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RUNX1-RUNX1T1 AML1- ETO t8;21 Quantitative Test

Original price was: 1,600 د.إ.Current price is: 1,200 د.إ.

-25%

The RUNX1-RUNX1T1 AML1-ETO t(8;21) Quantitative Test is a specialized diagnostic assay designed to detect the presence of the RUNX1-RUNX1T1 fusion gene, which results from the translocation between chromosomes 8 and 21, specifically t(8;21)(q22;q22). This genetic abnormality is a hallmark of certain types of acute myeloid leukemia (AML), particularly those classified as M2 under the French-American-British (FAB) classification system. The presence of this fusion gene is associated with a distinct clinical course and has implications for treatment strategies and prognosis.

The test utilizes advanced molecular techniques to quantitatively measure the levels of the RUNX1-RUNX1T1 transcript in the patient’s blood or bone marrow samples. This allows for not only the diagnosis of AML with the t(8;21) translocation but also the monitoring of disease progression and response to therapy, making it an invaluable tool in the management of patients with this subtype of leukemia.

Performed at DNA Labs UAE, the RUNX1-RUNX1T1 AML1-ETO t(8;21) Quantitative Test is priced at 1200 AED. DNA Labs UAE is equipped with state-of-the-art facilities and staffed by highly skilled professionals, ensuring accurate and reliable test results. This test represents a critical step in the personalized care of patients with AML, guiding therapeutic decisions and contributing to improved outcomes.

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RUNX1-RUNX1T1 AML1-ETO t8;21 Quantitative Test

Test Name: RUNX1-RUNX1T1 AML1-ETO t8;21 Quantitative Test

Components: EDTA Vacutainer (2ml)

Price: 1200.0 AED

Sample Condition: Bone marrow / Peripheral blood (Transport immediately)

Report Delivery: 3-4 days

Method: Real Time PCR

Test Type: Genetics

Doctor: General Physician

Test Department: Pre Test Information

RUNX1-RUNX1T1 (AML1-ETO) t(8;21) Quantitative can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details

The t(8;21) translocation, also known as the RUNX1-RUNX1T1 translocation or AML1-ETO fusion gene, is a chromosomal abnormality commonly found in acute myeloid leukemia (AML). This translocation involves the fusion of two genes, RUNX1 and RUNX1T1, resulting in the production of a chimeric protein called AML1-ETO.

Quantitative analysis of the RUNX1-RUNX1T1 fusion gene is typically performed using molecular techniques such as polymerase chain reaction (PCR) or fluorescence in situ hybridization (FISH). These techniques allow for the detection and quantification of the fusion gene in patient samples.

The quantitative analysis of the RUNX1-RUNX1T1 fusion gene is important for several reasons. Firstly, it can be used for diagnosis and classification of AML, as the presence of this fusion gene is a characteristic feature of t(8;21) AML. Secondly, it can be used for monitoring disease progression and treatment response in patients with t(8;21) AML. Changes in the levels of the fusion gene over time can provide valuable information about the effectiveness of therapy.

Quantitative analysis of the RUNX1-RUNX1T1 fusion gene is typically reported as a ratio of the fusion gene to a reference gene, such as a housekeeping gene. This ratio can be used to determine the level of the fusion gene in the patient sample and compare it to normal levels.

Overall, quantitative analysis of the RUNX1-RUNX1T1 fusion gene is an important tool in the diagnosis, classification, and monitoring of t(8;21) AML.

Test Name RUNX1-RUNX1T1 AML1- ETO t8;21 Quantitative Test
Components EDTA Vacutainer (2ml)
Price 1200.0 AED
Sample Condition Bone marrow \/ Peripheral blood (Transport immediately)
Report Delivery 3-4 days
Method Real Time PCR
Test type Genetics
Doctor General Physician
Test Department:
Pre Test Information RUNX1-RUNX1T1 (AML1- ETO) t(8;21) Quantitative can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

The t(8;21) translocation, also known as the RUNX1-RUNX1T1 translocation or AML1-ETO fusion gene, is a chromosomal abnormality commonly found in acute myeloid leukemia (AML). This translocation involves the fusion of two genes, RUNX1 and RUNX1T1, resulting in the production of a chimeric protein called AML1-ETO.

Quantitative analysis of the RUNX1-RUNX1T1 fusion gene is typically performed using molecular techniques such as polymerase chain reaction (PCR) or fluorescence in situ hybridization (FISH). These techniques allow for the detection and quantification of the fusion gene in patient samples.

The quantitative analysis of the RUNX1-RUNX1T1 fusion gene is important for several reasons. Firstly, it can be used for diagnosis and classification of AML, as the presence of this fusion gene is a characteristic feature of t(8;21) AML. Secondly, it can be used for monitoring disease progression and treatment response in patients with t(8;21) AML. Changes in the levels of the fusion gene over time can provide valuable information about the effectiveness of therapy.

Quantitative analysis of the RUNX1-RUNX1T1 fusion gene is typically reported as a ratio of the fusion gene to a reference gene, such as a housekeeping gene. This ratio can be used to determine the level of the fusion gene in the patient sample and compare it to normal levels.

Overall, quantitative analysis of the RUNX1-RUNX1T1 fusion gene is an important tool in the diagnosis, classification, and monitoring of t(8;21) AML.