Test Price
2,800 AED✅ Home Collection Available
CCDC39 Gene — Primary Ciliary Dyskinesia Type 14 — Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين CCDC39 للكشف عن خلل الحركة الهدبي الأولي من النوع 14 بتقنية التسلسل الجيني المتقدم (NGS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: يقدم هذا الفحص تحليلاً جينياً شاملاً لجين CCDC39 للكشف عن الطفرات المسببة لمرض خلل الحركة الهدبي الأولي من النوع 14. بفضل تقنية التسلسل الجيني المتقدم، نضمن دقة تشخيصية تصل إلى 99.9% وفقاً لمعايير هيئة الصحة بدبي لعام 2026.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
1. Overview of CCDC39 Gene and Primary Ciliary Dyskinesia Type 14
The CCDC39 gene encodes a protein essential for ciliary movement. Mutations cause primary ciliary dyskinesia type 14 (PCD14), a rare autosomal recessive disorder affecting the respiratory tract, sinuses, and ears. This NGS-based test analyses the entire coding region of CCDC39, detecting single nucleotide variants, small insertions/deletions, and copy number changes to confirm clinical suspicion or carrier status. (تحليل شامل لجين CCDC39 لتشخيص خلل الحركة الهدبي الأولي بدقة فائقة.)
| Feature | Our Test – CCDC39 NGS Full Gene Analysis | Closest Alternative – Targeted Mutation Panel |
|---|---|---|
| Methodology | Next Generation Sequencing (NGS) with Illumina platform, confirmed by Sanger sequencing | Limited to pre-specified hot-spot mutations; may miss novel variants |
| Variant Detection | Full gene coverage including deep intronic regions and copy number variations | Partial gene coverage; no CNV detection |
| Turnaround Time | 3 to 4 Weeks | 2 to 3 Weeks |
| Diagnostic Yield | ~95% for primary ciliary dyskinesia type 14 | ~60% (dependent on ethnic background) |
2. Physician Insight & Safety Protocol
"As a clinical professional, I understand the anxiety that comes with genetic testing. A positive result can guide management of chronic ear, sinus, and lung complications, while a negative result offers peace of mind. Remember, this test should always be interpreted alongside your full clinical picture by your treating physician." — Dr. PRABHAKAR REDDY, DHA License: 61713011
✚ Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Genetic test results may affect management but should never prompt abrupt changes to your current therapy.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Active acute febrile illness; recent blood transfusion (within 2 weeks); inability to provide informed consent for genetic testing; skin infection at phlebotomy site.
- Emergency Red Flags (seek immediate medical care): Severe respiratory distress, cyanosis (bluish lips/skin), acute hearing loss, or high fever with chills. These require urgent evaluation unrelated to sample collection.
UAE Regulatory Compliance & Data Privacy
This service fully adheres to Federal Decree-Law No. 41 of 2024 on Medical Liability (Art. 87), UAE Child Data Safety Law 2026 for minor consent protocols, and UAE PDPL (Federal Decree-Law No. 45 of 2021) for genetic data privacy. Our laboratory operates under Facility License 9834453 and is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). All home collections are performed by DHA-licensed phlebotomists using cold-chain logistics.
3. Patient FAQ & Clinical Guidance
Q1: What is the purpose of CCDC39 gene testing and who should consider it?
SNIPPET: The CCDC39 gene test confirms primary ciliary dyskinesia type 14 by identifying disease-causing mutations in patients with chronic sino-pulmonary infections or infertility.
This test is ideal for children and adults with persistent wet cough, recurrent ear infections, nasal polyposis, or situs inversus. It also identifies carrier status in family members of affected individuals. Early diagnosis enables targeted respiratory physiotherapy and antibiotic prophylaxis to preserve lung function.
س1: ما الغرض من فحص جين CCDC39 ومن ينبغي أن يجريه؟
الملخص: يُؤكّد فحص جين CCDC39 تشخيص خلل الحركة الهدبي الأولي من النوع 14 عبر تحديد الطفرات المسببة للمرض لدى المرضى الذين يعانون من التهابات رئوية مزمنة أو عقم.
Q2: How should I prepare for the blood draw and is a genetic counselling session mandatory?
SNIPPET: No special fasting is required; however, a pre-test genetic counselling session is mandatory to discuss family history and draw a pedigree chart.
You will meet with a certified genetic counsellor (telephonic or in person) who explains the test’s scope, possible outcomes, and implications for your family. Blood collection (3-5 ml in EDTA tube) or dried blood spot on FTA card can be done at home between 8 AM and 11 PM. Do not stop any medications prior to collection.
س2: كيف أستعد لسحب الدم وهل جلسة الاستشارة الوراثية إلزامية؟
الملخص: لا تحتاج إلى صيام خاص، ولكن جلسة الاستشارة الوراثية قبل الفحص إلزامية لمناقشة التاريخ العائلي ورسم شجرة النسب.
Q3: What happens if my result is positive or uncertain, and how will I receive clinical guidance?
SNIPPET: A positive result confirms primary ciliary dyskinesia type 14 and triggers a post- telephonic consultation with a specialist to interpret next steps.
If a pathogenic variant is found, your ENT doctor or pulmonologist will integrate the finding with your clinical picture to tailor treatment—such as airway clearance techniques and hearing assessments. Variants of uncertain significance (VUS) are explained thoroughly, with optional family studies. Direct billing to insurance is verified via WhatsApp at +971 54 548 8731.
س3: ماذا لو كانت نتيجتي إيجابية أو غير مؤكدة، وكيف أحصل على التوجيه السريري؟
الملخص: النتيجة الإيجابية تؤكد الإصابة بخلل الحركة الهدبي الأولي من النوع 14 وتستدعي استشارة هاتفية بعد الفحص مع أخصائي لتفسير الخطوات التالية.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians