TEL/AML1 Qualitative Test
At DNA Labs UAE, we offer the TEL/AML1 Qualitative Test at a cost of AED 900.0. This test is used for the diagnosis of pediatric acute lymphoblastic leukemia (ALL) and involves the detection and characterization of the TEL/AML1 fusion gene in leukemia cells.
Test Details
The TEL/AML1 fusion gene is a result of the translocation t(12;21)(p13;q22), which is commonly found in pediatric ALL. This fusion gene involves the TEL (ETV6) gene on chromosome 12 and the AML1 (RUNX1) gene on chromosome 21. The qualitative analysis of TEL/AML1 can be done using molecular techniques such as polymerase chain reaction (PCR) or fluorescence in situ hybridization (FISH).
Importance of Qualitative Analysis
The qualitative analysis of TEL/AML1 is important for both prognostic and therapeutic purposes. The presence of the TEL/AML1 fusion gene is associated with a favorable prognosis in pediatric ALL, as it is often linked to low-risk disease and a higher likelihood of achieving remission. Therefore, the detection of this fusion gene can help guide treatment decisions and determine the appropriate intensity of therapy.
Test Procedure
The TEL/AML1 Qualitative Test requires a bone marrow or peripheral blood sample, which should be transported immediately to maintain sample condition. The test is performed using Real Time PCR method in our Genetics Test Department.
Report Delivery and Pre Test Information
After the sample is received, the report will be delivered within 3-4 days. It is important to note that a Doctor’s prescription is required for the TEL/AML1 Qualitative Test, except for surgery and pregnancy cases or individuals planning to travel abroad.
Conclusion
In conclusion, the TEL/AML1 Qualitative Test offered by DNA Labs UAE is a crucial diagnostic tool for TEL/AML1-positive ALL. It helps in confirming the presence of the TEL/AML1 fusion gene and determining the prognosis and appropriate treatment approach for affected patients. If you suspect pediatric acute lymphoblastic leukemia, consult a General Physician and consider the TEL/AML1 Qualitative Test for accurate diagnosis and personalized treatment.
Test Name | TELAML1 Qualitative Test |
---|---|
Components | EDTA Vacutainer (2ml) |
Price | 900.0 AED |
Sample Condition | Bone marrow \/ Peripheral blood (Transport immediately) |
Report Delivery | 3-4 days |
Method | Real Time PCR |
Test type | Genetics |
Doctor | General Physician |
Test Department: | |
Pre Test Information | TEL/AML1 Qualitative can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
Test Details |
TEL/AML1 is a fusion gene resulting from the translocation t(12;21)(p13;q22), which is commonly found in pediatric acute lymphoblastic leukemia (ALL). This translocation involves the fusion of the TEL (ETV6) gene on chromosome 12 with the AML1 (RUNX1) gene on chromosome 21. Qualitative analysis of TEL/AML1 involves the detection and characterization of this fusion gene in leukemia cells. This can be done using various molecular techniques such as polymerase chain reaction (PCR) or fluorescence in situ hybridization (FISH). These methods can identify the presence of the TEL/AML1 fusion gene and confirm the diagnosis of TEL/AML1-positive ALL. Qualitative analysis of TEL/AML1 is important for prognostic and therapeutic purposes. The presence of TEL/AML1 fusion gene is associated with a favorable prognosis in pediatric ALL, as it is often associated with low-risk disease and a higher likelihood of achieving remission. Therefore, its detection can help guide treatment decisions and determine the appropriate intensity of therapy. In summary, qualitative analysis of TEL/AML1 involves the detection and characterization of the TEL/AML1 fusion gene in leukemia cells. This analysis is important for diagnosing TEL/AML1-positive ALL and determining the prognosis and treatment approach for affected patients. |