Test Price
2,800 AED✅ Home Collection Available
LARS2 Gene Hydrops, Lactic Acidosis, and Sideroblastic Anemia (HLASA) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity via ISO Certified Processing
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM – 11 PM)
Telephonic Post-Test Clinical Interpretation Support by Consultant Medical Geneticist
Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
The LARS2 NGS test precisely identifies pathogenic variants in the LARS2 gene, confirming Hydrops, Lactic Acidosis, and Sideroblastic Anemia (HLASA) syndrome, a rare mitochondrial disorder. Full gene sequencing combined with CNV detection provides comprehensive diagnostic coverage for this complex condition.
| Features | Our HLASA NGS Test | Standard Sanger Panel |
|---|---|---|
| Genetic Coverage | Full LARS2 gene sequencing + CNV detection | Limited to selected exons, missing copy number changes |
| Methodology | Next Generation Sequencing (NGS) – high sensitivity | Sanger sequencing – lower throughput |
| Turnaround Time | 3–4 Weeks (comprehensive report) | 4–6 Weeks or longer for multiple exons |
Physician Insight & Safety Protocols
"This genetic test provides definitive molecular confirmation for HLASA syndrome, a rare mitochondrial disorder with significant clinical implications. Interpretation must be correlated with hematologic parameters, lactate levels, and imaging findings. I strongly recommend both pre-test and post-test genetic counselling to ensure patients and families understand the implications for management and reproductive planning."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Safety Advisory: Genetic Counselling Requirement
Federal Decree-Law No. 4 of 2016 on Medical Liability mandates that all genetic testing be accompanied by professional counselling. A licensed genetic counsellor must review the consent form and family pedigree before sample collection proceeds.
Exclusion Criteria & Emergency Red Flags
- Age under 18 years without parental/guardian consent and presence.
- Acute febrile illness or clinically unstable condition requiring hospital monitoring.
- Inability to provide a viable blood/DNA sample (severe thrombocytopenia/coagulopathy).
- Refusal of pre-test genetic counselling as mandated by Federal Decree-Law No. 4 of 2016.
- Severe anemia symptoms: chest pain, shortness of breath, dizziness, or syncope.
- Signs of hydrops: rapid weight gain, respiratory distress, pallor, or edema.
- Persistent lactic acidosis signs: deep, rapid breathing, confusion, extreme fatigue.
- Any sudden deterioration—call 998 immediately.
Patient FAQ & Clinical Guidance
1. What is the LARS2 gene test used for?
Identifying LARS2 gene mutations enables precise diagnosis of HLASA syndrome, guiding clinical management and family planning decisions.
2. How is the test performed?
Next Generation Sequencing (NGS) is performed on a peripheral blood sample, extracted DNA, or FTA card to detect LARS2 gene mutations with high sensitivity and specificity.
3. When will I receive the results?
Results are delivered within 3–4 weeks following sample receipt, accompanied by a dedicated telephonic post-test clinical guidance session.
4. Is genetic counselling required before testing?
Yes, pre-test genetic counselling is mandatory under UAE law. A licensed genetic counsellor will review the implications, benefits, and limitations of testing before obtaining informed consent.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Security: This service fully complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-controlled, and processed within secure UAE-based infrastructure. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Laboratory Accreditation: DNA Labs UAE operates under DHA Facility License Number 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. Processes are ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | LARS2 Gene Hydrops, Lactic Acidosis, and Sideroblastic Anemia (HLASA) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood, Extracted DNA, or FTA Card |
| Methodology Used | Next Generation Sequencing (NGS) + CNV Detection |
| ICD-10-CM Code | D64.0 |
| LOINC Code | 94266-3 |
| DHA Facility License & Laboratory Address | License #1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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