Test Price
2,800 AED✅ Home Collection Available
VCL Gene Dilated Cardiomyopathy Type 1W Next-Generation Sequencing (NGS) Genetic Test in UAE | 2800 AED | DHA-Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by qualified healthcare professionals.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This targeted Next-Generation Sequencing (NGS) panel comprehensively analyzes the entire coding region of the VCL gene to detect pathogenic variants responsible for dilated cardiomyopathy type 1W, a hereditary disorder of the heart muscle. Our DHA-licensed facility delivers a clinically actionable report within 3–4 weeks, empowering cardiologists and clinical geneticists to implement precision management plans.
| Aspect | Our Test (VCL NGS) | Closest Alternative (Single-Gene Sanger Sequencing) |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) – full gene plus flanking intronic regions | Sanger sequencing of limited exons, missing deep intronic variants |
| Detection Rate | >99% of reported pathogenic variants (including copy number variants) | ~85% for point mutations; rarely detects large deletions/duplications |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
Physician Insight & Safety Protocols
“The VCL gene test is a critical tool for confirming a genetic cause of dilated cardiomyopathy. Accurate classification of variants requires integration with the patient’s clinical presentation and family history. A positive result warrants cascade screening for first-degree relatives, while a negative result does not exclude other genetic etiologies. Genetic counselling before and after testing is essential for informed decision-making.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory Note
⚠️ Do not discontinue any prescribed cardiac or other medication without consulting your treating physician. This test is intended for risk stratification and diagnostic clarification, not for immediate therapy adjustments. Always follow your cardiologist’s recommendations.
Patient Safety & Exclusion Criteria
- Exclusion Criteria: Active myocarditis, recent myocardial infarction (within 4 weeks), inability to provide written informed consent for genetic testing, or concurrent severe systemic illness that would delay safe sample collection.
- Emergency Red Flags: If you experience sudden chest pain, syncope (fainting), severe shortness of breath, or palpitations with dizziness, call 998 immediately or go to the nearest emergency department. Do not wait for genetic results.
- Pre‑Test Requirement: A clinical genetic counselling session must be completed prior to sample collection to construct a detailed family pedigree and document affected relatives (VCL-related cardiomyopathy).
Patient FAQ & Clinical Guidance
1. What exactly does the VCL gene test detect, and why is it important for cardiomyopathy?
This test identifies pathogenic mutations in the VCL gene that disrupt the heart muscle's structural protein vinculin, directly causing dilated cardiomyopathy type 1W. Detecting such mutations allows cardiologists to confirm a genetic diagnosis, guide family screening, and tailor long-term surveillance for arrhythmias and heart failure.
2. What are the sample types accepted for this test, and how is the collection done?
We accept whole blood, extracted DNA, or a single drop of blood on an FTA card, collected conveniently at your home or office by our ISO-certified VIP mobile phlebotomy team. The sample is immediately stabilized in a cold-chain system and transported to our facility, where NGS sequencing is performed to achieve 99.9% analytical sensitivity.
3. How do the results impact my family, and what steps should I take afterwards?
A positive VCL result indicates a heritable mutation that may be shared by first‑degree relatives, necessitating predictive genetic testing for at‑risk family members. We provide a comprehensive telephonic counselling session to explain the findings and connect you with a specialist for cascade family screening and cardiology follow‑up.
UAE Regulatory & Data Privacy Adherence
This laboratory complies with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring all genetic data is processed lawfully, stored securely, and used only for diagnostic purposes with explicit patient consent.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – regulating the electronic handling of health information and telemedicine interactions.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – governing clinical testing safety and patient consent procedures.
Clinical & Logistical Metadata
| Test Name | VCL Gene Dilated Cardiomyopathy Type 1W Next-Generation Sequencing (NGS) Genetic Test |
| Price (AED) | 2800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card (Dried Blood Spot) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full gene coding region and flanking intronic regions |
| ICD-10-CM Code | I42.0 (Dilated cardiomyopathy) |
| LOINC Code | 93239-3 (VCL gene full sequencing) |
| DHA Facility License & Laboratory Address | DHA Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Lab: DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians