Test Price
2,800 AED✅ Home Collection Available
RTN3 Gene Alzheimer’s Disease & RTN3-Related Genetic Test | DNA Labs UAE | 2,800 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited next-generation sequencing (NGS) processing, ensuring every RTN3 variant is identified with clinical-grade precision.
Premium Logistics: VIP Mobile Phlebotomy and Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all Emirates, with ISO-certified transport.
Clinical Guidance: Telephonic post-test clinical guidance with a DHA-registered Consultant Medical Genetics to interpret results, discuss risk, and advise on next steps.
Insurance: Direct billing verification via WhatsApp at +971 54 548 8731; pre-approval processed within 2 hours during business days.
Test Overview & Methodology
This advanced NGS test sequences the entire coding region of the RTN3 gene, identifying pathogenic variants linked to elevated Alzheimer's disease (AD) risk. It is designed for neurologists, clinical geneticists, and genetic counsellors to inform familial risk stratification, early lifestyle interventions, and personalised monitoring plans under UAE's stringent genetic testing regulations.
| Feature | Our RTN3 NGS Test (UAE) | Standard APOE Genotyping |
|---|---|---|
| Methodology | Next Generation Sequencing (NGS) – full RTN3 gene with CNV detection | PCR-based targeted SNP analysis (APOE ε2/ε3/ε4) |
| Turnaround Time | 3–4 Weeks | 1–2 Weeks |
| Clinical Depth | Identifies rare RTN3 mutations with Alzheimer's association, enabling precise familial screening | Common risk-allele typing; misses rare pathogenic variants |
| UAE Regulatory Alignment | Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields | May not meet full hereditary neurological genetic counselling requirements |
| Price (AED) | 2,800 | 1,200 – 1,800 |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics, I emphasise that the RTN3 genetic test is a risk stratification tool, not a definitive diagnostic marker. Clinical correlation with neuropsychological assessments, neuroimaging, and family history remains essential. Patients often arrive with heightened concern; I counsel them that knowledge of their genetic status can empower proactive brain-health strategies, but results must always be interpreted alongside their personal medical context. No test result should prompt abrupt medication changes without specialist guidance."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Clinical Advisory
Do not discontinue or modify any prescribed medication, including acetylcholinesterase inhibitors or antidepressants, without consulting your treating physician. A genetic finding does not equate to immediate clinical manifestation.
Exclusion Criteria & Emergency Red Flags
- This test is not for acute diagnostic purposes. If you or a family member experiences sudden confusion, hallucinations, severe agitation, or suicidal ideation, seek emergency care immediately.
- Minors (below 18 years) are excluded unless accompanied by a legal guardian and a court order compliant with UAE genetic testing regulations; pre-test counselling is mandatory.
- Patients on anticoagulants (e.g., warfarin) must inform the phlebotomist prior to blood collection; an alternative sample (extracted DNA or FTA card) may be advised.
- Invalid for individuals who have received allogeneic bone marrow transplant or recent blood transfusion (within 2 weeks) – donor DNA may interfere.
- If you experience chest pain, neurological deficits, or uncontrolled bleeding after sample collection, call 998 immediately.
Patient FAQ & Clinical Guidance
1. What is the clinical value of RTN3 genetic testing for Alzheimer's disease?
RTN3 gene testing reveals inherited mutations that heighten Alzheimer's risk, guiding early intervention and family planning. Beyond risk evaluation, the report enables your neurologist to tailor cognitive screening frequencies and consider participation in prevention trials. A certified Consultant Medical Genetics will explain the results in the context of your complete medical history.
2. How is the sample collected and how soon will I receive my results?
One blood draw collected at home provides comprehensive NGS results in just 3–4 weeks. Our DHA-licensed mobile phlebotomist arrives at your preferred location (8 AM–11 PM), using cold-chain transport to the laboratory. You may also submit pre-extracted DNA or a single drop of blood on an FTA card, following the same processing timeline.
3. Are my genetic data and results kept confidential under UAE law?
Your genetic data is encrypted, stored under UAE PDPL, and never shared without explicit DHA-compliant consent. Our laboratory adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection and ISO 9001:2015 standards; data retention policies limit access to authorised healthcare professionals only. Any data sharing for research requires a separate, revocable consent form.
4. Can I get this test done if I have a family history of Alzheimer's but no symptoms?
Yes, this test is particularly valuable for asymptomatic individuals with a strong family history of early-onset Alzheimer's. A positive result enables proactive monitoring and lifestyle modifications. Pre-test and post-test genetic counselling with our Consultant Medical Genetics is mandatory to ensure informed decision-making and psychological preparedness.
UAE Regulatory & Data Privacy Adherence
Legal & Privacy Framework
This test and the handling of all associated genetic data are conducted in full compliance with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring your genetic information is encrypted, access-controlled, and processed only with your explicit consent.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing the secure electronic storage and transmission of health records.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – establishing the standards for clinical safety, patient consent, and professional accountability in genetic testing.
Your results are stored on UAE-based secure servers with role-based access limited to your treating physician and the authorised laboratory team. No data is transferred internationally without your explicit written authorisation.
Clinical & Logistical Metadata
| Test Name | RTN3 Gene Alzheimer's Disease & RTN3-Related Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection) |
| Methodology Used | Next Generation Sequencing (NGS) – Full gene sequencing with CNV detection |
| ICD-10-CM Code | G30.9 (Alzheimer's disease, unspecified), Z13.89 (Encounter for screening for other genetic diseases) |
| LOINC Code | 55233-1 (Genetic analysis of a gene panel for Alzheimer disease) |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians