Test Price
800 AED✅ Home Collection Available
Factor II Mutation Screening (F2 – G20210A) – 800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Test Overview & Methodology
Factor II Mutation Screening (F2 – G20210A) is a molecular genetic test that detects the prothrombin gene G20210A variant, a well-established inherited risk factor for venous thromboembolism. This analysis employs endpoint polymerase chain reaction (PCR) coupled with restriction fragment length polymorphism (RFLP) analysis, validated under ISO 9001:2015 standards to ensure >99.9% analytical sensitivity and specificity.
| Feature | Our Test (Gold Standard) | Closest Alternative |
|---|---|---|
| Precision | >99.9% analytical sensitivity & specificity | ~98% sensitivity (NGS panels) |
| Methodology | Endpoint PCR + RFLP (ISO-validated) | Multiplex PCR / NGS (no ISO-specific validation) |
| Turnaround Time | 3–4 working days | 5–10 working days |
| Price | 800 AED (inclusive) | Often >1,200 AED |
Physician Insight & Safety Protocols
“Genetic thrombophilia screening must always be correlated with a complete clinical history and coagulation studies. A positive result does not guarantee a clot, and a negative result does not exclude all thrombotic risks. It is essential to interpret this test in the context of your personal and family history, and I strongly advise continuing any prescribed anticoagulant therapy until you discuss the results with your managing physician.”
— Dr. Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA License 9294403
Safety Advisory
Do not discontinue prescribed anticoagulant therapy without consulting your physician. Abrupt cessation may increase the risk of thromboembolic events.
Exclusion Criteria & Emergency Red Flags
- Minors under 18 years without legal guardian consent (in compliance with UAE Federal Law No. 2 of 2019 and PDPL).
- Individuals unable to give informed consent due to cognitive impairment.
- Acute thrombosis with recent initiation of anticoagulation – consult clinician before drawing.
- Known active bleeding or severe coagulopathy that precludes venipuncture.
Seek immediate emergency care if you experience:
- Sudden leg pain, swelling, redness, or warmth (possible deep vein thrombosis).
- Sharp chest pain, shortness of breath, rapid heart rate, or coughing blood (signs of pulmonary embolism).
Patient FAQ & Clinical Guidance
1. What does Factor II (G20210A) mutation screening detect?
It identifies the inherited prothrombin gene G20210A mutation, a major risk factor for venous thromboembolism. The test helps evaluate personal and family history of blood clots, guiding prophylactic measures and treatment decisions in high-risk individuals.
2. Why is this test recommended before surgery or pregnancy?
This screening identifies inherited thrombophilia to specifically mitigate high perioperative and pregnancy-related venous thromboembolism risk. It enables personalized anticoagulation plans and careful monitoring during and after surgery or throughout pregnancy.
3. How should I prepare for the Factor II mutation test?
No fasting is required. Simply provide a blood sample with a valid doctor’s prescription unless exempt. Peripheral blood is drawn using standard venipuncture; results are typically available within 3–4 working days. A prescription is not required for surgical cases, pregnancy-related testing, or travel abroad screening, as these are exempt per DHA guidance.
UAE Regulatory & Data Privacy Adherence
This test is fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is processed, stored, and transmitted in accordance with these regulations, ensuring strict confidentiality and security. Clinical laboratory operations adhere to DHA licensing requirements and ISO 9001:2015 quality management systems.
Clinical & Logistical Metadata
| Test Name | Factor II Mutation (F2 – G20210A) Screening |
| Price (AED) | 800 |
| Turnaround Time | 3–4 working days |
| Sample Type / Matrix | Peripheral blood (whole blood) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM. |
| Methodology Used | Endpoint PCR + RFLP (ISO‑validated) |
| ICD-10-CM Code | Z13.79 (Encounter for screening for other genetic and chromosomal anomalies) |
| LOINC Code | 21654-8 (Prothrombin gene mutation analysis) |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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