Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3โ4 weeks
TNXB Gene Ehlers-Danlos Syndrome Type 3 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary โ 99.9% Diagnostic Sensitivity
- Accuracy Guarantee: ISO 9001:2015 accredited NGS processing delivering 99.9% analytical sensitivity and specificity.
- Premium Logistics: Hospital-grade, ISO-certified cold-chain home collection (8 AM โ 11 PM) with VIP mobile phlebotomy.
- Clinical Guidance: Complimentary post-test telephone consultation with a DHA-licensed Consultant Medical Geneticist for result interpretation.
- Insurance: Direct billing verification via WhatsApp (+971 54 548 8731) before scheduling.
Test Overview & Methodology
This advanced Genetic Test analyses the entire coding region of the TNXB gene to identify pathogenic variants associated with classical-like Ehlers-Danlos syndrome (clEDS), previously classified as type 3 hypermobile EDS in older nomenclature. It provides the highest diagnostic yield for autosomal recessive tenascin-X deficiency using a blood, DNA, or FTA card sample with a turnaround time of 3โ4 weeks.
| Feature | Our TNXB NGS Test | Closest Alternative (Single-gene Sanger) |
|---|---|---|
| Technology | Next Generation Sequencing (NGS) โ complete coverage | Sanger sequencing of selected exons only |
| Variant Detection | SNVs, small indels, and copy number variations | Mainly point mutations, limited CNV |
| Turnaround Time | 3โ4 weeks | 6โ8 weeks |
| Sample Type | Whole blood, extracted DNA, FTA card | Usually DNA only |
Physician Insight & Safety Protocols
โAs a DHA-licensed Consultant Medical Geneticist, I emphasize that a genetic test result is a piece of the diagnostic puzzle. A positive TNXB variant must be interpreted alongside clinical findings; a negative result does not exclude other EDS subtypes. Always discuss your family history and symptoms with your referring physician or genetic counselor.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA: 9294403
Advisory
Do not discontinue any prescribed medication or alter your treatment plan without consulting your doctor. This genetic test is for diagnostic purposes only and does not replace ongoing clinical management. Always adhere to your physician's recommendations.
Exclusion Criteria & Emergency Red Flags
- Not appropriate for individuals who have received an allogeneic bone marrow transplant or recent (less than 4 weeks) blood transfusion โ donor DNA may interfere with results.
- Seek immediate emergency care if you experience sudden, severe joint dislocation with loss of circulation, numbness, or visible deformity.
- If you develop acute skin tearing with uncontrolled bleeding or signs of infection, proceed to the nearest emergency room.
Patient FAQ & Clinical Guidance
1. What does the TNXB gene test diagnose and how does it relate to Ehlers-Danlos syndrome type 3?
This test detects pathogenic variants in the TNXB gene causing classical-like Ehlers-Danlos syndrome, an autosomal recessive condition with overlapping features of hypermobile EDS type 3. Accurate interpretation requires genetic counseling and correlation with clinical findings.
2. How accurate is the NGS method for TNXB testing and what is your quality assurance?
Our ISO 9001:2015 accredited laboratory achieves greater than 99.9% analytical sensitivity and specificity for single nucleotide variants and small indels. Every report is validated by a board-certified molecular geneticist using DHA/MOHAP reference standards.
3. How does the home collection service work and is it safe for genetic testing?
Trained, DHA-licensed phlebotomists arrive between 8 AM and 11 PM with ISO-certified cold-chain transport containers, draw a single blood sample or collect an FTA card, and deliver it directly to our central processing facility without compromising sample integrity.
UAE Regulatory & Data Privacy Adherence
Compliant with UAE Health Data Protection Laws
All genetic data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Book Now via WhatsAppClinical & Logistical Metadata
| Test Name | TNXB Gene Ehlers-Danlos Syndrome Type 3 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 weeks |
| Sample Type / Matrix | Whole blood, extracted DNA, FTA card |
| Methodology Used | Next Generation Sequencing (NGS) |
| ICD-10-CM Code | Q79.6 (Ehlers-Danlos syndrome) |
| LOINC Code | 100309-3 (TNXB gene full sequencing) |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
Preparation Required
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Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians