Test Price
2,800 AED✅ Home Collection Available
TANC2 Gene NGS Test for Brain Disorders in UAE | 2,800 AED | DHA 2026 Guidelines
تحليل جين TANC2 للاضطرابات الدماغية في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي
UAE Compliance: This genetic test fully complies with Federal Decree-Law No. 41 of 2024, Art. 87 on genetic consent and confidentiality; قانون الطفل المعدل 2026 (CDS Law 2026) mandates guardian consent for minors; and UAE PDPL ensures end‑to‑end data privacy.
Clinical Executive Summary
ملخص تنفيذي: اختبار تسلسل الجينوم الكامل لجين TANC2 بتقنية NGS للكشف عن الطفرات المسببة لاضطرابات الدماغ، بدقة تشخيصية 99.9%، مع استشارة ما بعد الفحص.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing (ISO 9001:2015 Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview
The TANC2 Gene NGS Test analyzes the entire coding region and splice sites of the TANC2 gene using Next-Generation Sequencing to detect pathogenic variants associated with a spectrum of neurodevelopmental disorders, including brain malformations, intellectual disability, and dysmorphic features. This test is essential for accurate diagnosis, genetic counseling, and personalized management plans.
| Feature | Our TANC2 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | Full gene coverage with CNV detection and deep intronic variant analysis | Limited to predefined exons, miss large deletions/duplications |
| Methodology | Next-Generation Sequencing (NGS) with ACMG/AMP variant classification | Sanger sequencing – lower throughput, higher cost per variant |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks (often outsourced) |
2026 ICD-10-CM: Q87.8 (Other specified congenital malformation syndromes), G93.89 (Other specified disorders of brain), Z15.89 (Genetic susceptibility to other disease) | LOINC: 95900-9 (TANC2 full gene sequencing)
Physician Insight & Safety Protocol
"As a clinical geneticist, I know that a TANC2 variant result must be interpreted within the full clinical context—neuroimaging, developmental history, and family pedigree are crucial. This test does not replace a thorough clinical evaluation; it provides molecular evidence to guide diagnosis and management. Always correlate with phenotype before concluding pathogenicity." – Dr. PRABHAKAR REDDY (DHA: 61713011)
⚠ Medication Safety Warning: DO NOT discontinue any prescribed medication without consulting your treating physician. Genetic testing does not alter acute treatment plans.
Exclusion Criteria & Emergency Red Flags
- Inability to provide informed consent (or legal guardian consent for minors).
- Unstable clinical condition requiring immediate medical attention (e.g., acute seizures, respiratory distress).
- Recent blood transfusion (within 2 weeks) may cause chimerism in blood DNA – use buccal swab if necessary.
- ER Red Flag: If the patient experiences sudden neurological deterioration, severe headache, or loss of consciousness, seek emergency care immediately and inform the laboratory of any urgent testing results.
Patient FAQ & Clinical Guidance
1. What is the TANC2 gene and why is this test important?
The TANC2 gene provides instructions for a protein that helps organize synapses in the brain; pathogenic variants can cause a spectrum of neurodevelopmental disorders including intellectual disability, autism, seizures, and brain malformations. (This enables precise molecular diagnosis, guiding early intervention and genetic counseling.)
2. How is the sample collected and is a doctor's referral required?
A simple blood draw (or buccal swab) can be performed at home by our ISO-certified phlebotomy team, or at our facility. A valid medical referral and genetic counseling session are mandatory to ensure proper clinical indication and informed consent.
3. كم مدة انتظار النتائج وماذا تعني النتيجة السلبية؟
تستغرق النتائج 3 إلى 4 أسابيع، والنتيجة السلبية تعني عدم العثور على طفرة ممرضة في جين TANC2، ولكنها لا تستبعد اضطرابات جينية أخرى، وقد يوصي الطبيب بفحوصات إضافية.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians