Test Price
1,800 AED✅ Home Collection Available
Chromosomal Microarray 60K (Products of Conception) in UAE | 1,800 AED | DHA-Licensed Genomic Testing
Starting Price
1,800
AED
Inclusive of POC Tissue Analysis
Executive Summary & Core Metrics
Chromosomal Microarray 60K (Products of Conception) is a high-resolution genomic test that detects submicroscopic chromosomal deletions, duplications, and copy number variants (CNVs) in fetal tissue following miscarriage or stillbirth. With a diagnostic sensitivity of 99.9% via ISO 9001:2015-accredited Agilent 60K microarray processing, this test identifies genetic causes of pregnancy loss that conventional karyotyping cannot visualize. Results are interpreted by DHA-licensed Consultant Medical Geneticist Lina Osama Zaki Quteineh, with post-test telephonic consultation available.
Test Overview & Methodology
Chromosomal Microarray 60K (Products of Conception) is a genome-wide test that detects copy number variants (CNVs), absence of heterozygosity (AOH), mosaicism, and triploidy with resolution down to 100–200 kilobases — far exceeding conventional karyotyping (5–10 Mb). This test is the first-tier diagnostic recommendation according to ACOG, RCOG, and DHA guidelines for recurrent pregnancy loss. The methodology uses Agilent SurePrint G3 Human CGH Microarray 60K with SNP backbone, validated per ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
The test requires Products of Conception tissue collected in sterile saline or RPMI medium (never formalin) and transported at 2–8°C. Optional maternal EDTA blood may be drawn concurrently for confirmation studies; heparin tubes are prohibited.
| Feature | Our Test: CMA 60K POC | Conventional Karyotyping | FISH Panel (Limited Probes) |
|---|---|---|---|
| Resolution | ~100–200 kb (Genome-Wide) | 5–10 Mb (Microscope-Visible Only) | Targeted Loci Only (3–5 Regions) |
| Detection Scope | CNVs, AOH, Mosaicism, Triploidy | Aneuploidy, Large Rearrangements | Pre-Selected Aneuploidies Only |
| Sample Requirement | POC Tissue (Sterile Saline/RPMI) + Optional Maternal EDTA Blood | Viable Cultured Cells Required | Fresh or Fixed Tissue |
| Turnaround Time | 15–20 Days | 21–28 Days (Culture-Dependent) | 7–10 Days (Limited Scope) |
| Failure Rate | <2% (No Culture Required) | 20–40% (Culture Failure Common) | 5–15% |
Methodology: Agilent SurePrint G3 Human CGH Microarray 60K | Platform validated per ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | LOINC: 62356-1 — loinc.org/62356-1
Physician Insight & Safety Protocols
“Chromosomal Microarray on Products of Conception provides definitive answers for families experiencing pregnancy loss. This test identifies pathogenic genomic imbalances with high sensitivity, but every finding must be correlated with maternal history, parental karyotypes when indicated, and comprehensive genetic counseling. No single laboratory result replaces the clinical judgment of your treating physician. Our goal is to offer clarity and support for informed reproductive decisions.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Medication Advisory
Do not discontinue any prescribed medication, hormonal therapy, or anticoagulant regimen without consulting your attending physician. Chromosomal Microarray POC testing does not assess maternal health status, and abrupt medication changes may pose serious clinical risk. For patients on progesterone supplementation, low-molecular-weight heparin, or antihypertensive therapy following pregnancy loss, coordinate all medication adjustments exclusively through your DHA-licensed obstetrician.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria for POC Sample Collection:
- Tissue fixed in formalin or any aldehyde-based preservative — only sterile saline or RPMI medium accepted
- POC specimen collected >72 hours prior without continuous refrigeration (2–8°C)
- Heavily necrotic or macerated tissue with no identifiable chorionic villi on gross examination
- Maternal blood collected in heparin tube (green-top) — use EDTA (lavender-top) only
- Active maternal coagulopathy or severe anemia (Hb <7 g/dL) relative contraindication for maternal phlebotomy
Emergency Red Flags — Seek Immediate Medical Attention:
- Heavy vaginal bleeding soaking >2 pads/hour for 2 consecutive hours
- Fever >38.5°C (101.3°F) with chills or foul-smelling vaginal discharge
- Severe pelvic or abdominal pain unrelieved by prescribed analgesia
- Syncope, dizziness, or tachycardia suggesting hemodynamic instability
- Signs of sepsis: confusion, rapid breathing, mottled skin, or decreased urine output
These symptoms may indicate retained products of conception, endometritis, or hemorrhage — all require emergency department evaluation regardless of microarray testing status. Call 998 for UAE ambulance services immediately if symptoms are severe.
Patient FAQ & Clinical Guidance
1. What does Chromosomal Microarray 60K POC detect that standard karyotyping misses?
Chromosomal Microarray 60K detects submicroscopic deletions and duplications as small as 100 kilobases across all 24 chromosomes, identifying pathogenic copy number variants responsible for pregnancy loss that conventional karyotyping — limited to 5–10 megabase resolution — cannot visualize. Additionally, CMA detects areas of homozygosity (AOH) suggestive of uniparental disomy, mosaicism above approximately 10–15%, and triploidy when combined with SNP probe analysis. In clinical cohorts, CMA identifies a clinically significant genetic cause in 8–13% of miscarriage specimens with normal karyotypes, making it the first-tier diagnostic test recommended by ACOG, RCOG, and DHA for Products of Conception analysis in recurrent pregnancy loss.
2. How should the Products of Conception sample be collected and transported for optimal results?
Products of Conception tissue must be collected in a sterile container with normal saline or RPMI transport medium — never formalin or any fixative — and transported to our ISO-certified laboratory at 2–8°C within 24 hours of collection for optimal DNA integrity. Collection is performed by a DHA-licensed healthcare provider in a hospital or clinical setting; no home collection is available for tissue specimens. If maternal blood is required for confirmation studies, an EDTA (lavender-top) tube is drawn concurrently in the same facility. Avoid heparin-based anticoagulants as they inhibit downstream enzymatic reactions. Specimens are accessioned immediately upon receipt, and DNA extraction begins within 4 hours to minimize degradation. Incomplete or improperly collected specimens will be rejected with immediate notification via SMS and phone call to the ordering physician.
3. Is a doctor's prescription required, and how does insurance coverage work in the UAE?
Yes, a valid prescription from a DHA-licensed Gynecologist, Obstetrician, or Clinical Geneticist is required for Chromosomal Microarray 60K POC testing. Our dedicated insurance verification team processes direct billing approvals via WhatsApp at +971 54 548 8731 within two hours. Prescription requirements may be waived under specific clinical protocols for post-surgical pathology specimens, established recurrent pregnancy loss cases under MOHAP-approved fertility programs, and pre-travel genetic counseling packages — all subject to our Clinical Advisory Board review. We accept all major UAE medical insurance networks including Daman, Thiqa, Neuron, MetLife, AXA, and Bupa. Self-pay patients receive a detailed itemized invoice suitable for insurance reimbursement claims. For minors (patients under 18), testing is governed by UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, requiring documented parental or legal guardian consent.
UAE Regulatory & Data Privacy Adherence
This service operates in full compliance with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for genetic data privacy, and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for electronic health records. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. All genetic data is stored on encrypted, UAE-sovereign servers with access restricted to authorized clinical personnel. Patient results are released exclusively to the ordering physician and the patient through secure, authenticated channels.
Clinical & Logistical Metadata
| Test Name | Chromosomal Microarray 60K (Products of Conception) |
| Price (AED) | 1,800 |
| Turnaround Time | 15–20 Days |
| Sample Type / Matrix | POC Tissue (Sterile Saline/RPMI) + Optional Maternal EDTA Blood |
| Methodology Used | Agilent SurePrint G3 Human CGH Microarray 60K with SNP backbone |
| ICD-10-CM Code | O02.1, N96, Z13.79 |
| LOINC Code | 62356-1 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab Branding: DNA Labs UAE |
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