and CNV detection.
- Premium Logistics: VIP mobile phlebotomy & temperature-controlled cold-chain home collection (available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary post-test telephonic clinical correlation session with a senior genetic counsellor.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
Comprehensive Germline AIP Mutation Analysis
This next-generation sequencing (NGS) test screens the entire coding region of the AIP gene for germline mutations linked to familial isolated pituitary adenoma (FIPA), particularly prolactin-secreting tumours. Designed for individuals with a personal or family history of pituitary neoplasia, it delivers actionable insights for early surveillance and endocrine management. Pre-test preparation includes a mandatory genetic counselling session to construct a three-generation family pedigree; no dietary restrictions or fasting are required.
| Feature | Our AIP NGS Test | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Technology | Full gene NGS with copy number variant (CNV) detection | Sanger sequencing of selected exons only |
| Sensitivity | >99.9% for SNVs & small indels, plus large rearrangements | ~97% for point mutations; misses large deletions |
| Turnaround Time | 3โ4 Weeks | 6โ8 Weeks typical |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics, I emphasize that a germline AIP mutation is a marker of hereditary risk, not a diagnosis of active disease. This test enables proactive surveillance and informed family planning. However, results must always be interpreted in consultation with an endocrinologist and genetic counsellor to ensure appropriate management." โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403.
Medication Advisory
Do not discontinue prescribed medication (e.g., dopamine agonists like cabergoline) without consulting your doctor. This test guides long-term management but never replaces current therapy.
Exclusion Criteria & Emergency Red Flags
Absolute Exclusions
- Sample not collected in an EDTA tube or haemolysed specimen
- Incomplete clinical history / family pedigree chart
- Patient without informed consent for genetic testing
If You Experience These, Seek ER Care Immediately
- Sudden severe headache with visual loss
- Acute double vision or drooping eyelid
- Loss of consciousness or symptoms of pituitary apoplexy
Patient FAQ & Clinical Guidance
1. What exactly does the AIP genetic test detect, and who should consider it?
Direct Answer: A germline AIP mutation increases risk for hereditary pituitary adenomas, particularly prolactin-secreting tumours, requiring lifelong endocrine surveillance. Individuals with early-onset pituitary adenoma (โค30 years), a family history of pituitary tumours, or unexplained hyperprolactinemia with a pituitary mass are ideal candidates, as recommended by current endocrine society guidelines.
2. How will I receive my results, and what do they mean for my family?
Direct Answer: Your integrated report details whether a pathogenic AIP variant was found, its clinical significance, and personalised screening recommendations for you and at-risk relatives. A positive result enables predictive testing in family members; a negative result reduces but does not entirely eliminate pituitary tumour risk, so regular endocrine check-ups remain essential.
3. Is the home collection service safe and accredited for genetic testing samples?
Direct Answer: Our ISO 9001:2015-certified home collection uses temperature-controlled transport and trained phlebotomists to maintain DNA integrity from vein to sequencer. Blood is drawn in a standard EDTA tube, immediately refrigerated, and delivered to the lab within 4 hours. We follow UAE PDPL data privacy protocols, and your sample is barcoded without personal identifiers to ensure confidentiality.
UAE Regulatory & Data Privacy Adherence
Trust & Compliance Framework
This service operates under the DHA Facility License No. 1143 and complies fully with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Genetic testing is performed on a physicianโs referral only, and all results are securely transmitted via encrypted channels.
Clinical & Logistical Metadata
| Test Name | AIP Genetic Test (Germline Mutation Analysis for Pituitary Adenoma, Prolactin-Secreting) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA tube) |
| Methodology Used | Next-Generation Sequencing (NGS) with full gene coverage and CNV detection |
| ICD-10-CM Code | D35.2, E22.1, Z15.89 |
| LOINC Code | 81696-2 |
| DHA Facility License & Address | License No. 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. Corporate Lab: DNA Labs UAE. |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians