IGLL1 Gene Agammaglobulinemia Type 2 Autosomal Recessive Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines

تحليل جين IGLL1 لمرض نقص غاما غلوبولين الدم من النوع الثاني المتنحي الجسدي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي

✅ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing

🚑 Premium Logistics: Hospital-Grade Home Collection with ISO-Certified Cold-Chain Transport — 8 AM to 11 PM

📞 Clinical Guidance: Complimentary post-test telephonic result interpretation with a genetic counsellor

📋 Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731

✅ ضمان الدقة: حساسية تشخيصية 99.9% عبر معالجة جينية معتمدة من ISO 9001:2015

🚑 خدمات لوجستية متميزة: سحب عينات منزلي بمعايير المستشفيات مع نقل مبرد معتمد من ISO

📞 إرشاد سريري: استشارة هاتفية مجانية بعد النتيجة مع مستشار جيني متخصص

📋 التأمين: التحقق المباشر من التغطية التأمينية عبر واتساب +971 54 548 8731

ISO 9001:2015

Cert: INT/EGQ/2509DA/3139

DHA License

9834453

Trusted UAE Lab

Clinical Test Overview & Competitive Comparison

The IGLL1 NGS test identifies pathogenic variants in the immunoglobulin lambda-like polypeptide 1 gene, confirming a diagnosis of autosomal recessive agammaglobulinemia type 2—a severe primary immunodeficiency characterized by absent B cells and profound hypogammaglobulinemia. Our next-generation sequencing assay covers all coding exons and splice junctions with >500x mean depth, delivering a definitive molecular diagnosis within 3–4 weeks.

Feature	Our IGLL1 NGS Test	Closest Alternative (Sanger/Panel)
Precision	99.9% analytical sensitivity for SNVs/indels	~98% limited to targeted regions
Methodology	NGS (Next Generation Sequencing) with full gene coverage	Sanger sequencing of selected exons
Turnaround Time	3–4 Weeks	4–6 Weeks
Sample Types	Whole Blood, Extracted DNA, FTA Card (one drop)	Whole Blood only

Physician Insight & Critical Safety Protocol

Dr. PRABHAKAR REDDY — DHA License 61713011

"As a haematologist, I emphasise that this test provides a genetic aetiology, but clinical correlation with immunoglobulin levels and B-cell phenotyping is mandatory. A negative IGLL1 result does not exclude all causes of agammaglobulinemia; variants in BTK and other genes must be considered. I urge every family to undergo comprehensive genetic counselling before sampling, as outlined in UAE Federal Law No. 41 of 2024."

⚠️ Medication Warning

Do not discontinue any prescribed immunoglobulin replacement therapy or antibiotics without direct consultation with your treating physician.

Exclusion Criteria & Emergency Red Flags

This test is not validated for diagnosis of acute infection or emergency setting.
Patients with current severe neutropenia or life-threatening sepsis should seek immediate emergency care, not rely on this genetic test.
Minors require explicit parental consent and a genetic counselling session per UAE CDS Law 2026.
If the patient has received allogeneic hematopoietic stem cell transplant within the last 6 months, donor DNA may confound results—please inform the lab before sampling.

Patient FAQ & Clinical Guidance

What exactly does the IGLL1 gene test detect?

This next-generation sequencing assay identifies pathogenic variants in the IGLL1 gene, which cause autosomal recessive agammaglobulinemia type 2—a condition marked by absent B cells and severe antibody deficiency since infancy.

يكشف هذا التحليل الجيني المتقدم عن الطفرات الممرضة في جين IGLL1 المسؤولة عن نقص غاما غلوبولين الدم الوراثي من النوع الثاني المتنحي، مما يساعد في التشخيص المبكر واتخاذ قرارات العلاج مدى الحياة.

How is the sample collected for this?

A certified phlebotomist arrives at your home between 8 AM and 11 PM to draw a small amount of whole blood; you can also provide a DNA sample on an FTA card if preferred.

يصل فني مختص إلى منزلك بين الساعة 8 صباحاً و11 مساءً لسحب عينة دم بسيطة، أو يمكنك تقديم عينة حمض نووي على بطاقة FTA وفقاً لمتطلبات الاختبار.

What happens after I receive my IGLL1 result?

A genetic counsellor will interpret your report in a complimentary telephonic session, explaining any identified variant and its implications for treatment and family planning.

بعد استلام النتيجة، سيقدم لك مستشار جيني شرحاً مجانياً عبر الهاتف لتفسير الطفرة المكتشفة وتأثيرها على خطة العلاج والاستشارة الوراثية للعائلة.

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