Test Price
2,800 AED✅ Home Collection Available
ABCB11 Gene Progressive Intrahepatic Cholestasis Type 2 (PFIC2) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين ABCB11 لنقص الصفراء التقدمي العائلي من النوع الثاني (PFIC2) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next‑Generation Sequencing.
- Premium Logistics: ISO Certified Cold‑Chain Home Collection by VIP Mobile Phlebotomist (8 AM – 11 PM).
- Clinical Guidance: Complimentary Telephonic Post‑Test Clinical Result Interpretation by Specialist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
الملخص التنفيذي: دقة تشخيصية 99.9% بتقنية التسلسل الجيني المعتمدة ISO، وسحب منزلي مبرد مع مستشار وراثي، وإرشاد طبي هاتفي بعد النتيجة.
Test Overview
This next-generation sequencing test comprehensively analyzes the entire coding region of the ABCB11 gene to diagnose progressive familial intrahepatic cholestasis type 2 (PFIC2) with 99.9% diagnostic sensitivity; a mandatory pre‑test genetic counselling session and pedigree chart are provided. هذا التحليل بتقنية التسلسل الجيني المتطور يُشخّص نقص الصفراء التقدمي العائلي من النوع الثاني بدقة 99.9% ويستوجب جلسة استشارة وراثية وإعداد شجرة نسب قبل الاختبار.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative |
|---|---|---|
| Technology | Full Gene Next‑Generation Sequencing (NGS) | Targeted Mutation Panel / Biochemical Assays |
| Sensitivity | 99.9% | 70–85% (limited to known mutations) |
| Turnaround Time | 3–4 Weeks | Variable (often 6–8 weeks for send‑out) |
| Pre‑Test Genetic Counselling | Included (Mandatory Pedigree Charting) | Often not included |
Physician Insight & Safety Protocol
“As a specialist in metabolic and liver disorders, I understand the anxiety surrounding genetic testing. While this NGS panel provides powerful diagnostic insights, it must always be interpreted alongside clinical symptoms, liver function tests, and imaging. Please never make treatment decisions without comprehensive specialist consultation.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠️ Medication Warning: Do not discontinue prescribed medication (e.g., ursodeoxycholic acid, rifampicin) without consulting your treating physician.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Recent blood transfusion (<2 weeks), inability to provide informed consent for genetic testing, active acute illness that may interfere with phlebotomy.
- Emergency Red Flags – Seek Immediate Medical Attention: Rapid onset of severe jaundice with coagulopathy, hepatic encephalopathy (confusion, asterixis), or intractable pruritus unresponsive to standard therapy.
Patient FAQ & Clinical Guidance
Q1: What is the ABCB11 gene test and why is it done?
Answer: The ABCB11 gene test is a NGS-based genetic test that identifies mutations causing progressive familial intrahepatic cholestasis type 2 (PFIC2) for accurate diagnosis and family screening. هو تحليل جيني يكتشف الطفرات المسببة لنقص الصفراء التقدمي العائلي النوع الثاني لتشخيص دقيق وفحص أفراد العائلة. This is recommended for patients with unexplained cholestasis, elevated bile acids, or a family history of PFIC syndromes. A positive result helps guide targeted therapy with ileal bile acid transporter inhibitors, surgical biliary diversion, or early liver transplant evaluation.
Q2: How is the sample collected and how long do results take?
Answer: A small blood sample is drawn via home-based or clinic-based phlebotomy, and results are ready in 3 to 4 weeks using advanced sequencing technology. تُسحب عينة دم صغيرة عبر سحب منزلي أو بالعيادة، وتظهر النتيجة خلال 3 إلى 4 أسابيع بتقنية التسلسل المتقدمة. Our cold‑chain logistics ensure sample stability from collection to the ISO 9001:2015‑accredited laboratory. The mandatory genetic counselling session is conducted before the blood draw to document the family pedigree.
Q3: What does a positive result mean for my child or me?
Answer: A positive result confirms a diagnosis of PFIC2, guiding treatment options such as specialized bile acid therapy, possible liver transplant evaluation, or family planning. تؤكد النتيجة الإيجابية التشخيص مما يُوجه العلاج مثل أدوية الأحماض الصفراوية أو تقييم زراعة الكبد أو تنظيم الأسرة. It also allows cascade testing for at‑risk relatives. Because PFIC2 follows autosomal recessive inheritance, genetic counselling can estimate recurrence risk for future pregnancies. Always discuss results with your hepatologist or clinical geneticist.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians