Test Price
2,200 AEDโ Home Collection Available
Chromosomal Microarray 315K (AF/CVS/CB/POC/PB) in UAE โ 2,200 AED โ DHA Licensed Diagnostic Genomics
Executive Summary & Core Metrics
The 315K Chromosomal Microarray delivers 99.9% diagnostic sensitivity for detecting clinically significant copy number variants, regions of homozygosity, and mosaic abnormalities across the entire genome at 50โ100 kb resolution. This test is the gold-standard platform for fetal anomaly confirmation, stillbirth investigation, and recurrent pregnancy loss evaluation. All invasive samples (amniotic fluid, CVS, cord blood, POC) are collected under strict hospital supervision; peripheral blood draws follow standard venipuncture protocols. Results are reported within 7โ9 working days with an integrated expert interpretation.
Test Overview & Methodology
This high-density SNP microarray detects clinically relevant chromosomal microdeletions, duplications, and regions of homozygosity across the entire genome at a resolution of 50โ100 kb. It is the gold-standard diagnostic tool for fetal anomaly confirmation and investigation of pregnancy loss, delivering results in just 7โ9 working days. The assay uses Affymetrix CytoScan 315K technology with whole-genome amplification, fragmentation, labeling, hybridization, and high-resolution scanning followed by bioinformatic analysis against reference genome GRCh38.
| Feature | CytoScan 315K Microarray (Our Test) | Standard Karyotype | NIPT (cfDNA) |
|---|---|---|---|
| Method | SNP Microarray (Affymetrix CytoScan) | G-banding Microscopy | Massively Parallel Sequencing of cell-free DNA |
| Genome-wide Resolution | 50โ100 kb (clinical significance) | 5โ10 Mb | Focused on chromosomes 21,18,13 + sex aneuploidy |
| Diagnostic Type | Diagnostic โ detects CNVs & LOH | Diagnostic โ large structural abnormalities | Screening only (requires invasive confirmation) |
| Turnaround Time | 7โ9 working days | 10โ14 calendar days | 5โ7 working days |
| Sample Types | Amniotic Fluid, CVS, Cord Blood, POC, Peripheral Blood | Amniocytes, CVS, POC | Maternal blood only |
Physician Insight & Safety Protocols
โIn my practice, I see families grappling with uncertainty after an abnormal ultrasound or a pregnancy loss. The 315K microarray provides a definitive molecular answer that standard karyotyping may miss, especially for submicroscopic deletions and duplications. I always emphasise that a positive finding must be correlated with fetal imaging, parental studies, and a thorough discussion of recurrence risks and reproductive options. Our role is to translate complex genomic data into clear, actionable guidance for each family.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Precautions Before Sample Collection
โ ๏ธ Important Clinical Advisory
Do not discontinue or alter any prescribed medication before sample collection without explicit approval from your treating physician. Certain anticoagulants may require temporary cessation only under medical supervision, but never stop blood thinners on your own. For invasive procedures (amniocentesis, CVS, cord blood), your obstetrician will evaluate bleeding risk and placental position prior to proceeding.
Exclusion Criteria & Emergency Red Flags
- Invasive prenatal sampling (amniocentesis/CVS): Not performed if there is active genital infection, uncontrolled bleeding disorder, or significant vaginal bleeding.
- Peripheral blood collection: Safe for most; contraindicated only in extreme cases of phlebotomy risk.
- Seek emergency care immediately if after an invasive procedure you experience: severe abdominal pain, fever โฅ38ยฐC, heavy vaginal bleeding (soaking a pad per hour), or sudden fluid leakage โ these may indicate rare complications like chorioamnionitis or membrane rupture.
Patient FAQ & Clinical Guidance
1. What is the turnaround time for Chromosomal Microarray 315K results?
Snippet: Your sample is analyzed using ultra-dense SNP microarrays, delivering comprehensive chromosomal copy number results within seven to nine working days. This includes DNA extraction, hybridization, scanning, and expert bioinformatic interpretation. Our laboratory communicates preliminary findings immediately if a clinically actionable result is detected, allowing your doctor to make rapid pregnancy management decisions.
2. Is this microarray required instead of NIPT during pregnancy?
Snippet: This microarray is a diagnostic test that identifies clinically significant microdeletions and duplications missed by standard NIPT screening. While NIPT is an excellent screening tool for common trisomies, it cannot detect hundreds of pathogenic copy number variants. If fetal anomalies are seen on ultrasound, or after a pregnancy loss, the 315K microarray provides a definitive genomic diagnosis. In contrast, NIPT is not recommended as a standalone diagnostic.
3. Does health insurance cover Chromosomal Microarray 315K testing in Dubai?
Snippet: Most UAE insurers cover microarray testing when medically necessary; our team verifies coverage directly with your insurer via WhatsApp. We pre-approve claims for indications such as advanced maternal age, abnormal ultrasound, recurrent pregnancy loss, or suspected microdeletion syndromes. Our billing department communicates with all major UAE payers (Daman, AXA, Oman Insurance, etc.) to minimize out-of-pocket expenses.
4. What type of sample is required for the 315K microarray?
Snippet: Your referring specialist will determine the appropriate specimen โ amniotic fluid, chorionic villi, cord blood, products of conception, or peripheral blood. Invasive samples (AF, CVS, CB, POC) are collected only within a hospital setting by an experienced obstetrician. Peripheral blood can be drawn at a clinic or hospital laboratory. A valid physician prescription is generally required; for emergency surgical clearance, confirmed pregnancy, or travel certificates, prescription requirements may be waived per local DHA regulations.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance Framework
All genetic data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory holds ISO 9001:2015 certification (INT/EGQ/2509DA/3139) and operates under DHA Facility License 1143.
DNA Labs UAE is committed to the highest standards of genomic data confidentiality, secure transmission, and ethical reporting. All results are released only to the referring physician or authorized healthcare provider after appropriate genetic counseling is offered.
Clinical & Logistical Metadata
| Test Name | Chromosomal Microarray 315K (AF/CVS/CB/POC/PB) |
| Price (AED) | 2,200 AED |
| Turnaround Time | 7โ9 working days |
| Sample Type / Matrix | Amniotic Fluid, Chorionic Villus Sampling (CVS), Cord Blood, Products of Conception (POC), Peripheral Blood |
| Methodology Used | High-density SNP Microarray (Affymetrix CytoScan 315K) |
| ICD-10-CM Code | Z31.5 (Encounter for genetic counseling) |
| LOINC Code | 82121-8 (Chromosomal microarray analysis) |
| DHA Facility License & Laboratory Address | License 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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