Test Price
2,800 AED✅ Home Collection Available
TRDN Gene (Catecholaminergic Polymorphic Ventricular Tachycardia Type 5) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO-accredited NGS processing with Sanger confirmation of all pathogenic variants.
- Premium Logistics: VIP Mobile Phlebotomy & temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic post-test clinical guidance provided by a DHA-licensed medical geneticist for comprehensive result interpretation.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731 (instant eligibility check).
Test Overview & Methodology
The TRDN gene test is a definitive next-generation sequencing (NGS) assay that identifies pathogenic variants in the triadin gene, responsible for catecholaminergic polymorphic ventricular tachycardia type 5 (CPVT5). This inherited arrhythmia can cause sudden cardiac death in young individuals; the test empowers cardiologists and medical geneticists to guide implantable defibrillator decisions and lifestyle modifications with high precision.
| Feature | Our TRDN NGS Test | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Precision | Whole-gene sequencing + CNV detection, 99.9% analytical sensitivity | Exon-by-exon Sanger; may miss large deletions |
| Methodology | NGS with Illumina NovaSeq, bioinformatic pipeline validated to ACMG guidelines | Sanger sequencing, manual curation |
| Turnaround Time | 3–4 Weeks | 6–10 Weeks (often outsourced) |
Physician Insight & Safety Protocols
"This genetic test identifies pathogenic variants in the triadin gene, which are associated with catecholaminergic polymorphic ventricular tachycardia type 5. Interpretation must be performed by a clinical geneticist in the context of detailed family history and clinical phenotype. A negative TRDN result does not exclude other genetic causes of CPVT; comprehensive cardiac gene panel testing may be considered. The decision to proceed with medical therapy or an implantable cardioverter-defibrillator remains multidisciplinary, guided by symptom burden, arrhythmic risk, and genetic findings."
— Ms. Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory & Medication Warning
⚠️ Important
Do not discontinue prescribed antiarrhythmic medications or beta-blockers without consulting your doctor. Abrupt cessation may increase the risk of life-threatening arrhythmias.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients who have undergone allogeneic bone marrow transplantation within 90 days (donor DNA interference).
- Exclusion: Individuals under 18 years without a court-approved legal guardian's consent, per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Red Flag: If you experience syncope (fainting), chest pain, or palpitations during exercise, seek emergency medical attention immediately — do not await test results.
- Red Flag: A positive TRDN pathogenic variant in a child requires urgent evaluation of all first-degree relatives and avoidance of competitive sports until cleared by a cardiologist.
Pre-test genetic counselling is mandatory: a certified genetic counsellor will draw a detailed pedigree chart to identify at-risk family members before sample collection.
Patient FAQ & Clinical Guidance
1. What does the TRDN genetic test detect, and why is it crucial for athletes?
The TRDN gene test identifies pathogenic variants causing catecholaminergic polymorphic ventricular tachycardia type 5, a potentially lethal arrhythmia triggered by adrenaline. For athletes and young individuals, a positive result mandates immediate restriction from competitive sports and initiation of beta-blocker therapy to prevent sudden cardiac arrest.
2. How is the sample collected, and what pre-test steps are required?
A simple peripheral blood sample (3–5 mL) is collected by a DHA-licensed home-visit phlebotomist using a validated cold-chain kit. Alternatively, a dried blood spot (FTA card) can be used. Before collection, you must complete a mandatory genetic counselling session to document a three-generation pedigree and understand the implications of possible findings, in full compliance with UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
3. Will my health insurance cover this 2800 AED TRDN test in UAE?
Many UAE insurance plans now cover advanced genetic cardiac testing when pre-authorized by a consultant cardiologist or medical geneticist. Our team verifies your coverage instantly via WhatsApp (+971 54 548 8731) and provides a direct billing option, minimizing out-of-pocket delays.
UAE Regulatory & Data Privacy Adherence
Privacy & Compliance
This diagnostic service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is securely encrypted, stored within UAE servers, and accessed only by authorized medical personnel. Patient consent is obtained and documented in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | TRDN Gene (Catecholaminergic Polymorphic Ventricular Tachycardia Type 5) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (3-5 mL) or dried blood spot (FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | I47.2 |
| LOINC Code | 21637-4 |
| DHA Facility License & Laboratory Address | License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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