Test Price
3,000 AED✅ Home Collection Available
Eukaryotic mRNA Sequencing De Novo Data Analysis (RNA‑seq) in UAE | AED 3,000
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑certified wet‑lab and advanced bioinformatics.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary telephonic post‑test interpretation by a qualified clinical scientist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
- Facility Accreditation: DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE
Test Overview & Methodology
Comprehensive Transcriptome Discovery
De novo mRNA sequencing captures the entire transcriptome without relying on a reference genome, enabling discovery of novel transcripts, splice variants, and fusion genes across oncological, rheumatological, and rare disease applications. This test is ideal for research‑driven diagnostics and biomarker discovery where reference‑based methods miss private or structural alterations.
| Feature | Our Test (De Novo) | Reference‑Based RNA‑seq |
|---|---|---|
| Assembly method | De novo (Trinity/SPAdes), reference‑free | Alignment to hg38 reference genome |
| Novel transcript detection | Full – captures novel isoforms & fusion genes | Limited; misses unannotated events |
| Library & sequencer | Illumina NovaSeq 6000, paired‑end 2×150 bp | Same chemistry possible, but pipeline differs |
| Turnaround time | 4 weeks | 2–4 weeks |
| Clinical relevance | Ideal for unknown aetiology, rare disease, cancer subtyping | Standard for known gene expression profiling |
Physician Insight & Safety Protocols
"Every de novo transcriptome is a unique biological fingerprint, but it must be correlated with your complete clinical picture. I encourage you to review these results with your treating physician to translate molecular findings into a personalised care plan. Your wellbeing is the heart of every decision we make."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Safety Advisory: Do Not Discontinue Medication Without Medical Consultation
Always consult your prescribing physician before stopping or altering any medication. The results of this test are intended to guide clinical decisions, not replace them.
Exclusion Criteria & ER Red Flags
- Whole blood must be collected in a PAXgene Blood RNA Tube; samples in EDTA or serum tubes will be rejected.
- Not suitable if you have received a blood transfusion within the last 14 days.
- Active haemolysis or visible clot in the sample invalidates the test.
- If you develop sudden swelling, increasing pain, or signs of infection at the venipuncture site, seek immediate medical attention.
Patient FAQ & Clinical Guidance
1. What is mRNA sequencing de novo and how does it differ from standard RNA‑seq?
De novo mRNA sequencing assembles the complete transcriptome without a reference genome, capturing novel transcripts and fusion genes undetectable by alignment‑based methods. This makes it especially powerful for discovering previously uncharacterised biomarkers in rare diseases and cancer.
2. How should I prepare for the blood collection?
No fasting or medication changes are needed; simply inform our phlebotomist if you are taking anticoagulants to ensure a safe, comfortable draw. The collection uses a specialised PAXgene tube that stabilises RNA immediately.
3. When will I receive my results and how are they delivered?
Results are finalized within 4 weeks and shared via a secure online portal with optional telephonic clinical interpretation. A detailed bioinformatics report accompanies the raw data, enabling seamless discussion with your specialist.
UAE Regulatory & Data Privacy Adherence
Your Data, Our Commitment
This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability. All patient data is encrypted, access-restricted, and handled under strict confidentiality agreements. Clinical results are released only to authorised healthcare providers and the patient.
Clinical & Logistical Metadata
| Parameter | Value |
|---|---|
| Test Name | Eukaryotic mRNA Sequencing De Novo Data Analysis (RNA‑seq) |
| Price (AED) | 3,000 |
| Turnaround Time | 4 weeks |
| Sample Type / Matrix | Whole blood – PAXgene Blood RNA Tube |
| Methodology Used | De novo assembly (Trinity/SPAdes) on Illumina NovaSeq 6000, paired‑end 2×150 bp |
| ICD‑10‑CM Code | Z01.8 |
| LOINC Code | 93005-4 |
| DHA Facility License & Laboratory Address Invariants | 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians