Test Price
2,800 AED✅ Home Collection Available
SORL1 Gene Alzheimer’s Disease (Early-Onset, Autosomal Dominant) Genetic Test in UAE – 2,800 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing.
Premium Logistics: VIP mobile phlebotomy & temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
Clinical Guidance: Telephonic post-test genetic counselling.
Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The SORL1 genetic test utilizes next-generation sequencing (NGS) to detect pathogenic variants in the SORL1 gene, which cause autosomal dominant early-onset Alzheimer’s disease. This highly precise test aids neurologists and genetic counsellors in confirming molecular diagnosis, guiding clinical management, and assessing familial risk.
| Parameter | Our SORL1 NGS Test | Closest Alternative (APOE/Limited Panel) |
|---|---|---|
| Diagnostic Accuracy | 99.9% Sensitivity, Full Gene Coverage | ~95% Sensitivity, Limited Loci |
| Methodology | Next-Generation Sequencing (NGS) – ISO 9001:2015 Validated | Genotyping Arrays / Sanger Sequencing |
| Turnaround Time | 3 – 4 Weeks | 1 – 2 Weeks |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I emphasize that this genetic test must be interpreted alongside a comprehensive neurological evaluation, family history, and genetic counselling. A positive result indicates a pathogenic mutation and increased risk, but does not by itself diagnose Alzheimer’s disease. Please ensure all prescribed medications are continued as directed.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Medical Advisory
Do not discontinue any prescribed medication without consulting your treating physician. All current treatments must be maintained as directed by your neurologist.
Exclusion Criteria & Safety Red Flags
- Individuals under 18 years (as per UAE Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Inability to provide written informed consent after pre-test genetic counselling.
- Lack of a mandatory pre-test genetic counselling session.
- Emergency red flags: acute severe memory loss, hallucinations, or suicidal ideation – seek immediate medical attention.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of the SORL1 gene test for early-onset Alzheimer’s?
SORL1 genetic testing with next-generation sequencing identifies mutations responsible for early-onset autosomal dominant Alzheimer’s disease, aiding diagnosis and genetic counselling. It supports prognosis refinement, eligibility for clinical trials, and cascade testing for at-risk family members.
2. What is required before taking the SORL1 test?
A mandatory pre-test genetic counselling session is required to draw a family pedigree and collect comprehensive clinical history. Acceptable sample types include peripheral whole blood, extracted DNA, or dried blood spot (FTA card).
3. How can I get the test done at home in the UAE?
Schedule VIP home collection via WhatsApp with cold-chain transport from 8 AM until 11 PM. The ISO-certified mobile phlebotomy team collects the sample under validated temperature-controlled conditions. Verify insurance coverage via WhatsApp +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This test complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability. Laboratory DHA license: 1143. ISO 9001:2015 certified – Cert: INT/EGQ/2509DA/3139.
Clinical & Logistical Metadata
| Test Name | SORL1 Gene Alzheimer’s Disease (Early-Onset, Autosomal Dominant) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Peripheral whole blood, extracted DNA, or dried blood spot (FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | G30.0 |
| LOINC Code | 21705-3 |
| DHA Facility License & Laboratory Address | DHA License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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