Test Price
800 AED✅ Home Collection Available
Thalassemia Alpha Mutation Analysis in UAE | 800 AED | 2026 DHA Guidelines
Comprehensive genetic profiling with PCR & MLPA technology · ISO 9001:2015 accredited
تحليل طفرة ألفا ثلاسيميا في الإمارات | 800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – الملخص التنفيذي
يقدم هذا الاختبار تحليلًا دقيقًا لطفرة جين ألفا جلوبين، المعتمد من هيئة الصحة بدبي، مع خدمة سحب منزلي متميزة ودقة تشخيصية بنسبة 99.9%، مما يدعم اتخاذ قرارات سريرية وأسرية مستنيرة.
📋 Test Overview
This advanced molecular assay identifies deletions and point mutations in the HBA1 and HBA2 genes using gold‑standard PCR and MLPA, enabling precise diagnosis of alpha thalassemia syndromes, silent carrier status, and hemoglobin H disease. يكشف التحليل الطفرات في جينات ألفا جلوبين لتأكيد التشخيص وتصنيف حامل المرض أو الإصابة بدقة متناهية.
| Feature | Our Test (Alpha Mutation Analysis) | Closest Alternative (Hb Electrophoresis/HPLC) |
|---|---|---|
| Precision | Gene-level deletion/duplication resolution | Protein-level only; misses silent carriers |
| Methodology | MLPA + PCR (Multiplex Ligation‑dependent Probe Amplification) | Hemoglobin fraction quantification |
| Speed (TAT) | Sample Mon by 9 am → Report Fri | Often next day but limited sensitivity |
| Clinical Utility | Confirms alpha-thal trait, HbH disease, genetic counseling | Screen only; false negatives in alpha thal |
👨⚕️ Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA License: 61713011) notes: “While this assay provides definitive genetic evidence of alpha globin mutations, clinical findings, complete blood count, and family studies remain essential for full interpretation. I encourage you to review results together with a hematologist or genetic counsellor to understand inheritance risks and disease management. Please remember that this test supports—but does not replace—your ongoing clinical care and monitoring.”
⛔ Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Any adjustment of iron chelation or transfusion therapy should be supervised by your treating physician.
⚠️ Exclusion Criteria & ER Red Flags
- Exclusion: Patient refusal, incomplete Genomics Clinical Information Requisition Form (Form 20), hemodynamic instability precluding safe venipuncture, severe coagulopathy without physician clearance.
- ER Red Flags: If you experience sudden severe anemia symptoms – fainting, chest pain, difficulty breathing, or profound pallor – seek emergency care immediately and do not wait for results.
- Home collection is not performed if the patient has active bleeding or is in an acute medical crisis; the team will advise hospital referral.
❓ Frequent Clinical Questions – الأسئلة الشائعة
Q: What exactly does the Alpha Thalassemia Mutation Analysis detect?
س: ما الذي يكشفه تحليل طفرة ألفا ثلاسيميا بالضبط؟
Alpha Thalassemia Mutation Analysis detects HBA1/HBA2 gene mutations, confirming diagnosis and carrier status for informed decisions. It identifies common deletions (‑‑SEA, ‑α3.7, ‑α4.2) and point mutations in the alpha globin gene cluster, distinguishing silent carriers, alpha thalassemia trait, hemoglobin H disease, and hydrops fetalis. The multiplex ligation‑dependent probe amplification (MLPA) technique ensures high sensitivity even when standard electrophoresis fails.
يحدد تحليل طفرة ألفا ثلاسيميا الطفرات في جينات HBA1/HBA2 لتأكيد التشخيص وحالة الحامل الصامت، مما يتيح استشارة وراثية دقيقة.
Q: How should I prepare for the blood collection?
س: كيف أستعد لعملية سحب الدم؟
Complete the Genomics Clinical Information Form and give blood; no dietary or medication changes required. You only need to fill the mandatory Genomics Clinical Information Requisition Form (Form 20) with accurate personal and medical history. A minimum of 2 mL whole blood in a lavender‑top EDTA tube is collected, ideally 4 mL. No fasting or stopping medications (including iron chelators) is necessary, unless your doctor specifies otherwise. The form is available at the time of home collection or can be sent electronically.
يكفي تعبئة نموذج المعلومات الجينومية السريرية (النموذج 20) وتقديم عينة دم؛ لا حاجة للصيام أو تغيير الأدوية.
Q: When will I receive my results, and what support is provided?
س: متى أستلم النتائج وما الدعم المتاح؟
Report is delivered on Friday if sample collected Monday by 9 AM; telephonic counseling available. After collection by 9 am Monday (cold‑chain maintained), the molecular analysis takes 5 working days; the final report is released on Friday. A dedicated clinical team provides a complimentary telephonic consultation to explain the findings in plain language. You may also schedule an in‑depth session with our genetic counselor. Results include clear diagnostic interpretation and recommended next steps.
يُصدر التقرير يوم الجمعة إذا تم سحب العينة الاثنين قبل التاسعة صباحًا، وتتوفر استشارة هاتفية مجانية لتوضيح النتائج.
Licensed Facility: 9834453. ISO 9001:2015 Certified (INT/EGQ/2509DA/3139). Adheres to Federal Decree‑Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), and UAE PDPL (Federal Decree-Law No. 45 of 2021). Sample logistics: home collection 8 AM‑11 PM. For assistance call or WhatsApp +971 54 548 8731.
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians