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Test Price

2,800 AED

✅ Home Collection Available

WDR72 Gene Amelogenesis Imperfecta Type IIA3 (AI2A3) Genetic Test in UAE | 2800 AED

Executive Summary & Core Metrics

Diagnostic Accuracy: 99.9% Sensitivity via ISO‑accredited NGS processing (Cert: INT/EGQ/2509DA/3139).

Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily 8 AM – 11 PM.

Clinical Guidance: Complimentary Telephonic Post‑Test Genetic Counselling Session.

Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The WDR72 gene test utilises Next‑Generation Sequencing to diagnose Amelogenesis Imperfecta Type IIA3, a hereditary enamel defect often presenting with dental abnormalities and, in some syndromes, dermatological or skeletal features. This high‑precision assay identifies pathogenic single nucleotide variants and small insertion/deletions, guiding clinical management, genetic counselling, and familial risk assessment.

Feature Our NGS Test (DHA‑Compliant) Closest Alternative (Sanger Panel)
Diagnostic Sensitivity >99.9% (analytical) ~95% (limited to known mutations)
Turnaround Time 3–4 Weeks 2–3 Weeks
Gene Coverage Full coding region + intron‑exon boundaries Selected exonic regions only
Regulatory Standard DHA/MOHAP & ISO 9001:2015, UAE PDPL Often not UAE‑certified

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA ID: 9294403): “Genetic results must be interpreted in the context of full clinical evaluation and three‑generation pedigree analysis. Variants of uncertain significance may require familial segregation studies. Post‑test genetic counselling is essential to understand implications for the patient and at‑risk relatives.”

Advisory & Medication Safety

Medication Notice

Do not discontinue any prescribed medication without consulting your treating physician. Inform the genetic counsellor of all current medications and supplements before sample collection.

Exclusion Criteria & Emergency Red Flags

  • Exclusion: Active febrile illness, severe bleeding disorder (e.g., haemophilia), lack of informed consent, or inability to complete pre‑test genetic counselling.
  • Exclusion: Pregnancy‑related clotting risks are evaluated individually; notify our phlebotomist in advance.
  • ER Red Flags: Signs of infection at the draw site (redness, pus, swelling), prolonged bleeding >10 minutes, or sudden severe anxiety after result disclosure – seek immediate medical attention.

Patient FAQ & Clinical Guidance

1. What does the WDR72 gene test detect and when is it recommended?

The WDR72 NGS test identifies mutations in the WDR72 gene responsible for Amelogenesis Imperfecta Type IIA3, and is recommended for individuals with hypoplastic enamel, unusual tooth discoloration, or a family history of hereditary dental anomalies and associated dermatological/skeletal signs.

2. How accurate is the genetic test and what does the laboratory process involve?

Our NGS platform delivers >99.9% analytical sensitivity and specificity for single nucleotide variants and small indel detection, using a quality‑controlled workflow from DNA extraction through bioinformatics analysis.

3. Are there any risks or special preparation steps before giving the sample?

The DNA test requires a simple blood draw or a drop of blood on an FTA card; a mandatory pre‑genetic counselling session and a three‑generation pedigree chart must be completed to maximise clinical accuracy and result interpretation.

UAE Regulatory & Data Privacy Adherence

Compliance Framework

This service adheres to Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data are stored and processed within the UAE under your explicit consent, with access restricted to authorised clinicians. Clinical safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability.

ISO 9001:2015 Certified | DHA Facility License: 1143 | Support: +971545488731

Clinical & Logistical Metadata

Test Name WDR72 Gene Amelogenesis Imperfecta Type IIA3 (AI2A3) Genetic Test
Price (AED) 2 800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole blood (EDTA) or FTA card
Methodology Used Next‑Generation Sequencing (NGS) – full coding region plus intron‑exon boundaries
ICD-10-CM Code K00.5
LOINC Code 21636-6
DHA Facility License & Lab Address DHA License 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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